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Preclinical Molecular PET-CT Imaging Targeting CDCP1 in Colorectal Cancer.
Cuda TJ, He Y, Kryza T, Khan T, Tse BW, Sokolowski KA, Liu C, Lyons N, Gough M, Snell CE, Wyld DK, Rose S, Riddell AD, Stevenson ARL, Thomas PA, Clark DA, Puttick S, Hooper JD. Cuda TJ, et al. Among authors: khan t. Contrast Media Mol Imaging. 2021 Sep 13;2021:3153278. doi: 10.1155/2021/3153278. eCollection 2021. Contrast Media Mol Imaging. 2021. PMID: 34621145 Free PMC article.
Anti-CDCP1 immuno-conjugates for detection and inhibition of ovarian cancer.
Harrington BS, He Y, Khan T, Puttick S, Conroy PJ, Kryza T, Cuda T, Sokolowski KA, Tse BW, Robbins KK, Arachchige BJ, Stehbens SJ, Pollock PM, Reed S, Weroha SJ, Haluska P, Salomon C, Lourie R, Perrin LC, Law RHP, Whisstock JC, Hooper JD. Harrington BS, et al. Among authors: khan t. Theranostics. 2020 Jan 12;10(5):2095-2114. doi: 10.7150/thno.30736. eCollection 2020. Theranostics. 2020. PMID: 32104500 Free PMC article.
Effective targeting of intact and proteolysed CDCP1 for imaging and treatment of pancreatic ductal adenocarcinoma.
Kryza T, Khan T, Puttick S, Li C, Sokolowski KA, Tse BW, Cuda T, Lyons N, Gough M, Yin J, Parkin A, Deryugina EI, Quigley JP, Law RHP, Whisstock JC, Riddell AD, Barbour AP, Wyld DK, Thomas PA, Rose S, Snell CE, Pajic M, He Y, Hooper JD. Kryza T, et al. Among authors: khan t. Theranostics. 2020 Mar 4;10(9):4116-4133. doi: 10.7150/thno.43589. eCollection 2020. Theranostics. 2020. PMID: 32226543 Free PMC article.
Disruption of Glycogen Utilization Markedly Improves the Efficacy of Carboplatin against Preclinical Models of Clear Cell Ovarian Carcinoma.
Khan T, He Y, Kryza T, Harrington BS, Gunter JH, Sullivan MA, Cuda T, Rogers R, Davies CM, Broomfield A, Gough M, Wu AC, McGann T, Weroha SJ, Haluska P, Forbes JM, Armes JE, Barry SC, Coward JI, Jagasia N, Chetty N, Snell CE, Lourie R, Perrin LC, Hooper JD. Khan T, et al. Cancers (Basel). 2020 Apr 3;12(4):869. doi: 10.3390/cancers12040869. Cancers (Basel). 2020. PMID: 32260077 Free PMC article.
Substrate-biased activity-based probes identify proteases that cleave receptor CDCP1.
Kryza T, Khan T, Lovell S, Harrington BS, Yin J, Porazinski S, Pajic M, Koistinen H, Rantala JK, Dreyer T, Magdolen V, Reuning U, He Y, Tate EW, Hooper JD. Kryza T, et al. Among authors: khan t. Nat Chem Biol. 2021 Jul;17(7):776-783. doi: 10.1038/s41589-021-00783-w. Epub 2021 Apr 15. Nat Chem Biol. 2021. PMID: 33859413
Preclinical Evaluation of a Fluorescent Probe Targeting Receptor CDCP1 for Identification of Ovarian Cancer.
He Y, Khan T, Kryza T, Jones ML, Goh JB, Lyons NJ, Pearce LA, Lee MD, Gough M, Rogers R, Davies CM, Gilks CB, Hodgkinson T, Lourie R, Barry SC, Perrin LC, Williams CC, Puttick S, Adams TE, Munro TP, Hooper JD, Chetty N. He Y, et al. Among authors: khan t. Mol Pharm. 2021 Sep 6;18(9):3464-3474. doi: 10.1021/acs.molpharmaceut.1c00401. Epub 2021 Aug 27. Mol Pharm. 2021. PMID: 34448393
Elevating CDCA3 Levels Enhances Tyrosine Kinase Inhibitor Sensitivity in TKI-Resistant EGFR Mutant Non-Small-Cell Lung Cancer.
Sahin KB, Shah ET, Ferguson GP, Molloy C, Kalita-de Croft P, Hayes SA, Hudson A, Colvin E, Kamitakahara H, Harvie R, Hasovits C, Khan T, Duijf PHG, Howell VM, He Y, Bolderson E, Hooper JD, Lakhani SR, Richard DJ, O'Byrne KJ, Adams MN. Sahin KB, et al. Among authors: khan t. Cancers (Basel). 2021 Sep 16;13(18):4651. doi: 10.3390/cancers13184651. Cancers (Basel). 2021. PMID: 34572879 Free PMC article.
2,853 results