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Inherited human c-Rel deficiency disrupts myeloid and lymphoid immunity to multiple infectious agents.
Lévy R, Langlais D, Béziat V, Rapaport F, Rao G, Lazarov T, Bourgey M, Zhou YJ, Briand C, Moriya K, Ailal F, Avery DT, Markle J, Lim AI, Ogishi M, Yang R, Pelham S, Emam M, Migaud M, Deswarte C, Habib T, Saraiva LR, Moussa EA, Guennoun A, Boisson B, Belkaya S, Martinez-Barricarte R, Rosain J, Belkadi A, Breton S, Payne K, Benhsaien I, Plebani A, Lougaris V, Di Santo JP, Neven B, Abel L, Ma CS, Bousfiha AA, Marr N, Bustamante J, Liu K, Gros P, Geissmann F, Tangye SG, Casanova JL, Puel A. Lévy R, et al. Among authors: saraiva lr. J Clin Invest. 2021 Sep 1;131(17):e150143. doi: 10.1172/JCI150143. J Clin Invest. 2021. PMID: 34623332 Free PMC article.
Congenital iRHOM2 deficiency causes ADAM17 dysfunction and environmentally directed immunodysregulatory disease.
Kubo S, Fritz JM, Raquer-McKay HM, Kataria R, Vujkovic-Cvijin I, Al-Shaibi A, Yao Y, Zheng L, Zou J, Waldman AD, Jing X, Farley TK, Park AY, Oler AJ, Charles AK, Makhlouf M, AbouMoussa EH, Hasnah R, Saraiva LR, Ganesan S, Al-Subaiey AA, Matthews H, Flano E, Lee HH, Freeman AF, Sefer AP, Sayar E, Çakır E, Karakoc-Aydiner E, Baris S, Belkaid Y, Ozen A, Lo B, Lenardo MJ. Kubo S, et al. Among authors: saraiva lr. Nat Immunol. 2022 Jan;23(1):75-85. doi: 10.1038/s41590-021-01093-y. Epub 2021 Dec 22. Nat Immunol. 2022. PMID: 34937930 Free PMC article. Clinical Trial.
A transcriptomic atlas of mammalian olfactory mucosae reveals an evolutionary influence on food odor detection in humans.
Saraiva LR, Riveros-McKay F, Mezzavilla M, Abou-Moussa EH, Arayata CJ, Makhlouf M, Trimmer C, Ibarra-Soria X, Khan M, Van Gerven L, Jorissen M, Gibbs M, O'Flynn C, McGrane S, Mombaerts P, Marioni JC, Mainland JD, Logan DW. Saraiva LR, et al. Sci Adv. 2019 Jul 31;5(7):eaax0396. doi: 10.1126/sciadv.aax0396. eCollection 2019 Jul. Sci Adv. 2019. PMID: 31392275 Free PMC article.
Deconstructing the mouse olfactory percept through an ethological atlas.
Manoel D, Makhlouf M, Arayata CJ, Sathappan A, Da'as S, Abdelrahman D, Selvaraj S, Hasnah R, Mainland JD, Gerkin RC, Saraiva LR. Manoel D, et al. Among authors: saraiva lr. Curr Biol. 2021 Jul 12;31(13):2809-2818.e3. doi: 10.1016/j.cub.2021.04.020. Epub 2021 May 5. Curr Biol. 2021. PMID: 33957076 Free PMC article.
A 3D transcriptomics atlas of the mouse nose sheds light on the anatomical logic of smell.
Ruiz Tejada Segura ML, Abou Moussa E, Garabello E, Nakahara TS, Makhlouf M, Mathew LS, Wang L, Valle F, Huang SSY, Mainland JD, Caselle M, Osella M, Lorenz S, Reisert J, Logan DW, Malnic B, Scialdone A, Saraiva LR. Ruiz Tejada Segura ML, et al. Among authors: saraiva lr. Cell Rep. 2022 Mar 22;38(12):110547. doi: 10.1016/j.celrep.2022.110547. Cell Rep. 2022. PMID: 35320714 Free PMC article.
74 results