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1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity.
Legru A, Verdirosa F, Hernandez JF, Tassone G, Sannio F, Benvenuti M, Conde PA, Bossis G, Thomas CA, Crowder MW, Dillenberger M, Becker K, Pozzi C, Mangani S, Docquier JD, Gavara L. Legru A, et al. Among authors: becker k. Eur J Med Chem. 2021 Dec 15;226:113873. doi: 10.1016/j.ejmech.2021.113873. Epub 2021 Oct 4. Eur J Med Chem. 2021. PMID: 34626878
1,2,4-Triazole-3-thione Compounds as Inhibitors of Dizinc Metallo-β-lactamases.
Sevaille L, Gavara L, Bebrone C, De Luca F, Nauton L, Achard M, Mercuri P, Tanfoni S, Borgianni L, Guyon C, Lonjon P, Turan-Zitouni G, Dzieciolowski J, Becker K, Bénard L, Condon C, Maillard L, Martinez J, Frère JM, Dideberg O, Galleni M, Docquier JD, Hernandez JF. Sevaille L, et al. Among authors: becker k. ChemMedChem. 2017 Jun 21;12(12):972-985. doi: 10.1002/cmdc.201700186. Epub 2017 Jun 12. ChemMedChem. 2017. PMID: 28505394 Free article.
4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-β-lactamase inhibitors.
Gavara L, Sevaille L, De Luca F, Mercuri P, Bebrone C, Feller G, Legru A, Cerboni G, Tanfoni S, Baud D, Cutolo G, Bestgen B, Chelini G, Verdirosa F, Sannio F, Pozzi C, Benvenuti M, Kwapien K, Fischer M, Becker K, Frère JM, Mangani S, Gresh N, Berthomieu D, Galleni M, Docquier JD, Hernandez JF. Gavara L, et al. Among authors: becker k. Eur J Med Chem. 2020 Dec 15;208:112720. doi: 10.1016/j.ejmech.2020.112720. Epub 2020 Aug 20. Eur J Med Chem. 2020. PMID: 32937203 Free article.
Chemistry of polyhalogenated nitrobutadienes, 17: Efficient synthesis of persubstituted chloroquinolinyl-1H-pyrazoles and evaluation of their antimalarial, anti-SARS-CoV-2, antibacterial, and cytotoxic activities.
Zapol'skii VA, Berneburg I, Bilitewski U, Dillenberger M, Becker K, Jungwirth S, Shekhar A, Krueger B, Kaufmann DE. Zapol'skii VA, et al. Among authors: becker k. Beilstein J Org Chem. 2022 May 9;18:524-532. doi: 10.3762/bjoc.18.54. eCollection 2022. Beilstein J Org Chem. 2022. PMID: 35615535 Free PMC article.
3,838 results