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Page 1
Haplotype heterogeneity and low linkage disequilibrium reduce reliable prediction of genotypes for the ‑α 3.7I form of α-thalassaemia using genome-wide microarray data.
Ndila CM, Nyirongo V, Macharia AW, Jeffreys AE, Rowlands K, Hubbart C, Busby GBJ, Band G, Harding RM, Rockett KA, Williams TN; MalariaGEN Consortium. Ndila CM, et al. Among authors: hubbart c. Wellcome Open Res. 2021 Sep 22;5:287. doi: 10.12688/wellcomeopenres.16320.2. eCollection 2020. Wellcome Open Res. 2021. PMID: 34632085 Free PMC article.
Imputation-based meta-analysis of severe malaria in three African populations.
Band G, Le QS, Jostins L, Pirinen M, Kivinen K, Jallow M, Sisay-Joof F, Bojang K, Pinder M, Sirugo G, Conway DJ, Nyirongo V, Kachala D, Molyneux M, Taylor T, Ndila C, Peshu N, Marsh K, Williams TN, Alcock D, Andrews R, Edkins S, Gray E, Hubbart C, Jeffreys A, Rowlands K, Schuldt K, Clark TG, Small KS, Teo YY, Kwiatkowski DP, Rockett KA, Barrett JC, Spencer CC; Malaria Genomic Epidemiology Network. Band G, et al. Among authors: hubbart c. PLoS Genet. 2013 May;9(5):e1003509. doi: 10.1371/journal.pgen.1003509. Epub 2013 May 23. PLoS Genet. 2013. PMID: 23717212 Free PMC article.
Resistance to malaria through structural variation of red blood cell invasion receptors.
Leffler EM, Band G, Busby GBJ, Kivinen K, Le QS, Clarke GM, Bojang KA, Conway DJ, Jallow M, Sisay-Joof F, Bougouma EC, Mangano VD, Modiano D, Sirima SB, Achidi E, Apinjoh TO, Marsh K, Ndila CM, Peshu N, Williams TN, Drakeley C, Manjurano A, Reyburn H, Riley E, Kachala D, Molyneux M, Nyirongo V, Taylor T, Thornton N, Tilley L, Grimsley S, Drury E, Stalker J, Cornelius V, Hubbart C, Jeffreys AE, Rowlands K, Rockett KA, Spencer CCA, Kwiatkowski DP; Malaria Genomic Epidemiology Network. Leffler EM, et al. Among authors: hubbart c. Science. 2017 Jun 16;356(6343):eaam6393. doi: 10.1126/science.aam6393. Epub 2017 May 18. Science. 2017. PMID: 28522690 Free PMC article.
High-throughput genotyping assays for identification of glycophorin B deletion variants in population studies.
Amuzu DS, Rockett KA, Leffler EM, Ansah F, Amoako N, Morang'a CM, Hubbart C, Rowlands K, Jeffreys AE, Amenga-Etego LN, Kwiatkowski DP, Awandare GA. Amuzu DS, et al. Among authors: hubbart c. Exp Biol Med (Maywood). 2021 Apr;246(8):916-928. doi: 10.1177/1535370220968545. Epub 2020 Dec 16. Exp Biol Med (Maywood). 2021. PMID: 33325748 Free PMC article. Clinical Trial.
An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples.
MalariaGEN; Ahouidi A, Ali M, Almagro-Garcia J, Amambua-Ngwa A, Amaratunga C, Amato R, Amenga-Etego L, Andagalu B, Anderson TJC, Andrianaranjaka V, Apinjoh T, Ariani C, Ashley EA, Auburn S, Awandare GA, Ba H, Baraka V, Barry AE, Bejon P, Bertin GI, Boni MF, Borrmann S, Bousema T, Branch O, Bull PC, Busby GBJ, Chookajorn T, Chotivanich K, Claessens A, Conway D, Craig A, D'Alessandro U, Dama S, Day NP, Denis B, Diakite M, Djimdé A, Dolecek C, Dondorp AM, Drakeley C, Drury E, Duffy P, Echeverry DF, Egwang TG, Erko B, Fairhurst RM, Faiz A, Fanello CA, Fukuda MM, Gamboa D, Ghansah A, Golassa L, Goncalves S, Hamilton WL, Harrison GLA, Hart L, Henrichs C, Hien TT, Hill CA, Hodgson A, Hubbart C, Imwong M, Ishengoma DS, Jackson SA, Jacob CG, Jeffery B, Jeffreys AE, Johnson KJ, Jyothi D, Kamaliddin C, Kamau E, Kekre M, Kluczynski K, Kochakarn T, Konaté A, Kwiatkowski DP, Kyaw MP, Lim P, Lon C, Loua KM, Maïga-Ascofaré O, Malangone C, Manske M, Marfurt J, Marsh K, Mayxay M, Miles A, Miotto O, Mobegi V, Mokuolu OA, Montgomery J, Mueller I, Newton PN, Nguyen T, Nguyen TN, Noedl H, Nosten F, Noviyanti R, Nzila A, Ochola-Oyier LI, Ocholla H, Oduro A, Omedo I, Onyamboko MA, Ouedraogo JB, Oy… See abstract for full author list ➔ MalariaGEN, et al. Among authors: hubbart c. Wellcome Open Res. 2021 Jul 13;6:42. doi: 10.12688/wellcomeopenres.16168.2. eCollection 2021. Wellcome Open Res. 2021. PMID: 33824913 Free PMC article.
Malaria protection due to sickle haemoglobin depends on parasite genotype.
Band G, Leffler EM, Jallow M, Sisay-Joof F, Ndila CM, Macharia AW, Hubbart C, Jeffreys AE, Rowlands K, Nguyen T, Gonçalves S, Ariani CV, Stalker J, Pearson RD, Amato R, Drury E, Sirugo G, d'Alessandro U, Bojang KA, Marsh K, Peshu N, Saelens JW, Diakité M, Taylor SM, Conway DJ, Williams TN, Rockett KA, Kwiatkowski DP. Band G, et al. Among authors: hubbart c. Nature. 2022 Feb;602(7895):106-111. doi: 10.1038/s41586-021-04288-3. Epub 2021 Dec 9. Nature. 2022. PMID: 34883497 Free PMC article.
Geographic-genetic analysis of Plasmodium falciparum parasite populations from surveys of primary school children in Western Kenya.
Omedo I, Mogeni P, Rockett K, Kamau A, Hubbart C, Jeffreys A, Ochola-Oyier LI, de Villiers EP, Gitonga CW, Noor AM, Snow RW, Kwiatkowski D, Bejon P. Omedo I, et al. Among authors: hubbart c. Wellcome Open Res. 2017 Sep 5;2:29. doi: 10.12688/wellcomeopenres.11228.2. eCollection 2017. Wellcome Open Res. 2017. PMID: 28944299 Free PMC article.
Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study.
Ndila CM, Uyoga S, Macharia AW, Nyutu G, Peshu N, Ojal J, Shebe M, Awuondo KO, Mturi N, Tsofa B, Sepúlveda N, Clark TG, Band G, Clarke G, Rowlands K, Hubbart C, Jeffreys A, Kariuki S, Marsh K, Mackinnon M, Maitland K, Kwiatkowski DP, Rockett KA, Williams TN; MalariaGEN Consortium. Ndila CM, et al. Among authors: hubbart c. Lancet Haematol. 2018 Aug;5(8):e333-e345. doi: 10.1016/S2352-3026(18)30107-8. Epub 2018 Jul 20. Lancet Haematol. 2018. PMID: 30033078 Free PMC article.
Genetic determinants of anti-malarial acquired immunity in a large multi-centre study.
Shelton JM, Corran P, Risley P, Silva N, Hubbart C, Jeffreys A, Rowlands K, Craik R, Cornelius V, Hensmann M, Molloy S, Sepulveda N, Clark TG, Band G, Clarke GM, Spencer CC, Kerasidou A, Campino S, Auburn S, Tall A, Ly AB, Mercereau-Puijalon O, Sakuntabhai A, Djimdé A, Maiga B, Touré O, Doumbo OK, Dolo A, Troye-Blomberg M, Mangano VD, Verra F, Modiano D, Bougouma E, Sirima SB, Ibrahim M, Hussain A, Eid N, Elzein A, Mohammed H, Elhassan A, Elhassan I, Williams TN, Ndila C, Macharia A, Marsh K, Manjurano A, Reyburn H, Lemnge M, Ishengoma D, Carter R, Karunaweera N, Fernando D, Dewasurendra R, Drakeley CJ, Riley EM, Kwiatkowski DP, Rockett KA; MalariaGEN Consortium. Shelton JM, et al. Among authors: hubbart c. Malar J. 2015 Aug 28;14:333. doi: 10.1186/s12936-015-0833-x. Malar J. 2015. PMID: 26314886 Free PMC article.
45 results