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Page 1
Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells.
Fletcher RS, Ratajczak J, Doig CL, Oakey LA, Callingham R, Da Silva Xavier G, Garten A, Elhassan YS, Redpath P, Migaud ME, Philp A, Brenner C, Canto C, Lavery GG. Fletcher RS, et al. Among authors: canto c. Mol Metab. 2017 May 29;6(8):819-832. doi: 10.1016/j.molmet.2017.05.011. eCollection 2017 Aug. Mol Metab. 2017. PMID: 28752046 Free PMC article.
Endogenous nicotinamide riboside metabolism protects against diet-induced liver damage.
Sambeat A, Ratajczak J, Joffraud M, Sanchez-Garcia JL, Giner MP, Valsesia A, Giroud-Gerbetant J, Valera-Alberni M, Cercillieux A, Boutant M, Kulkarni SS, Moco S, Canto C. Sambeat A, et al. Among authors: canto c. Nat Commun. 2019 Sep 20;10(1):4291. doi: 10.1038/s41467-019-12262-x. Nat Commun. 2019. PMID: 31541116 Free PMC article.
A reduced form of nicotinamide riboside defines a new path for NAD+ biosynthesis and acts as an orally bioavailable NAD+ precursor.
Giroud-Gerbetant J, Joffraud M, Giner MP, Cercillieux A, Bartova S, Makarov MV, Zapata-Pérez R, Sánchez-García JL, Houtkooper RH, Migaud ME, Moco S, Canto C. Giroud-Gerbetant J, et al. Among authors: canto c. Mol Metab. 2019 Dec;30:192-202. doi: 10.1016/j.molmet.2019.09.013. Epub 2019 Oct 3. Mol Metab. 2019. PMID: 31767171 Free PMC article.
Nicotinamide riboside kinases regulate skeletal muscle fiber-type specification and are rate-limiting for metabolic adaptations during regeneration.
Sonntag T, Ancel S, Karaz S, Cichosz P, Jacot G, Giner MP, Sanchez-Garcia JL, Pannérec A, Moco S, Sorrentino V, Cantó C, Feige JN. Sonntag T, et al. Among authors: canto c. Front Cell Dev Biol. 2022 Nov 9;10:1049653. doi: 10.3389/fcell.2022.1049653. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 36438552 Free PMC article.
Trigonelline is an NAD+ precursor that improves muscle function during ageing and is reduced in human sarcopenia.
Membrez M, Migliavacca E, Christen S, Yaku K, Trieu J, Lee AK, Morandini F, Giner MP, Stiner J, Makarov MV, Garratt ES, Vasiloglou MF, Chanvillard L, Dalbram E, Ehrlich AM, Sanchez-Garcia JL, Canto C, Karagounis LG, Treebak JT, Migaud ME, Heshmat R, Razi F, Karnani N, Ostovar A, Farzadfar F, Tay SKH, Sanders MJ, Lillycrop KA, Godfrey KM, Nakagawa T, Moco S, Koopman R, Lynch GS, Sorrentino V, Feige JN. Membrez M, et al. Among authors: canto c. Nat Metab. 2024 Mar;6(3):433-447. doi: 10.1038/s42255-024-00997-x. Epub 2024 Mar 19. Nat Metab. 2024. PMID: 38504132 Free PMC article.
154 results