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Expansion of the 4-(Diethylamino)benzaldehyde Scaffold to Explore the Impact on Aldehyde Dehydrogenase Activity and Antiproliferative Activity in Prostate Cancer.
Ibrahim AIM, Batlle E, Sneha S, Jiménez R, Pequerul R, Parés X, Rüngeler T, Jha V, Tuccinardi T, Sadiq M, Frame F, Maitland NJ, Farrés J, Pors K. Ibrahim AIM, et al. Among authors: batlle e. J Med Chem. 2022 Mar 10;65(5):3833-3848. doi: 10.1021/acs.jmedchem.1c01367. Epub 2022 Feb 25. J Med Chem. 2022. PMID: 35212533 Free PMC article.
New Potent Inhibitor of Transforming Growth Factor-Beta (TGFβ) Signaling that is Efficacious against Microsatellite Stable Colorectal Cancer Metastasis in Combination with Immune Checkpoint Therapy in Mice.
Tauriello DVF, Sancho E, Byrom D, Sanchez-Zarzalejo C, Salvany M, Henriques A, Palomo-Ponce S, Sevillano M, Hernando-Momblona X, Matarin JA, Ramos I, Ruano I, Prats N, Batlle E, Riera A. Tauriello DVF, et al. Among authors: batlle e. ACS Pharmacol Transl Sci. 2024 Oct 1;8(1):97-112. doi: 10.1021/acsptsci.4c00374. eCollection 2025 Jan 10. ACS Pharmacol Transl Sci. 2024. PMID: 39816803
Long-range organization of intestinal 2D-crypts using exogenous Wnt3a micropatterning.
Larrañaga E, Marin-Riera M, Abad-Lázaro A, Bartolomé-Català D, Otero A, Fernández-Majada V, Batlle E, Sharpe J, Ojosnegros S, Comelles J, Martinez E. Larrañaga E, et al. Among authors: batlle e. Nat Commun. 2025 Jan 3;16(1):382. doi: 10.1038/s41467-024-55651-7. Nat Commun. 2025. PMID: 39753580 Free PMC article.
Five latent factors underlie response to immunotherapy.
Usset J, Rosendahl Huber A, Andrianova MA, Batlle E, Carles J, Cuppen E, Elez E, Felip E, Gómez-Rey M, Lo Giacco D, Martinez-Jimenez F, Muñoz-Couselo E, Siu LL, Tabernero J, Vivancos A, Muiños F, Gonzalez-Perez A, Lopez-Bigas N. Usset J, et al. Among authors: batlle e. Nat Genet. 2024 Oct;56(10):2112-2120. doi: 10.1038/s41588-024-01899-0. Epub 2024 Sep 12. Nat Genet. 2024. PMID: 39266764 Free PMC article.
Cancer drug-tolerant persister cells: from biological questions to clinical opportunities.
Russo M, Chen M, Mariella E, Peng H, Rehman SK, Sancho E, Sogari A, Toh TS, Balaban NQ, Batlle E, Bernards R, Garnett MJ, Hangauer M, Leucci E, Marine JC, O'Brien CA, Oren Y, Patton EE, Robert C, Rosenberg SM, Shen S, Bardelli A. Russo M, et al. Among authors: batlle e. Nat Rev Cancer. 2024 Oct;24(10):694-717. doi: 10.1038/s41568-024-00737-z. Epub 2024 Sep 2. Nat Rev Cancer. 2024. PMID: 39223250 Review.
Mutant TP53 switches therapeutic vulnerability during gastric cancer progression within interleukin-6 family cytokines.
Huber A, Allam AH, Dijkstra C, Thiem S, Huynh J, Poh AR, Konecnik J, Jacob SP, Busuttil R, Liao Y, Chisanga D, Shi W, Alorro MG, Forrow S, Tauriello DVF, Batlle E, Boussioutas A, Williams DS, Buchert M, Ernst M, Eissmann MF. Huber A, et al. Among authors: batlle e. Cell Rep. 2024 Aug 27;43(8):114616. doi: 10.1016/j.celrep.2024.114616. Epub 2024 Aug 9. Cell Rep. 2024. PMID: 39128004 Free PMC article.
Mechanisms of metastatic colorectal cancer.
Cañellas-Socias A, Sancho E, Batlle E. Cañellas-Socias A, et al. Among authors: batlle e. Nat Rev Gastroenterol Hepatol. 2024 Sep;21(9):609-625. doi: 10.1038/s41575-024-00934-z. Epub 2024 May 28. Nat Rev Gastroenterol Hepatol. 2024. PMID: 38806657 Review.
Membrane to cortex attachment determines different mechanical phenotypes in LGR5+ and LGR5- colorectal cancer cells.
Conti S, Venturini V, Cañellas-Socias A, Cortina C, Abenza JF, Stephan-Otto Attolini C, Middendorp Guerra E, Xu CK, Li JH, Rossetti L, Stassi G, Roca-Cusachs P, Diz-Muñoz A, Ruprecht V, Guck J, Batlle E, Labernadie A, Trepat X. Conti S, et al. Among authors: batlle e. Nat Commun. 2024 Apr 18;15(1):3363. doi: 10.1038/s41467-024-47227-2. Nat Commun. 2024. PMID: 38637494 Free PMC article.
151 results