Sisodia SS - Search Results

1

Nanoscale organization of Nicastrin, the substrate receptor of the γ-secretase complex, as independent molecular domains.

Kedia S, Mandal K, Netrakanti PR, Jose M, Sisodia SS, Nair D. Kedia S, et al. Among authors: sisodia ss. Mol Brain. 2021 Oct 13;14(1):158. doi: 10.1186/s13041-021-00855-x. Mol Brain. 2021. PMID: 34645511 Free PMC article.

2

Characterization of a presenilin-mediated amyloid precursor protein carboxyl-terminal fragment gamma. Evidence for distinct mechanisms involved in gamma -secretase processing of the APP and Notch1 transmembrane domains.

Yu C, Kim SH, Ikeuchi T, Xu H, Gasparini L, Wang R, Sisodia SS. Yu C, et al. Among authors: sisodia ss. J Biol Chem. 2001 Nov 23;276(47):43756-60. doi: 10.1074/jbc.C100410200. Epub 2001 Oct 2. J Biol Chem. 2001. PMID: 11583985 Free article.

3

Gamma-secretase: never more enigmatic.

Sisodia SS, Annaert W, Kim SH, De Strooper B. Sisodia SS, et al. Trends Neurosci. 2001 Nov;24(11 Suppl):S2-6. doi: 10.1016/s0166-2236(00)01987-1. Trends Neurosci. 2001. PMID: 11881741 Review.

4

Spatial segregation of gamma-secretase and substrates in distinct membrane domains.

Vetrivel KS, Cheng H, Kim SH, Chen Y, Barnes NY, Parent AT, Sisodia SS, Thinakaran G. Vetrivel KS, et al. Among authors: sisodia ss. J Biol Chem. 2005 Jul 8;280(27):25892-900. doi: 10.1074/jbc.M503570200. Epub 2005 May 10. J Biol Chem. 2005. PMID: 15886206 Free PMC article.

5

Identification of a tetratricopeptide repeat-like domain in the nicastrin subunit of γ-secretase using synthetic antibodies.

Zhang X, Hoey RJ, Lin G, Koide A, Leung B, Ahn K, Dolios G, Paduch M, Ikeuchi T, Wang R, Li YM, Koide S, Sisodia SS. Zhang X, et al. Among authors: sisodia ss. Proc Natl Acad Sci U S A. 2012 May 29;109(22):8534-9. doi: 10.1073/pnas.1202691109. Epub 2012 May 14. Proc Natl Acad Sci U S A. 2012. PMID: 22586122 Free PMC article.

6

Negative evidence for a role of APH1B T27I variant in Alzheimer's disease.

Zhang X, Zhang C, Prokopenko D, Liang Y, Han W, Tanzi RE, Sisodia SS. Zhang X, et al. Among authors: sisodia ss. Hum Mol Genet. 2020 Apr 15;29(6):955-966. doi: 10.1093/hmg/ddaa017. Hum Mol Genet. 2020. PMID: 31995180

7

Alteration in synaptic nanoscale organization dictates amyloidogenic processing in Alzheimer's disease.

Kedia S, Ramakrishna P, Netrakanti PR, Singh N, Sisodia SS, Jose M, Kumar S, Mahadevan A, Ramanan N, Nadkarni S, Nair D. Kedia S, et al. Among authors: sisodia ss. iScience. 2020 Dec 11;24(1):101924. doi: 10.1016/j.isci.2020.101924. eCollection 2021 Jan 22. iScience. 2020. PMID: 33409475 Free PMC article.

8

Requirement for presenilin 1 in facilitating lagged 2-mediated endoproteolysis and signaling of notch 1.

Martys-Zage JL, Kim SH, Berechid B, Bingham SJ, Chu S, Sklar J, Nye J, Sisodia SS. Martys-Zage JL, et al. Among authors: sisodia ss. J Mol Neurosci. 2000 Dec;15(3):189-204. doi: 10.1385/jmn:15:3:189. J Mol Neurosci. 2000. PMID: 11303783

9

gamma-Secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in?

Sisodia SS, St George-Hyslop PH. Sisodia SS, et al. Nat Rev Neurosci. 2002 Apr;3(4):281-90. doi: 10.1038/nrn785. Nat Rev Neurosci. 2002. PMID: 11967558 Review. No abstract available.

10

Cell-free generation of the notch1 intracellular domain (NICD) and APP-CTfgamma: evidence for distinct intramembranous "gamma-secretase" activities.

Ikeuchi T, Sisodia SS. Ikeuchi T, et al. Among authors: sisodia ss. Neuromolecular Med. 2002;1(1):43-54. doi: 10.1385/NMM:1:1:43. Neuromolecular Med. 2002. PMID: 12025815

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