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Neuropathic pain in the IMI-APPROACH knee osteoarthritis cohort: prevalence and phenotyping.
van Helvoort EM, Welsing PMJ, Jansen MP, Gielis WP, Loef M, Kloppenburg M, Blanco F, Haugen IK, Berenbaum F, Bay-Jensen AC, Ladel C, Lalande A, Larkin J, Loughlin J, Mobasheri A, Weinans H, Lafeber F, Eijkelkamp N, Mastbergen S. van Helvoort EM, et al. Among authors: lalande a. RMD Open. 2021 Dec;7(3):e002025. doi: 10.1136/rmdopen-2021-002025. RMD Open. 2021. PMID: 34911812 Free PMC article.
Structural tissue damage and 24-month progression of semi-quantitative MRI biomarkers of knee osteoarthritis in the IMI-APPROACH cohort.
Roemer FW, Jansen M, Marijnissen ACA, Guermazi A, Heiss R, Maschek S, Lalande A, Blanco FJ, Berenbaum F, van de Stadt LA, Kloppenburg M, Haugen IK, Ladel CH, Bacardit J, Wisser A, Eckstein F, Lafeber FPJG, Weinans HH, Wirth W. Roemer FW, et al. Among authors: lalande a. BMC Musculoskelet Disord. 2022 Nov 17;23(1):988. doi: 10.1186/s12891-022-05926-1. BMC Musculoskelet Disord. 2022. PMID: 36397054 Free PMC article. Clinical Trial.
Applications of transcriptomics in support of drug development for osteoarthritis.
Kaplon H, Luo Y, De Ceuninck F, Lalande A, Courtade-Gaiani S, Laigle L, Moingeon P. Kaplon H, et al. Among authors: lalande a. Osteoarthr Cartil Open. 2021 Nov 18;3(4):100221. doi: 10.1016/j.ocarto.2021.100221. eCollection 2021 Dec. Osteoarthr Cartil Open. 2021. PMID: 36474760 Free PMC article.
Serum ARGS-aggrecan in a phase 2 clinical trial targeting osteoarthritis.
Larsson S, Lalande A, Stefan Lohmander L, Soret P, Bernard K, Pueyo M, Struglics A. Larsson S, et al. Among authors: lalande a. Osteoarthritis Cartilage. 2024 Nov;32(11):1463-1470. doi: 10.1016/j.joca.2024.06.003. Epub 2024 Jun 9. Osteoarthritis Cartilage. 2024. PMID: 38862084 Free article. Clinical Trial.
Cohort profile: The Applied Public-Private Research enabling OsteoArthritis Clinical Headway (IMI-APPROACH) study: a 2-year, European, cohort study to describe, validate and predict phenotypes of osteoarthritis using clinical, imaging and biochemical markers.
van Helvoort EM, van Spil WE, Jansen MP, Welsing PMJ, Kloppenburg M, Loef M, Blanco FJ, Haugen IK, Berenbaum F, Bacardit J, Ladel CH, Loughlin J, Bay-Jensen AC, Mobasheri A, Larkin J, Boere J, Weinans HH, Lalande A, Marijnissen ACA, Lafeber FPJG. van Helvoort EM, et al. Among authors: lalande a. BMJ Open. 2020 Jul 28;10(7):e035101. doi: 10.1136/bmjopen-2019-035101. BMJ Open. 2020. PMID: 32723735 Free PMC article.
Predicted and actual 2-year structural and pain progression in the IMI-APPROACH knee osteoarthritis cohort.
van Helvoort EM, Jansen MP, Marijnissen ACA, Kloppenburg M, Blanco FJ, Haugen IK, Berenbaum F, Bay-Jensen AC, Ladel C, Lalande A, Larkin J, Loughlin J, Mobasheri A, Weinans HH, Widera P, Bacardit J, Welsing PMJ, Lafeber FPJG. van Helvoort EM, et al. Among authors: lalande a. Rheumatology (Oxford). 2022 Dec 23;62(1):147-157. doi: 10.1093/rheumatology/keac292. Rheumatology (Oxford). 2022. PMID: 35575381 Free PMC article.
Development and validation of a machine learning-supported strategy of patient selection for osteoarthritis clinical trials: the IMI-APPROACH study.
Widera P, Welsing PMJ, Danso SO, Peelen S, Kloppenburg M, Loef M, Marijnissen AC, van Helvoort EM, Blanco FJ, Magalhães J, Berenbaum F, Haugen IK, Bay-Jensen AC, Mobasheri A, Ladel C, Loughlin J, Lafeber FPJG, Lalande A, Larkin J, Weinans H, Bacardit J. Widera P, et al. Among authors: lalande a. Osteoarthr Cartil Open. 2023 Aug 18;5(4):100406. doi: 10.1016/j.ocarto.2023.100406. eCollection 2023 Dec. Osteoarthr Cartil Open. 2023. PMID: 37649530 Free PMC article.
Safety, Pharmacokinetics, and Pharmacodynamics of the ADAMTS-5 Inhibitor GLPG1972/S201086 in Healthy Volunteers and Participants With Osteoarthritis of the Knee or Hip.
van der Aar E, Deckx H, Dupont S, Fieuw A, Delage S, Larsson S, Struglics A, Lohmander LS, Lalande A, Leroux E, Amantini D, Passier P. van der Aar E, et al. Among authors: lalande a. Clin Pharmacol Drug Dev. 2022 Jan;11(1):112-122. doi: 10.1002/cpdd.1042. Epub 2021 Dec 2. Clin Pharmacol Drug Dev. 2022. PMID: 34859612 Free PMC article.
142 results