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Disrupting D1-NMDA or D2-NMDA receptor heteromerization prevents cocaine's rewarding effects but preserves natural reward processing.
Andrianarivelo A, Saint-Jour E, Pousinha P, Fernandez SP, Petitbon A, De Smedt-Peyrusse V, Heck N, Ortiz V, Allichon MC, Kappès V, Betuing S, Walle R, Zhu Y, Joséphine C, Bemelmans AP, Turecki G, Mechawar N, Javitch JA, Caboche J, Trifilieff P, Barik J, Vanhoutte P. Andrianarivelo A, et al. Among authors: allichon mc. Sci Adv. 2021 Oct 22;7(43):eabg5970. doi: 10.1126/sciadv.abg5970. Epub 2021 Oct 20. Sci Adv. 2021. PMID: 34669474 Free PMC article.
Npas4 regulates medium spiny neuron physiology and gates cocaine-induced hyperlocomotion.
Lissek T, Andrianarivelo A, Saint-Jour E, Allichon MC, Bauersachs HG, Nassar M, Piette C, Pruunsild P, Tan YW, Forget B, Heck N, Caboche J, Venance L, Vanhoutte P, Bading H. Lissek T, et al. Among authors: allichon mc. EMBO Rep. 2021 Dec 6;22(12):e51882. doi: 10.15252/embr.202051882. Epub 2021 Oct 18. EMBO Rep. 2021. PMID: 34661342 Free PMC article.
Cell-type- and region-specific modulation of cocaine seeking by micro-RNA-1 in striatal projection neurons.
Forget B, Garcia EM, Godino A, Rodriguez LD, Kappes V, Poirier P, Andrianarivelo A, Marchan ES, Allichon MC, Marias M, Vanhoutte P, Girault JA, Maldonado R, Caboche J. Forget B, et al. Among authors: allichon mc. Mol Psychiatry. 2022 Feb;27(2):918-928. doi: 10.1038/s41380-021-01328-2. Epub 2021 Nov 16. Mol Psychiatry. 2022. PMID: 34785784 Free PMC article.