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Crystal structure of SARS-CoV-2 main protease in complex with protease inhibitor PF-07321332.
Zhao Y, Fang C, Zhang Q, Zhang R, Zhao X, Duan Y, Wang H, Zhu Y, Feng L, Zhao J, Shao M, Yang X, Zhang L, Peng C, Yang K, Ma D, Rao Z, Yang H. Zhao Y, et al. Among authors: peng c. Protein Cell. 2022 Sep;13(9):689-693. doi: 10.1007/s13238-021-00883-2. Epub 2021 Oct 22. Protein Cell. 2022. PMID: 34687004 Free PMC article. No abstract available.
Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors.
Jin Z, Du X, Xu Y, Deng Y, Liu M, Zhao Y, Zhang B, Li X, Zhang L, Peng C, Duan Y, Yu J, Wang L, Yang K, Liu F, Jiang R, Yang X, You T, Liu X, Yang X, Bai F, Liu H, Liu X, Guddat LW, Xu W, Xiao G, Qin C, Shi Z, Jiang H, Rao Z, Yang H. Jin Z, et al. Among authors: peng c. Nature. 2020 Jun;582(7811):289-293. doi: 10.1038/s41586-020-2223-y. Epub 2020 Apr 9. Nature. 2020. PMID: 32272481
High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors.
Zhao Y, Du X, Duan Y, Pan X, Sun Y, You T, Han L, Jin Z, Shang W, Yu J, Guo H, Liu Q, Wu Y, Peng C, Wang J, Zhu C, Yang X, Yang K, Lei Y, Guddat LW, Xu W, Xiao G, Sun L, Zhang L, Rao Z, Yang H. Zhao Y, et al. Among authors: peng c. Protein Cell. 2021 Nov;12(11):877-888. doi: 10.1007/s13238-021-00836-9. Epub 2021 Apr 17. Protein Cell. 2021. PMID: 33864621 Free PMC article.
Identification of proteasome and caspase inhibitors targeting SARS-CoV-2 Mpro.
Wang Z, Zhao Y, Wang Q, Xing Y, Feng L, Kong J, Peng C, Zhang L, Yang H, Lu M. Wang Z, et al. Among authors: peng c. Signal Transduct Target Ther. 2021 Jun 1;6(1):214. doi: 10.1038/s41392-021-00639-8. Signal Transduct Target Ther. 2021. PMID: 34075025 Free PMC article. No abstract available.
Crystal structure and activation mechanism of DR3 death domain.
Yin X, Li W, Ma H, Zeng W, Peng C, Li Y, Liu M, Chen Q, Zhou R, Jin T. Yin X, et al. Among authors: peng c. FEBS J. 2019 Jul;286(13):2593-2610. doi: 10.1111/febs.14834. Epub 2019 Apr 11. FEBS J. 2019. PMID: 30941855 Free article.
Cryo-EM structure of human SAGA transcriptional coactivator complex.
Zhang Y, Yin C, Yin Y, Wei M, Jing W, Peng C, Chen Z, Huang J. Zhang Y, et al. Among authors: peng c. Cell Discov. 2022 Nov 22;8(1):125. doi: 10.1038/s41421-022-00489-w. Cell Discov. 2022. PMID: 36414614 Free PMC article. No abstract available.
ORP8 acts as a lipophagy receptor to mediate lipid droplet turnover.
Pu M, Zheng W, Zhang H, Wan W, Peng C, Chen X, Liu X, Xu Z, Zhou T, Sun Q, Neculai D, Liu W. Pu M, et al. Among authors: peng c. Protein Cell. 2023 Sep 14;14(9):653-667. doi: 10.1093/procel/pwac063. Protein Cell. 2023. PMID: 37707322 Free PMC article.
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