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Tryptophan and its metabolites in normal physiology and cancer etiology.
Perez-Castro L, Garcia R, Venkateswaran N, Barnes S, Conacci-Sorrell M. Perez-Castro L, et al. Among authors: venkateswaran n. FEBS J. 2023 Jan;290(1):7-27. doi: 10.1111/febs.16245. Epub 2021 Nov 7. FEBS J. 2023. PMID: 34687129 Free PMC article. Review.
MYC leads the way.
Venkateswaran N, Conacci-Sorrell M. Venkateswaran N, et al. Small GTPases. 2020 Mar;11(2):86-94. doi: 10.1080/21541248.2017.1364821. Epub 2017 Nov 25. Small GTPases. 2020. PMID: 29173017 Free PMC article. Review.
MYC promotes tryptophan uptake and metabolism by the kynurenine pathway in colon cancer.
Venkateswaran N, Lafita-Navarro MC, Hao YH, Kilgore JA, Perez-Castro L, Braverman J, Borenstein-Auerbach N, Kim M, Lesner NP, Mishra P, Brabletz T, Shay JW, DeBerardinis RJ, Williams NS, Yilmaz OH, Conacci-Sorrell M. Venkateswaran N, et al. Genes Dev. 2019 Sep 1;33(17-18):1236-1251. doi: 10.1101/gad.327056.119. Epub 2019 Aug 15. Genes Dev. 2019. PMID: 31416966 Free PMC article.
Kynurenine: an oncometabolite in colon cancer.
Venkateswaran N, Conacci-Sorrell M. Venkateswaran N, et al. Cell Stress. 2020 Jan 3;4(1):24-26. doi: 10.15698/cst2020.01.210. Cell Stress. 2020. PMID: 31922097 Free PMC article.
Inhibition of the de novo pyrimidine biosynthesis pathway limits ribosomal RNA transcription causing nucleolar stress in glioblastoma cells.
Lafita-Navarro MC, Venkateswaran N, Kilgore JA, Kanji S, Han J, Barnes S, Williams NS, Buszczak M, Burma S, Conacci-Sorrell M. Lafita-Navarro MC, et al. Among authors: venkateswaran n. PLoS Genet. 2020 Nov 17;16(11):e1009117. doi: 10.1371/journal.pgen.1009117. eCollection 2020 Nov. PLoS Genet. 2020. PMID: 33201894 Free PMC article.
The AHR target gene scinderin activates the WNT pathway by facilitating the nuclear translocation of β-catenin.
Perez-Castro L, Venkateswaran N, Garcia R, Hao YH, Lafita-Navarro MC, Kim J, Segal D, Saponzik E, Chang BJ, Fiolka R, Danuser G, Xu L, Brabletz T, Conacci-Sorrell M. Perez-Castro L, et al. Among authors: venkateswaran n. J Cell Sci. 2022 Oct 15;135(20):jcs260028. doi: 10.1242/jcs.260028. Epub 2022 Oct 27. J Cell Sci. 2022. PMID: 36148682 Free PMC article.
Activating an Adaptive Immune Response with a Telomerase-Mediated Telomere Targeting Therapeutic in Hepatocellular Carcinoma.
Mender I, Siteni S, Barron S, Flusche AM, Kubota N, Yu C, Cornelius C, Tedone E, Maziveyi M, Grichuk A, Venkateswaran N, Conacci-Sorrell M, Hoshida Y, Kang R, Tang D, Gryaznov S, Shay JW. Mender I, et al. Among authors: venkateswaran n. Mol Cancer Ther. 2023 Jun 1;22(6):737-750. doi: 10.1158/1535-7163.MCT-23-0039. Mol Cancer Ther. 2023. PMID: 37070671 Free PMC article.
ZNF692 organizes a hub specialized in 40S ribosomal subunit maturation enhancing translation in rapidly proliferating cells.
Lafita-Navarro MC, Hao YH, Jiang C, Jang S, Chang TC, Brown IN, Venkateswaran N, Maurais E, Stachera W, Zhang Y, Mundy D, Han J, Tran VM, Mettlen M, Xu L, Woodruff JB, Grishin NV, Kinch L, Mendell JT, Buszczak M, Conacci-Sorrell M. Lafita-Navarro MC, et al. Among authors: venkateswaran n. Cell Rep. 2023 Oct 31;42(10):113280. doi: 10.1016/j.celrep.2023.113280. Epub 2023 Oct 16. Cell Rep. 2023. PMID: 37851577 Free PMC article.
Anchorage-independent cell proliferation promoted by fascin's F-actin bundling.
Isogai T, Murali VS, Zhou F, Wang X, Rajendran D, Perez-Castro L, Venkateswaran N, Conacci-Sorrell M, Danuser G. Isogai T, et al. Among authors: venkateswaran n. bioRxiv [Preprint]. 2024 May 4:2024.05.04.592404. doi: 10.1101/2024.05.04.592404. bioRxiv. 2024. PMID: 38746129 Free PMC article. Preprint.
114 results