Wilson DW - Search Results

1

Host-directed therapy, an untapped opportunity for antimalarial intervention.

Wei L, Adderley J, Leroy D, Drewry DH, Wilson DW, Kaushansky A, Doerig C. Wei L, et al. Among authors: wilson dw. Cell Rep Med. 2021 Oct 19;2(10):100423. doi: 10.1016/j.xcrm.2021.100423. Cell Rep Med. 2021. PMID: 34693368 Free PMC article. Review.

2

Structure-Based Identification and Functional Characterization of a Lipocalin in the Malaria Parasite Plasmodium falciparum.

Burda PC, Crosskey T, Lauk K, Zurborg A, Söhnchen C, Liffner B, Wilcke L, Pietsch E, Strauss J, Jeffries CM, Svergun DI, Wilson DW, Wilmanns M, Gilberger TW. Burda PC, et al. Among authors: wilson dw. Cell Rep. 2020 Jun 23;31(12):107817. doi: 10.1016/j.celrep.2020.107817. Cell Rep. 2020. PMID: 32579913 Free article.

3

Analysis of erythrocyte signalling pathways during Plasmodium falciparum infection identifies targets for host-directed antimalarial intervention.

Adderley JD, John von Freyend S, Jackson SA, Bird MJ, Burns AL, Anar B, Metcalf T, Semblat JP, Billker O, Wilson DW, Doerig C. Adderley JD, et al. Among authors: wilson dw. Nat Commun. 2020 Aug 11;11(1):4015. doi: 10.1038/s41467-020-17829-7. Nat Commun. 2020. PMID: 32782246 Free PMC article.

4

Retargeting azithromycin analogues to have dual-modality antimalarial activity.

Burns AL, Sleebs BE, Siddiqui G, De Paoli AE, Anderson D, Liffner B, Harvey R, Beeson JG, Creek DJ, Goodman CD, McFadden GI, Wilson DW. Burns AL, et al. Among authors: wilson dw. BMC Biol. 2020 Sep 29;18(1):133. doi: 10.1186/s12915-020-00859-4. BMC Biol. 2020. PMID: 32993629 Free PMC article.

5

Targeting malaria parasite invasion of red blood cells as an antimalarial strategy.

Burns AL, Dans MG, Balbin JM, de Koning-Ward TF, Gilson PR, Beeson JG, Boyle MJ, Wilson DW. Burns AL, et al. Among authors: wilson dw. FEMS Microbiol Rev. 2019 May 1;43(3):223-238. doi: 10.1093/femsre/fuz005. FEMS Microbiol Rev. 2019. PMID: 30753425 Free PMC article. Review.

6

Screening the Medicines for Malaria Venture Pathogen Box for invasion and egress inhibitors of the blood stage of Plasmodium falciparum reveals several inhibitory compounds.

Dans MG, Weiss GE, Wilson DW, Sleebs BE, Crabb BS, de Koning-Ward TF, Gilson PR. Dans MG, et al. Among authors: wilson dw. Int J Parasitol. 2020 Mar;50(3):235-252. doi: 10.1016/j.ijpara.2020.01.002. Epub 2020 Mar 3. Int J Parasitol. 2020. PMID: 32135179 Free article.

7

Structure activity refinement of phenylsulfonyl piperazines as antimalarials that block erythrocytic invasion.

Nguyen W, Dans MG, Ngo A, Gancheva MR, Romeo O, Duffy S, de Koning-Ward TF, Lowes KN, Sabroux HJ, Avery VM, Wilson DW, Gilson PR, Sleebs BE. Nguyen W, et al. Among authors: wilson dw. Eur J Med Chem. 2021 Mar 15;214:113253. doi: 10.1016/j.ejmech.2021.113253. Epub 2021 Feb 4. Eur J Med Chem. 2021. PMID: 33610028

8

Property activity refinement of 2-anilino 4-amino substituted quinazolines as antimalarials with fast acting asexual parasite activity.

Ashton TD, Ngo A, Favuzza P, Bullen HE, Gancheva MR, Romeo O, Parkyn Schneider M, Nguyen N, Steel RWJ, Duffy S, Lowes KN, Sabroux HJ, Avery VM, Boddey JA, Wilson DW, Cowman AF, Gilson PR, Sleebs BE. Ashton TD, et al. Among authors: wilson dw. Bioorg Chem. 2021 Dec;117:105359. doi: 10.1016/j.bioorg.2021.105359. Epub 2021 Sep 21. Bioorg Chem. 2021. PMID: 34689083

9

Targeting malaria parasites with novel derivatives of azithromycin.

Burns AL, Sleebs BE, Gancheva M, McLean KT, Siddiqui G, Venter H, Beeson JG, O'Handley R, Creek DJ, Ma S, Frölich S, Goodman CD, McFadden GI, Wilson DW. Burns AL, et al. Among authors: wilson dw. Front Cell Infect Microbiol. 2022 Nov 30;12:1063407. doi: 10.3389/fcimb.2022.1063407. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 36530422 Free PMC article.

10

Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum.

Wilson DW, Goodman CD, Sleebs BE, Weiss GE, de Jong NW, Angrisano F, Langer C, Baum J, Crabb BS, Gilson PR, McFadden GI, Beeson JG. Wilson DW, et al. BMC Biol. 2015 Jul 18;13:52. doi: 10.1186/s12915-015-0162-0. BMC Biol. 2015. PMID: 26187647 Free PMC article.

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