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Azaindole Based Potentiator of Antibiotics against Gram-Negative Bacteria.
Sharma S, Rao R, Reeve SM, Phelps GA, Bharatham N, Katagihallimath N, Ramachandran V, Raveendran S, Sarma M, Nath A, Thomas T, Manickam D, Nagaraj S, Balasubramanian V, Lee RE, Hameed P S, Datta S. Sharma S, et al. Among authors: balasubramanian v. ACS Infect Dis. 2021 Nov 12;7(11):3009-3024. doi: 10.1021/acsinfecdis.1c00171. Epub 2021 Oct 26. ACS Infect Dis. 2021. PMID: 34699190
Nitrothiophene carboxamides, a novel narrow spectrum antibacterial series: Mechanism of action and Efficacy.
Hameed P S, Bharatham N, Katagihallimath N, Sharma S, Nandishaiah R, Shanbhag AP, Thomas T, Narjari R, Sarma M, Bhowmik P, Amar P, Ravishankar R, Jayaraman R, Muthan K, Subbiah R, Ramachandran V, Balasubramanian V, Datta S. Hameed P S, et al. Among authors: balasubramanian v. Sci Rep. 2018 May 8;8(1):7263. doi: 10.1038/s41598-018-25407-7. Sci Rep. 2018. PMID: 29740005 Free PMC article.
Combating Multidrug-Resistant Bacteria by Integrating a Novel Target Site Penetration and Receptor Binding Assay Platform Into Translational Modeling.
Lang Y, Shah NR, Tao X, Reeve SM, Zhou J, Moya B, Sayed ARM, Dharuman S, Oyer JL, Copik AJ, Fleischer BA, Shin E, Werkman C, Basso KB, Deveson Lucas D, Sutaria DS, Mégroz M, Kim TH, Loudon-Hossler V, Wright A, Jimenez-Nieves RH, Wallace MJ, Cadet KC, Jiao Y, Boyce JD, LoVullo ED, Schweizer HP, Bonomo RA, Bharatham N, Tsuji BT, Landersdorfer CB, Norris MH, Soo Shin B, Louie A, Balasubramanian V, Lee RE, Drusano GL, Bulitta JB. Lang Y, et al. Among authors: balasubramanian v. Clin Pharmacol Ther. 2021 Apr;109(4):1000-1020. doi: 10.1002/cpt.2205. Epub 2021 Mar 24. Clin Pharmacol Ther. 2021. PMID: 33576025 Free PMC article.
Simple and rapid method to determine antimycobacterial potency of compounds by using autoluminescent Mycobacterium tuberculosis.
Sharma S, Gelman E, Narayan C, Bhattacharjee D, Achar V, Humnabadkar V, Balasubramanian V, Ramachandran V, Dhar N, Dinesh N. Sharma S, et al. Among authors: balasubramanian v. Antimicrob Agents Chemother. 2014 Oct;58(10):5801-8. doi: 10.1128/AAC.03205-14. Epub 2014 Jul 21. Antimicrob Agents Chemother. 2014. PMID: 25049243 Free PMC article.
In vitro and in vivo efficacy of β-lactams against replicating and slowly growing/nonreplicating Mycobacterium tuberculosis.
Solapure S, Dinesh N, Shandil R, Ramachandran V, Sharma S, Bhattacharjee D, Ganguly S, Reddy J, Ahuja V, Panduga V, Parab M, Vishwas KG, Kumar N, Balganesh M, Balasubramanian V. Solapure S, et al. Among authors: balasubramanian v. Antimicrob Agents Chemother. 2013 Jun;57(6):2506-10. doi: 10.1128/AAC.00023-13. Epub 2013 Mar 18. Antimicrob Agents Chemother. 2013. PMID: 23507276 Free PMC article.
In silico-based high-throughput screen for discovery of novel combinations for tuberculosis treatment.
Singh R, Ramachandran V, Shandil R, Sharma S, Khandelwal S, Karmarkar M, Kumar N, Solapure S, Saralaya R, Nanduri R, Panduga V, Reddy J, Prabhakar KR, Rajagopalan S, Rao N, Narayanan S, Anandkumar A, Balasubramanian V, Datta S. Singh R, et al. Among authors: balasubramanian v. Antimicrob Agents Chemother. 2015 Sep;59(9):5664-74. doi: 10.1128/AAC.05148-14. Epub 2015 Jul 6. Antimicrob Agents Chemother. 2015. PMID: 26149995 Free PMC article.
Nitroarenes as Antitubercular Agents: Stereoelectronic Modulation to Mitigate Mutagenicity.
Landge S, Ramachandran V, Kumar A, Neres J, Murugan K, Sadler C, Fellows MD, Humnabadkar V, Vachaspati P, Raichurkar A, Sharma S, Ravishankar S, Guptha S, Sambandamurthy VK, Balganesh TS, Ugarkar BG, Balasubramanian V, Bandodkar BS, Panda M. Landge S, et al. Among authors: balasubramanian v. ChemMedChem. 2016 Feb 4;11(3):331-9. doi: 10.1002/cmdc.201500462. Epub 2016 Jan 11. ChemMedChem. 2016. PMID: 26751718
Discovery of Imidazo[1,2-a]pyridine Ethers and Squaramides as Selective and Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthesis.
Tantry SJ, Markad SD, Shinde V, Bhat J, Balakrishnan G, Gupta AK, Ambady A, Raichurkar A, Kedari C, Sharma S, Mudugal NV, Narayan A, Naveen Kumar CN, Nanduri R, Bharath S, Reddy J, Panduga V, Prabhakar KR, Kandaswamy K, Saralaya R, Kaur P, Dinesh N, Guptha S, Rich K, Murray D, Plant H, Preston M, Ashton H, Plant D, Walsh J, Alcock P, Naylor K, Collier M, Whiteaker J, McLaughlin RE, Mallya M, Panda M, Rudrapatna S, Ramachandran V, Shandil R, Sambandamurthy VK, Mdluli K, Cooper CB, Rubin H, Yano T, Iyer P, Narayanan S, Kavanagh S, Mukherjee K, Balasubramanian V, Hosagrahara VP, Solapure S, Ravishankar S, Hameed P S. Tantry SJ, et al. Among authors: balasubramanian v. J Med Chem. 2017 Feb 23;60(4):1379-1399. doi: 10.1021/acs.jmedchem.6b01358. Epub 2017 Feb 3. J Med Chem. 2017. PMID: 28075132
Bactericidal activity and mechanism of action of AZD5847, a novel oxazolidinone for treatment of tuberculosis.
Balasubramanian V, Solapure S, Iyer H, Ghosh A, Sharma S, Kaur P, Deepthi R, Subbulakshmi V, Ramya V, Ramachandran V, Balganesh M, Wright L, Melnick D, Butler SL, Sambandamurthy VK. Balasubramanian V, et al. Antimicrob Agents Chemother. 2014;58(1):495-502. doi: 10.1128/AAC.01903-13. Epub 2013 Nov 4. Antimicrob Agents Chemother. 2014. PMID: 24189255 Free PMC article.
460 results