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Albumin-targeting of an oxaliplatin-releasing platinum(iv) prodrug results in pronounced anticancer activity due to endocytotic drug uptake in vivo.
Schueffl H, Theiner S, Hermann G, Mayr J, Fronik P, Groza D, van Schonhooven S, Galvez L, Sommerfeld NS, Schintlmeister A, Reipert S, Wagner M, Mader RM, Koellensperger G, Keppler BK, Berger W, Kowol CR, Legin A, Heffeter P. Schueffl H, et al. Among authors: koellensperger g. Chem Sci. 2021 Aug 26;12(38):12587-12599. doi: 10.1039/d1sc03311e. eCollection 2021 Oct 6. Chem Sci. 2021. PMID: 34703544 Free PMC article.
Intracellular protein binding patterns of the anticancer ruthenium drugs KP1019 and KP1339.
Heffeter P, Böck K, Atil B, Reza Hoda MA, Körner W, Bartel C, Jungwirth U, Keppler BK, Micksche M, Berger W, Koellensperger G. Heffeter P, et al. Among authors: koellensperger g. J Biol Inorg Chem. 2010 Jun;15(5):737-48. doi: 10.1007/s00775-010-0642-1. Epub 2010 Mar 11. J Biol Inorg Chem. 2010. PMID: 20221888 Free PMC article.
Triapine-mediated ABCB1 induction via PKC induces widespread therapy unresponsiveness but is not underlying acquired triapine resistance.
Miklos W, Pelivan K, Kowol CR, Pirker C, Dornetshuber-Fleiss R, Spitzwieser M, Englinger B, van Schoonhoven S, Cichna-Markl M, Koellensperger G, Keppler BK, Berger W, Heffeter P. Miklos W, et al. Among authors: koellensperger g. Cancer Lett. 2015 May 28;361(1):112-20. doi: 10.1016/j.canlet.2015.02.049. Epub 2015 Mar 5. Cancer Lett. 2015. PMID: 25749419
151 results