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Identification of ER-000444793, a Cyclophilin D-independent inhibitor of mitochondrial permeability transition, using a high-throughput screen in cryopreserved mitochondria.
Briston T, Lewis S, Koglin M, Mistry K, Shen Y, Hartopp N, Katsumata R, Fukumoto H, Duchen MR, Szabadkai G, Staddon JM, Roberts M, Powney B. Briston T, et al. Among authors: staddon jm. Sci Rep. 2016 Nov 25;6:37798. doi: 10.1038/srep37798. Sci Rep. 2016. PMID: 27886240 Free PMC article.
Signal transduction at the blood-brain barrier.
Staddon JM, Herrenknecht K, Schulze C, Smales C, Rubin LL. Staddon JM, et al. Biochem Soc Trans. 1995 Aug;23(3):475-9. doi: 10.1042/bst0230475. Biochem Soc Trans. 1995. PMID: 8566371 Review. No abstract available.
Pre-clinical characterisation of E2814, a high-affinity antibody targeting the microtubule-binding repeat domain of tau for passive immunotherapy in Alzheimer's disease.
Roberts M, Sevastou I, Imaizumi Y, Mistry K, Talma S, Dey M, Gartlon J, Ochiai H, Zhou Z, Akasofu S, Tokuhara N, Ogo M, Aoyama M, Aoyagi H, Strand K, Sajedi E, Agarwala KL, Spidel J, Albone E, Horie K, Staddon JM, de Silva R. Roberts M, et al. Among authors: staddon jm. Acta Neuropathol Commun. 2020 Feb 4;8(1):13. doi: 10.1186/s40478-020-0884-2. Acta Neuropathol Commun. 2020. PMID: 32019610 Free PMC article.
Functional assessment of glucocerebrosidase modulator efficacy in primary patient-derived macrophages is essential for drug development and patient stratification.
Welsh NJ, Gewinner CA, Mistry K, Koglin M, Cooke J, Butler M, Powney B, Roberts M, Staddon JM, Schapira AHV. Welsh NJ, et al. Among authors: staddon jm. Haematologica. 2020 May;105(5):e206-e209. doi: 10.3324/haematol.2019.224717. Epub 2019 Sep 26. Haematologica. 2020. PMID: 31558665 Free PMC article. No abstract available.
51 results