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Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity.
Schönberger K, Obier N, Romero-Mulero MC, Cauchy P, Mess J, Pavlovich PV, Zhang YW, Mitterer M, Rettkowski J, Lalioti ME, Jäcklein K, Curtis JD, Féret B, Sommerkamp P, Morganti C, Ito K, Ghyselinck NB, Trompouki E, Buescher JM, Pearce EL, Cabezas-Wallscheid N. Schönberger K, et al. Among authors: morganti c. Cell Stem Cell. 2022 Jan 6;29(1):131-148.e10. doi: 10.1016/j.stem.2021.10.002. Epub 2021 Oct 26. Cell Stem Cell. 2022. PMID: 34706256 Free PMC article.
Metabolic Regulation of Hematopoietic Stem Cells.
Morganti C, Cabezas-Wallscheid N, Ito K. Morganti C, et al. Hemasphere. 2022 Jun 28;6(7):e740. doi: 10.1097/HS9.0000000000000740. eCollection 2022 Jul. Hemasphere. 2022. PMID: 35785147 Free PMC article. Review.
A mitochondrial NADPH-cholesterol axis regulates extracellular vesicle biogenesis to support hematopoietic stem cell fate.
Bonora M, Morganti C, van Gastel N, Ito K, Calura E, Zanolla I, Ferroni L, Zhang Y, Jung Y, Sales G, Martini P, Nakamura T, Lasorsa FM, Finkel T, Lin CP, Zavan B, Pinton P, Georgakoudi I, Romualdi C, Scadden DT, Ito K. Bonora M, et al. Among authors: morganti c. Cell Stem Cell. 2024 Mar 7;31(3):359-377.e10. doi: 10.1016/j.stem.2024.02.004. Cell Stem Cell. 2024. PMID: 38458178 Free article.
Metabolism and HSC fate: what NADPH is made for.
Morganti C, Bonora M, Ito K. Morganti C, et al. Trends Cell Biol. 2024 Jul 24:S0962-8924(24)00141-7. doi: 10.1016/j.tcb.2024.07.003. Online ahead of print. Trends Cell Biol. 2024. PMID: 39054107 Review.
Actinomycin D Targets NPM1c-Primed Mitochondria to Restore PML-Driven Senescence in AML Therapy.
Wu HC, Rérolle D, Berthier C, Hleihel R, Sakamoto T, Quentin S, Benhenda S, Morganti C, Wu C, Conte L, Rimsky S, Sebert M, Clappier E, Souquere S, Gachet S, Soulier J, Durand S, Trowbridge JJ, Bénit P, Rustin P, El Hajj H, Raffoux E, Ades L, Itzykson R, Dombret H, Fenaux P, Espeli O, Kroemer G, Brunetti L, Mak TW, Lallemand-Breitenbach V, Bazarbachi A, Falini B, Ito K, Martelli MP, de Thé H. Wu HC, et al. Among authors: morganti c. Cancer Discov. 2021 Dec 1;11(12):3198-3213. doi: 10.1158/2159-8290.CD-21-0177. Cancer Discov. 2021. PMID: 34301789 Free PMC article.
68 results