Gong C - Search Results

1

Integrating single cell sequencing with a spatial quantitative systems pharmacology model spQSP for personalized prediction of triple-negative breast cancer immunotherapy response.

Zhang S, Gong C, Ruiz-Martinez A, Wang H, Davis-Marcisak E, Deshpande A, Popel AS, Fertig EJ. Zhang S, et al. Among authors: gong c. Immunoinformatics (Amst). 2021 Oct;1-2:100002. doi: 10.1016/j.immuno.2021.100002. Epub 2021 Jul 24. Immunoinformatics (Amst). 2021. PMID: 34708216 Free PMC article.

2

A computational multiscale agent-based model for simulating spatio-temporal tumour immune response to PD1 and PDL1 inhibition.

Gong C, Milberg O, Wang B, Vicini P, Narwal R, Roskos L, Popel AS. Gong C, et al. J R Soc Interface. 2017 Sep;14(134):20170320. doi: 10.1098/rsif.2017.0320. J R Soc Interface. 2017. PMID: 28931635 Free PMC article.

3

Quantitative Characterization of CD8+ T Cell Clustering and Spatial Heterogeneity in Solid Tumors.

Gong C, Anders RA, Zhu Q, Taube JM, Green B, Cheng W, Bartelink IH, Vicini P, Wang B, Popel AS. Gong C, et al. Front Oncol. 2019 Jan 7;8:649. doi: 10.3389/fonc.2018.00649. eCollection 2018. Front Oncol. 2019. PMID: 30666298 Free PMC article.

4

Multiscale Agent-Based and Hybrid Modeling of the Tumor Immune Microenvironment.

Norton KA, Gong C, Jamalian S, Popel AS. Norton KA, et al. Among authors: gong c. Processes (Basel). 2019 Jan;7(1):37. doi: 10.3390/pr7010037. Epub 2019 Jan 13. Processes (Basel). 2019. PMID: 30701168 Free PMC article.

5

A Computational Model of Neoadjuvant PD-1 Inhibition in Non-Small Cell Lung Cancer.

Jafarnejad M, Gong C, Gabrielson E, Bartelink IH, Vicini P, Wang B, Narwal R, Roskos L, Popel AS. Jafarnejad M, et al. Among authors: gong c. AAPS J. 2019 Jun 24;21(5):79. doi: 10.1208/s12248-019-0350-x. AAPS J. 2019. PMID: 31236847 Free PMC article.

6

A QSP Model for Predicting Clinical Responses to Monotherapy, Combination and Sequential Therapy Following CTLA-4, PD-1, and PD-L1 Checkpoint Blockade.

Milberg O, Gong C, Jafarnejad M, Bartelink IH, Wang B, Vicini P, Narwal R, Roskos L, Popel AS. Milberg O, et al. Among authors: gong c. Sci Rep. 2019 Aug 2;9(1):11286. doi: 10.1038/s41598-019-47802-4. Sci Rep. 2019. PMID: 31375756 Free PMC article.

7

Digital Pathology Analysis Quantifies Spatial Heterogeneity of CD3, CD4, CD8, CD20, and FoxP3 Immune Markers in Triple-Negative Breast Cancer.

Mi H, Gong C, Sulam J, Fertig EJ, Szalay AS, Jaffee EM, Stearns V, Emens LA, Cimino-Mathews AM, Popel AS. Mi H, et al. Among authors: gong c. Front Physiol. 2020 Oct 19;11:583333. doi: 10.3389/fphys.2020.583333. eCollection 2020. Front Physiol. 2020. PMID: 33192595 Free PMC article.

8

A Spatial Quantitative Systems Pharmacology Platform spQSP-IO for Simulations of Tumor-Immune Interactions and Effects of Checkpoint Inhibitor Immunotherapy.

Gong C, Ruiz-Martinez A, Kimko H, Popel AS. Gong C, et al. Cancers (Basel). 2021 Jul 26;13(15):3751. doi: 10.3390/cancers13153751. Cancers (Basel). 2021. PMID: 34359653 Free PMC article.

9

Simulations of tumor growth and response to immunotherapy by coupling a spatial agent-based model with a whole-patient quantitative systems pharmacology model.

Ruiz-Martinez A, Gong C, Wang H, Sové RJ, Mi H, Kimko H, Popel AS. Ruiz-Martinez A, et al. Among authors: gong c. PLoS Comput Biol. 2022 Jul 22;18(7):e1010254. doi: 10.1371/journal.pcbi.1010254. eCollection 2022 Jul. PLoS Comput Biol. 2022. PMID: 35867773 Free PMC article.

10

Quantifying Intratumoral Heterogeneity and Immunoarchitecture Generated In-Silico by a Spatial Quantitative Systems Pharmacology Model.

Nikfar M, Mi H, Gong C, Kimko H, Popel AS. Nikfar M, et al. Among authors: gong c. Cancers (Basel). 2023 May 13;15(10):2750. doi: 10.3390/cancers15102750. Cancers (Basel). 2023. PMID: 37345087 Free PMC article.

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