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Monoclonal antibodies against metzincin targets.
Santamaria S, de Groot R. Santamaria S, et al. Among authors: de groot r. Br J Pharmacol. 2019 Jan;176(1):52-66. doi: 10.1111/bph.14186. Epub 2018 Apr 2. Br J Pharmacol. 2019. PMID: 29488211 Free PMC article. Review.
ADAMTS proteases in cardiovascular physiology and disease.
Santamaria S, de Groot R. Santamaria S, et al. Among authors: de groot r. Open Biol. 2020 Dec;10(12):200333. doi: 10.1098/rsob.200333. Epub 2020 Dec 23. Open Biol. 2020. PMID: 33352066 Free PMC article. Review.
Exosite inhibition of ADAMTS-5 by a glycoconjugated arylsulfonamide.
Santamaria S, Cuffaro D, Nuti E, Ciccone L, Tuccinardi T, Liva F, D'Andrea F, de Groot R, Rossello A, Ahnström J. Santamaria S, et al. Among authors: de groot r. Sci Rep. 2021 Jan 13;11(1):949. doi: 10.1038/s41598-020-80294-1. Sci Rep. 2021. PMID: 33441904 Free PMC article.
Development of a fluorogenic ADAMTS-7 substrate.
Santamaria S, Buemi F, Nuti E, Cuffaro D, De Vita E, Tuccinardi T, Rossello A, Howell S, Mehmood S, Snijders AP, de Groot R. Santamaria S, et al. Among authors: de vita e, de groot r. J Enzyme Inhib Med Chem. 2021 Dec;36(1):2160-2169. doi: 10.1080/14756366.2021.1983808. J Enzyme Inhib Med Chem. 2021. PMID: 34587841 Free PMC article.
Design, synthesis and biological evaluation of arylsulfonamides as ADAMTS7 inhibitors.
Cuffaro D, Burkhard T, Bernardoni BL, Di Leo R, Zhang X, Galati S, Tuccinardi T, Macchia M, Rossello A, Santamaria S, de Groot R, Nuti E. Cuffaro D, et al. Among authors: de groot r. RSC Med Chem. 2024 Jun 19;15(8):2806-2825. doi: 10.1039/d4md00149d. eCollection 2024 Aug 14. RSC Med Chem. 2024. PMID: 39149096 Free PMC article.
Cleavage of Cartilage Oligomeric Matrix Protein (COMP) by ADAMTS4 generates a neoepitope associated with osteoarthritis and other forms of degenerative joint disease.
de Groot R, Folgado PB, Yamamoto K, Martin DR, Koch CD, Debruin D, Blagg S, Minns AF, Bhutada S, Ahnström J, Larkin J, Aspberg A, Önnerfjord P, Apte SS, Santamaria S. de Groot R, et al. Matrix Biol. 2025 Feb;135:106-124. doi: 10.1016/j.matbio.2024.12.005. Epub 2024 Dec 11. Matrix Biol. 2025. PMID: 39672391 Free article.
853 results