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Commensal Cryptosporidium colonization elicits a cDC1-dependent Th1 response that promotes intestinal homeostasis and limits other infections.
Russler-Germain EV, Jung J, Miller AT, Young S, Yi J, Wehmeier A, Fox LE, Monte KJ, Chai JN, Kulkarni DH, Funkhouser-Jones LJ, Wilke G, Durai V, Zinselmeyer BH, Czepielewski RS, Greco S, Murphy KM, Newberry RD, Sibley LD, Hsieh CS. Russler-Germain EV, et al. Among authors: czepielewski rs. Immunity. 2021 Nov 9;54(11):2547-2564.e7. doi: 10.1016/j.immuni.2021.10.002. Epub 2021 Oct 28. Immunity. 2021. PMID: 34715017 Free PMC article.
Expression of factor V by resident macrophages boosts host defense in the peritoneal cavity.
Zhang N, Czepielewski RS, Jarjour NN, Erlich EC, Esaulova E, Saunders BT, Grover SP, Cleuren AC, Broze GJ, Edelson BT, Mackman N, Zinselmeyer BH, Randolph GJ. Zhang N, et al. Among authors: czepielewski rs. J Exp Med. 2019 Jun 3;216(6):1291-1300. doi: 10.1084/jem.20182024. Epub 2019 May 2. J Exp Med. 2019. PMID: 31048328 Free PMC article.
Neutrophils promote VLA-4-dependent B cell antigen presentation and accumulation within the meninges during neuroinflammation.
Parker Harp CR, Archambault AS, Cheung M, Williams JW, Czepielewski RS, Duncker PC, Kilgore AJ, Miller AT, Segal BM, Kim AHJ, Randolph GJ, Wu GF. Parker Harp CR, et al. Among authors: czepielewski rs. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24221-24230. doi: 10.1073/pnas.1909098116. Epub 2019 Nov 7. Proc Natl Acad Sci U S A. 2019. PMID: 31699814 Free PMC article.
LYVE1+ macrophages of murine peritoneal mesothelium promote omentum-independent ovarian tumor growth.
Zhang N, Kim SH, Gainullina A, Erlich EC, Onufer EJ, Kim J, Czepielewski RS, Helmink BA, Dominguez JR, Saunders BT, Ding J, Williams JW, Jiang JX, Segal BH, Zinselmeyer BH, Randolph GJ, Kim KW. Zhang N, et al. Among authors: czepielewski rs. J Exp Med. 2021 Dec 6;218(12):e20210924. doi: 10.1084/jem.20210924. Epub 2021 Oct 29. J Exp Med. 2021. PMID: 34714329 Free PMC article.
Ileitis-associated tertiary lymphoid organs arise at lymphatic valves and impede mesenteric lymph flow in response to tumor necrosis factor.
Czepielewski RS, Erlich EC, Onufer EJ, Young S, Saunders BT, Han YH, Wohltmann M, Wang PL, Kim KW, Kumar S, Hsieh CS, Scallan JP, Yang Y, Zinselmeyer BH, Davis MJ, Randolph GJ. Czepielewski RS, et al. Immunity. 2021 Dec 14;54(12):2795-2811.e9. doi: 10.1016/j.immuni.2021.10.003. Epub 2021 Nov 16. Immunity. 2021. PMID: 34788601 Free PMC article.
Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders.
Brioschi S, Wang WL, Peng V, Wang M, Shchukina I, Greenberg ZJ, Bando JK, Jaeger N, Czepielewski RS, Swain A, Mogilenko DA, Beatty WL, Bayguinov P, Fitzpatrick JAJ, Schuettpelz LG, Fronick CC, Smirnov I, Kipnis J, Shapiro VS, Wu GF, Gilfillan S, Cella M, Artyomov MN, Kleinstein SH, Colonna M. Brioschi S, et al. Among authors: czepielewski rs. Science. 2021 Jul 23;373(6553):eabf9277. doi: 10.1126/science.abf9277. Epub 2021 Jun 3. Science. 2021. PMID: 34083450 Free PMC article.
Lymph nodes go with the flow.
Czepielewski RS, Randolph GJ. Czepielewski RS, et al. J Exp Med. 2018 Nov 5;215(11):2699-2701. doi: 10.1084/jem.20181898. Epub 2018 Oct 24. J Exp Med. 2018. PMID: 30355618 Free PMC article.
30 results