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162 results

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Page 1
Opportunities and challenges related to saturation of toxicokinetic processes: Implications for risk assessment.
Tan YM, Barton HA, Boobis A, Brunner R, Clewell H, Cope R, Dawson J, Domoradzki J, Egeghy P, Gulati P, Ingle B, Kleinstreuer N, Lowe K, Lowit A, Mendez E, Miller D, Minucci J, Nguyen J, Paini A, Perron M, Phillips K, Qian H, Ramanarayanan T, Sewell F, Villanueva P, Wambaugh J, Embry M. Tan YM, et al. Among authors: kleinstreuer n. Regul Toxicol Pharmacol. 2021 Dec;127:105070. doi: 10.1016/j.yrtph.2021.105070. Epub 2021 Oct 28. Regul Toxicol Pharmacol. 2021. PMID: 34718074 Free PMC article.
Adverse outcome pathways: From research to regulation scientific workshop report.
Kleinstreuer NC, Sullivan K, Allen D, Edwards S, Mendrick DL, Embry M, Matheson J, Rowlands JC, Munn S, Maull E, Casey W. Kleinstreuer NC, et al. Regul Toxicol Pharmacol. 2016 Apr;76:39-50. doi: 10.1016/j.yrtph.2016.01.007. Epub 2016 Jan 14. Regul Toxicol Pharmacol. 2016. PMID: 26774756 Free PMC article.
Integrated decision strategies for skin sensitization hazard.
Strickland J, Zang Q, Kleinstreuer N, Paris M, Lehmann DM, Choksi N, Matheson J, Jacobs A, Lowit A, Allen D, Casey W. Strickland J, et al. Among authors: kleinstreuer n. J Appl Toxicol. 2016 Sep;36(9):1150-62. doi: 10.1002/jat.3281. Epub 2016 Feb 6. J Appl Toxicol. 2016. PMID: 26851134 Free PMC article.
Standardisation of defined approaches for skin sensitisation testing to support regulatory use and international adoption: position of the International Cooperation on Alternative Test Methods.
Casati S, Aschberger K, Barroso J, Casey W, Delgado I, Kim TS, Kleinstreuer N, Kojima H, Lee JK, Lowit A, Park HK, Régimbald-Krnel MJ, Strickland J, Whelan M, Yang Y, Zuang V. Casati S, et al. Among authors: kleinstreuer n. Arch Toxicol. 2018 Feb;92(2):611-617. doi: 10.1007/s00204-017-2097-4. Epub 2017 Nov 10. Arch Toxicol. 2018. PMID: 29127450 Free PMC article.
In vitro to in vivo extrapolation for high throughput prioritization and decision making.
Bell SM, Chang X, Wambaugh JF, Allen DG, Bartels M, Brouwer KLR, Casey WM, Choksi N, Ferguson SS, Fraczkiewicz G, Jarabek AM, Ke A, Lumen A, Lynn SG, Paini A, Price PS, Ring C, Simon TW, Sipes NS, Sprankle CS, Strickland J, Troutman J, Wetmore BA, Kleinstreuer NC. Bell SM, et al. Among authors: kleinstreuer nc. Toxicol In Vitro. 2018 Mar;47:213-227. doi: 10.1016/j.tiv.2017.11.016. Epub 2017 Dec 5. Toxicol In Vitro. 2018. PMID: 29203341 Free PMC article. Review.
Status of acute systemic toxicity testing requirements and data uses by U.S. regulatory agencies.
Strickland J, Clippinger AJ, Brown J, Allen D, Jacobs A, Matheson J, Lowit A, Reinke EN, Johnson MS, Quinn MJ Jr, Mattie D, Fitzpatrick SC, Ahir S, Kleinstreuer N, Casey W. Strickland J, et al. Among authors: kleinstreuer n. Regul Toxicol Pharmacol. 2018 Apr;94:183-196. doi: 10.1016/j.yrtph.2018.01.022. Epub 2018 Feb 3. Regul Toxicol Pharmacol. 2018. PMID: 29408321 Free PMC article. Review.
International regulatory requirements for skin sensitization testing.
Daniel AB, Strickland J, Allen D, Casati S, Zuang V, Barroso J, Whelan M, Régimbald-Krnel MJ, Kojima H, Nishikawa A, Park HK, Lee JK, Kim TS, Delgado I, Rios L, Yang Y, Wang G, Kleinstreuer N. Daniel AB, et al. Among authors: kleinstreuer n. Regul Toxicol Pharmacol. 2018 Jun;95:52-65. doi: 10.1016/j.yrtph.2018.03.003. Epub 2018 Mar 6. Regul Toxicol Pharmacol. 2018. PMID: 29518484 Free PMC article. Review.
162 results