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Opportunities and challenges related to saturation of toxicokinetic processes: Implications for risk assessment.
Tan YM, Barton HA, Boobis A, Brunner R, Clewell H, Cope R, Dawson J, Domoradzki J, Egeghy P, Gulati P, Ingle B, Kleinstreuer N, Lowe K, Lowit A, Mendez E, Miller D, Minucci J, Nguyen J, Paini A, Perron M, Phillips K, Qian H, Ramanarayanan T, Sewell F, Villanueva P, Wambaugh J, Embry M. Tan YM, et al. Among authors: nguyen j. Regul Toxicol Pharmacol. 2021 Dec;127:105070. doi: 10.1016/j.yrtph.2021.105070. Epub 2021 Oct 28. Regul Toxicol Pharmacol. 2021. PMID: 34718074 Free PMC article.
Predicting nonlinear relationships between external and internal concentrations with physiologically based pharmacokinetic modeling.
Hoer D, Barton HA, Paini A, Bartels M, Ingle B, Domoradzki J, Fisher J, Embry M, Villanueva P, Miller D, Nguyen J, Zhang Q, Edwards SW, Tan YM. Hoer D, et al. Among authors: nguyen j. Toxicol Appl Pharmacol. 2022 Apr 1;440:115922. doi: 10.1016/j.taap.2022.115922. Epub 2022 Feb 15. Toxicol Appl Pharmacol. 2022. PMID: 35176293 Free PMC article.
Differences in the pathological, transcriptomic, and prognostic implications of lymphoid structures between primary and metastatic cutaneous melanomas.
Karapetyan L, Li A, Vargas De Stefano D, Abushukair HM, Al-Bzour AN, Knight A, Layding C, Wang H, Xu J, Yao J, Song X, Joy M, Nguyen J, Moran-Segura C, Bruno S, Sander C, Messina J, Mule JJ, Storkus WJ, Kirkwood JM. Karapetyan L, et al. Among authors: nguyen j. J Immunother Cancer. 2024 Nov 12;12(11):e009231. doi: 10.1136/jitc-2024-009231. J Immunother Cancer. 2024. PMID: 39537211 Free article.
Biased activation of the vasopressin V2 receptor probed by molecular dynamics simulations, NMR and pharmacological studies.
Fouillen A, Couvineau P, Gaibelet G, Riché S, Orcel H, Mendre C, Kanso A, Lanotte R, Nguyen J, Dimon J, Urbach S, Sounier R, Granier S, Bonnet D, Cong X, Mouillac B, Déméné H. Fouillen A, et al. Among authors: nguyen j. Comput Struct Biotechnol J. 2024 Oct 24;23:3784-3799. doi: 10.1016/j.csbj.2024.10.039. eCollection 2024 Dec. Comput Struct Biotechnol J. 2024. PMID: 39525085 Free PMC article.
Seven-year performance of a clinical metagenomic next-generation sequencing test for diagnosis of central nervous system infections.
Benoit P, Brazer N, de Lorenzi-Tognon M, Kelly E, Servellita V, Oseguera M, Nguyen J, Tang J, Omura C, Streithorst J, Hillberg M, Ingebrigtsen D, Zorn K, Wilson MR, Blicharz T, Wong AP, O'Donovan B, Murray B, Miller S, Chiu CY. Benoit P, et al. Among authors: nguyen j. Nat Med. 2024 Nov 12. doi: 10.1038/s41591-024-03275-1. Online ahead of print. Nat Med. 2024. PMID: 39533109
3,508 results