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Page 1
A gp130-Src-YAP module links inflammation to epithelial regeneration.
Taniguchi K, Wu LW, Grivennikov SI, de Jong PR, Lian I, Yu FX, Wang K, Ho SB, Boland BS, Chang JT, Sandborn WJ, Hardiman G, Raz E, Maehara Y, Yoshimura A, Zucman-Rossi J, Guan KL, Karin M. Taniguchi K, et al. Among authors: chang jt. Nature. 2015 Mar 5;519(7541):57-62. doi: 10.1038/nature14228. Epub 2015 Feb 25. Nature. 2015. PMID: 25731159 Free PMC article.
Proteasome activity regulates CD8+ T lymphocyte metabolism and fate specification.
Widjaja CE, Olvera JG, Metz PJ, Phan AT, Savas JN, de Bruin G, Leestemaker Y, Berkers CR, de Jong A, Florea BI, Fisch K, Lopez J, Kim SH, Garcia DA, Searles S, Bui JD, Chang AN, Yates JR 3rd, Goldrath AW, Overkleeft HS, Ovaa H, Chang JT. Widjaja CE, et al. Among authors: chang an, chang jt. J Clin Invest. 2017 Oct 2;127(10):3609-3623. doi: 10.1172/JCI90895. Epub 2017 Aug 28. J Clin Invest. 2017. PMID: 28846070 Free PMC article.
Integrin Activation Controls Regulatory T Cell-Mediated Peripheral Tolerance.
Klann JE, Kim SH, Remedios KA, He Z, Metz PJ, Lopez J, Tysl T, Olvera JG, Ablack JN, Cantor JM, Boland BS, Yeo G, Zheng Y, Lu LF, Bui JD, Ginsberg MH, Petrich BG, Chang JT. Klann JE, et al. Among authors: chang jt. J Immunol. 2018 Jun 15;200(12):4012-4023. doi: 10.4049/jimmunol.1800112. Epub 2018 Apr 27. J Immunol. 2018. PMID: 29703862 Free PMC article.
Global chemical effects of the microbiome include new bile-acid conjugations.
Quinn RA, Melnik AV, Vrbanac A, Fu T, Patras KA, Christy MP, Bodai Z, Belda-Ferre P, Tripathi A, Chung LK, Downes M, Welch RD, Quinn M, Humphrey G, Panitchpakdi M, Weldon KC, Aksenov A, da Silva R, Avila-Pacheco J, Clish C, Bae S, Mallick H, Franzosa EA, Lloyd-Price J, Bussell R, Thron T, Nelson AT, Wang M, Leszczynski E, Vargas F, Gauglitz JM, Meehan MJ, Gentry E, Arthur TD, Komor AC, Poulsen O, Boland BS, Chang JT, Sandborn WJ, Lim M, Garg N, Lumeng JC, Xavier RJ, Kazmierczak BI, Jain R, Egan M, Rhee KE, Ferguson D, Raffatellu M, Vlamakis H, Haddad GG, Siegel D, Huttenhower C, Mazmanian SK, Evans RM, Nizet V, Knight R, Dorrestein PC. Quinn RA, et al. Among authors: chang jt. Nature. 2020 Mar;579(7797):123-129. doi: 10.1038/s41586-020-2047-9. Epub 2020 Feb 26. Nature. 2020. PMID: 32103176 Free PMC article.
Early precursors and molecular determinants of tissue-resident memory CD8+ T lymphocytes revealed by single-cell RNA sequencing.
Kurd NS, He Z, Louis TL, Milner JJ, Omilusik KD, Jin W, Tsai MS, Widjaja CE, Kanbar JN, Olvera JG, Tysl T, Quezada LK, Boland BS, Huang WJ, Murre C, Goldrath AW, Yeo GW, Chang JT. Kurd NS, et al. Among authors: chang jt. Sci Immunol. 2020 May 15;5(47):eaaz6894. doi: 10.1126/sciimmunol.aaz6894. Sci Immunol. 2020. PMID: 32414833 Free PMC article.
Heterogeneity and clonal relationships of adaptive immune cells in ulcerative colitis revealed by single-cell analyses.
Boland BS, He Z, Tsai MS, Olvera JG, Omilusik KD, Duong HG, Kim ES, Limary AE, Jin W, Milner JJ, Yu B, Patel SA, Louis TL, Tysl T, Kurd NS, Bortnick A, Quezada LK, Kanbar JN, Miralles A, Huylebroeck D, Valasek MA, Dulai PS, Singh S, Lu LF, Bui JD, Murre C, Sandborn WJ, Goldrath AW, Yeo GW, Chang JT. Boland BS, et al. Among authors: chang jt. Sci Immunol. 2020 Aug 21;5(50):eabb4432. doi: 10.1126/sciimmunol.abb4432. Sci Immunol. 2020. PMID: 32826341 Free PMC article.
The Host-Microbiome Response to Hyperbaric Oxygen Therapy in Ulcerative Colitis Patients.
Gonzalez CG, Mills RH, Kordahi MC, Carrillo-Terrazas M, Secaira-Morocho H, Widjaja CE, Tsai MS, Mittal Y, Yee BA, Vargas F, Weldon K, Gauglitz JM, Delaroque C, Sauceda C, Rossitto LA, Ackermann G, Humphrey G, Swafford AD, Siegel CA, Buckey JC Jr, Raffals LE, Sadler C, Lindholm P, Fisch KM, Valaseck M, Suriawinata A, Yeo GW, Ghosh P, Chang JT, Chu H, Dorrestein P, Zhu Q, Chassaing B, Knight R, Gonzalez DJ, Dulai PS. Gonzalez CG, et al. Among authors: chang jt. Cell Mol Gastroenterol Hepatol. 2022;14(1):35-53. doi: 10.1016/j.jcmgh.2022.03.008. Epub 2022 Apr 1. Cell Mol Gastroenterol Hepatol. 2022. PMID: 35378331 Free PMC article.
Small intestine and colon tissue-resident memory CD8+ T cells exhibit molecular heterogeneity and differential dependence on Eomes.
Lin YH, Duong HG, Limary AE, Kim ES, Hsu P, Patel SA, Wong WH, Indralingam CS, Liu YC, Yao P, Chiang NR, Vandenburgh SA, Anderson TR, Olvera JG, Ferry A, Takehara KK, Jin W, Tsai MS, Yeo GW, Goldrath AW, Chang JT. Lin YH, et al. Among authors: chang jt. Immunity. 2023 Jan 10;56(1):207-223.e8. doi: 10.1016/j.immuni.2022.12.007. Epub 2022 Dec 28. Immunity. 2023. PMID: 36580919 Free PMC article.
Identification of CD8 + T-Cell-Immune Cell Communications in Ileal Crohn's Disease.
Duong HG, Choi EJ, Hsu P, Chiang NR, Patel SA, Olvera JG, Liu YC, Lin YH, Yao P, Wong WH, Indralingam CS, Tsai MS, Boland BS, Wang W, Chang JT. Duong HG, et al. Among authors: chang jt. Clin Transl Gastroenterol. 2023 May 1;14(5):e00576. doi: 10.14309/ctg.0000000000000576. Clin Transl Gastroenterol. 2023. PMID: 36854061 Free PMC article.
743 results