El-Khoury D - Search Results

1

The histone demethylase Lsd1 regulates multiple repressive gene programs during T cell development.

Stamos DB, Clubb LM, Mitra A, Chopp LB, Nie J, Ding Y, Das A, Venkataganesh H, Lee J, El-Khoury D, Li L, Bhandoola A, Bosselut R, Love PE. Stamos DB, et al. Among authors: el khoury d. J Exp Med. 2021 Dec 6;218(12):e20202012. doi: 10.1084/jem.20202012. Epub 2021 Nov 2. J Exp Med. 2021. PMID: 34726730 Free PMC article.

2

Reduced TCR signaling potential impairs negative selection but does not result in autoimmune disease.

Hwang S, Song KD, Lesourne R, Lee J, Pinkhasov J, Li L, El-Khoury D, Love PE. Hwang S, et al. J Exp Med. 2012 Sep 24;209(10):1781-95. doi: 10.1084/jem.20120058. Epub 2012 Sep 3. J Exp Med. 2012. PMID: 22945921 Free PMC article.

3

Activation-induced modification in the CD3 complex of the gammadelta T cell receptor.

Hayes SM, Laky K, El-Khoury D, Kappes DJ, Fowlkes BJ, Love PE. Hayes SM, et al. J Exp Med. 2002 Nov 18;196(10):1355-61. doi: 10.1084/jem.20021196. J Exp Med. 2002. PMID: 12438426 Free PMC article.

4

Mutation of the phospholipase C-gamma1-binding site of LAT affects both positive and negative thymocyte selection.

Sommers CL, Lee J, Steiner KL, Gurson JM, Depersis CL, El-Khoury D, Fuller CL, Shores EW, Love PE, Samelson LE. Sommers CL, et al. J Exp Med. 2005 Apr 4;201(7):1125-34. doi: 10.1084/jem.20041869. Epub 2005 Mar 28. J Exp Med. 2005. PMID: 15795236 Free PMC article.

5

In vivo functional mapping of the conserved protein domains within murine Themis1.

Zvezdova E, Lee J, El-Khoury D, Barr V, Akpan I, Samelson L, Love PE. Zvezdova E, et al. Immunol Cell Biol. 2014 Sep;92(8):721-8. doi: 10.1038/icb.2014.43. Epub 2014 Jun 17. Immunol Cell Biol. 2014. PMID: 24935457 Free PMC article.

6

Ldb1 is required for Lmo2 oncogene-induced thymocyte self-renewal and T-cell acute lymphoblastic leukemia.

Li L, Mitra A, Cui K, Zhao B, Choi S, Lee JY, Stamos DB, El-Khoury D, Warzecha C, Pfeifer K, Hardwick J, Zhao K, Venters B, Davé UP, Love PE. Li L, et al. Blood. 2020 Jun 18;135(25):2252-2265. doi: 10.1182/blood.2019000794. Blood. 2020. PMID: 32181817 Free PMC article.

7

Function of CD3 epsilon-mediated signals in T cell development.

Sommers CL, Dejarnette JB, Huang K, Lee J, El-Khoury D, Shores EW, Love PE. Sommers CL, et al. J Exp Med. 2000 Sep 18;192(6):913-19. doi: 10.1084/jem.192.6.913. J Exp Med. 2000. PMID: 10993922 Free PMC article.

8

Premature expression of chemokine receptor CCR9 impairs T cell development.

Uehara S, Hayes SM, Li L, El-Khoury D, Canelles M, Fowlkes BJ, Love PE. Uehara S, et al. J Immunol. 2006 Jan 1;176(1):75-84. doi: 10.4049/jimmunol.176.1.75. J Immunol. 2006. PMID: 16365398

9

A potential role for CD69 in thymocyte emigration.

Feng C, Woodside KJ, Vance BA, El-Khoury D, Canelles M, Lee J, Gress R, Fowlkes BJ, Shores EW, Love PE. Feng C, et al. Int Immunol. 2002 Jun;14(6):535-44. doi: 10.1093/intimm/dxf020. Int Immunol. 2002. PMID: 12039905

10

Interchangeability of Themis1 and Themis2 in thymocyte development reveals two related proteins with conserved molecular function.

Lesourne R, Zvezdova E, Song KD, El-Khoury D, Uehara S, Barr VA, Samelson LE, Love PE. Lesourne R, et al. J Immunol. 2012 Aug 1;189(3):1154-61. doi: 10.4049/jimmunol.1200123. Epub 2012 Jun 25. J Immunol. 2012. PMID: 22732588 Free PMC article.

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