Cubberley R - Search Results

1

A hypothetical skin sensitisation next generation risk assessment for coumarin in cosmetic products.

Reynolds G, Reynolds J, Gilmour N, Cubberley R, Spriggs S, Aptula A, Przybylak K, Windebank S, Maxwell G, Baltazar MT. Reynolds G, et al. Among authors: cubberley r. Regul Toxicol Pharmacol. 2021 Dec;127:105075. doi: 10.1016/j.yrtph.2021.105075. Epub 2021 Oct 30. Regul Toxicol Pharmacol. 2021. PMID: 34728330 Free article.

2

Applying the skin sensitisation adverse outcome pathway (AOP) to quantitative risk assessment.

Maxwell G, MacKay C, Cubberley R, Davies M, Gellatly N, Glavin S, Gouin T, Jacquoilleot S, Moore C, Pendlington R, Saib O, Sheffield D, Stark R, Summerfield V. Maxwell G, et al. Among authors: cubberley r. Toxicol In Vitro. 2014 Feb;28(1):8-12. doi: 10.1016/j.tiv.2013.10.013. Epub 2013 Oct 31. Toxicol In Vitro. 2014. PMID: 24184331

3

A study of inter-individual variability in the Phase II metabolism of xenobiotics in human skin.

Spriggs S, Cubberley R, Loadman P, Sheffield D, Wierzbicki A. Spriggs S, et al. Among authors: cubberley r. Toxicol Lett. 2018 Aug;292:63-72. doi: 10.1016/j.toxlet.2018.04.011. Epub 2018 Apr 27. Toxicol Lett. 2018. PMID: 29709425

4

Proteomic analysis of haptenation by skin sensitisers: Diphencyprone and ethyl acrylate.

Parkinson E, Aleksic M, Arthur R, Regufe Da Mota S, Cubberley R, Skipp PJ. Parkinson E, et al. Among authors: cubberley r. Toxicol In Vitro. 2020 Feb;62:104697. doi: 10.1016/j.tiv.2019.104697. Epub 2019 Oct 24. Toxicol In Vitro. 2020. PMID: 31669365

5

A Next-Generation Risk Assessment Case Study for Coumarin in Cosmetic Products.

Baltazar MT, Cable S, Carmichael PL, Cubberley R, Cull T, Delagrange M, Dent MP, Hatherell S, Houghton J, Kukic P, Li H, Lee MY, Malcomber S, Middleton AM, Moxon TE, Nathanail AV, Nicol B, Pendlington R, Reynolds G, Reynolds J, White A, Westmoreland C. Baltazar MT, et al. Among authors: cubberley r. Toxicol Sci. 2020 Jul 1;176(1):236-252. doi: 10.1093/toxsci/kfaa048. Toxicol Sci. 2020. PMID: 32275751 Free PMC article.

6

Proteomic analysis of the cellular response to a potent sensitiser unveils the dynamics of haptenation in living cells.

Parkinson E, Aleksic M, Kukic P, Bailey A, Cubberley R, Skipp P. Parkinson E, et al. Among authors: cubberley r. Toxicology. 2020 Dec 1;445:152603. doi: 10.1016/j.tox.2020.152603. Epub 2020 Sep 28. Toxicology. 2020. PMID: 32991956 Free article.

7

Next generation risk assessment for skin allergy: Decision making using new approach methodologies.

Gilmour N, Reynolds J, Przybylak K, Aleksic M, Aptula N, Baltazar MT, Cubberley R, Rajagopal R, Reynolds G, Spriggs S, Thorpe C, Windebank S, Maxwell G. Gilmour N, et al. Among authors: cubberley r. Regul Toxicol Pharmacol. 2022 Jun;131:105159. doi: 10.1016/j.yrtph.2022.105159. Epub 2022 Mar 17. Regul Toxicol Pharmacol. 2022. PMID: 35311660

8

PBK modelling of topical application and characterisation of the uncertainty of C_max estimate: A case study approach.

Li H, Reynolds J, Sorrell I, Sheffield D, Pendlington R, Cubberley R, Nicol B. Li H, et al. Among authors: cubberley r. Toxicol Appl Pharmacol. 2022 May 1;442:115992. doi: 10.1016/j.taap.2022.115992. Epub 2022 Mar 25. Toxicol Appl Pharmacol. 2022. PMID: 35346730 Free article.

9

ADME characterization and PBK model development of 3 highly protein-bound UV filters through topical application.

Li H, Bunglawala F, Hewitt NJ, Pendlington R, Cubberley R, Nicol B, Spriggs S, Baltazar M, Cable S, Dent M. Li H, et al. Among authors: cubberley r. Toxicol Sci. 2023 Oct 30;196(1):1-15. doi: 10.1093/toxsci/kfad081. Toxicol Sci. 2023. PMID: 37584694 Free PMC article.

10

Development of a human liver microphysiological coculture system for higher throughput chemical safety assessment.

Ip BC, Madnick SJ, Zheng S, van Tongeren TCA, Hall SJ, Li H, Martin S, Spriggs S, Carmichael P, Chen W, Ames D, Breitweiser LA, Pence HE, Bowling AJ, Johnson KJ, Cubberley R, Morgan JR, Boekelheide K. Ip BC, et al. Among authors: cubberley r. Toxicol Sci. 2024 May 28;199(2):227-245. doi: 10.1093/toxsci/kfae018. Toxicol Sci. 2024. PMID: 38335931

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