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Dystrophin and mini-dystrophin quantification by mass spectrometry in skeletal muscle for gene therapy development in Duchenne muscular dystrophy.
Farrokhi V, Walsh J, Palandra J, Brodfuehrer J, Caiazzo T, Owens J, Binks M, Neelakantan S, Yong F, Dua P, Le Guiner C, Neubert H. Farrokhi V, et al. Among authors: dua p. Gene Ther. 2022 Nov;29(10-11):608-615. doi: 10.1038/s41434-021-00300-7. Epub 2021 Nov 5. Gene Ther. 2022. PMID: 34737451 Free PMC article.
Pharmacology in translation: the preclinical and early clinical profile of the novel α2/3 functionally selective GABAA receptor positive allosteric modulator PF-06372865.
Nickolls SA, Gurrell R, van Amerongen G, Kammonen J, Cao L, Brown AR, Stead C, Mead A, Watson C, Hsu C, Owen RM, Pike A, Fish RL, Chen L, Qiu R, Morris ED, Feng G, Whitlock M, Gorman D, van Gerven J, Reynolds DS, Dua P, Butt RP. Nickolls SA, et al. Among authors: dua p. Br J Pharmacol. 2018 Feb;175(4):708-725. doi: 10.1111/bph.14119. Epub 2018 Jan 18. Br J Pharmacol. 2018. PMID: 29214652 Free PMC article. Clinical Trial.
An 8-Week, Randomized, Phase 2, Double-Blind, Sequential Parallel-Group Comparison Study of Two Dose Levels of the GABAA Positive Allosteric Modulator PF-06372865 Compared With Placebo as an Adjunctive Treatment in Outpatients With Inadequate Response to Standard of Care for Generalized Anxiety Disorder.
Simen A, Whitlock M, Qiu R, Miceli J, Zumpano L, Du Metz M, Dua P, Binneman B. Simen A, et al. Among authors: dua p. J Clin Psychopharmacol. 2019 Jan/Feb;39(1):20-27. doi: 10.1097/JCP.0000000000000997. J Clin Psychopharmacol. 2019. PMID: 30531477 Clinical Trial.
Phase I study of PF‐04895162, a Kv7 channel opener, reveals unexpected hepatotoxicity in healthy subjects, but not rats or monkeys: clinical evidence of disrupted bile acid homeostasis.
Aleo MD, Aubrecht J, D Bonin P, Burt DA, Colangelo J, Luo L, Schomaker S, Swiss R, Kirby S, C Rigdon G, Dua P. Aleo MD, et al. Among authors: dua p. Pharmacol Res Perspect. 2019 Feb;7(1):e00467. doi: 10.1002/prp2.467. Pharmacol Res Perspect. 2019. PMID: 30784208 Free PMC article. Clinical Trial.
A Tutorial on Target-Mediated Drug Disposition (TMDD) Models.
Dua P, Hawkins E, van der Graaf PH. Dua P, et al. CPT Pharmacometrics Syst Pharmacol. 2015 Jun;4(6):324-37. doi: 10.1002/psp4.41. Epub 2015 Jun 15. CPT Pharmacometrics Syst Pharmacol. 2015. PMID: 26225261 Free PMC article.
Physiology of Hyperuricemia and Urate-Lowering Treatments.
Benn CL, Dua P, Gurrell R, Loudon P, Pike A, Storer RI, Vangjeli C. Benn CL, et al. Among authors: dua p. Front Med (Lausanne). 2018 May 31;5:160. doi: 10.3389/fmed.2018.00160. eCollection 2018. Front Med (Lausanne). 2018. PMID: 29904633 Free PMC article. Review.
147 results