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Antibody-peptide conjugates deliver covalent inhibitors blocking oncogenic cathepsins.
Petruzzella A, Bruand M, Santamaria-Martínez A, Katanayeva N, Reymond L, Wehrle S, Georgeon S, Inel D, van Dalen FJ, Viertl D, Lau K, Pojer F, Schottelius M, Zoete V, Verdoes M, Arber C, Correia BE, Oricchio E. Petruzzella A, et al. Among authors: inel d. Nat Chem Biol. 2024 Sep;20(9):1188-1198. doi: 10.1038/s41589-024-01627-z. Epub 2024 May 29. Nat Chem Biol. 2024. PMID: 38811854
Contextual reprogramming of CAR-T cells for treatment of HER2+ cancers.
Yang Z, Li L, Turkoz A, Chen P, Harari-Steinfeld R, Bobbin M, Stefanson O, Choi H, Pietrobon V, Alphson B, Goswami A, Balan V, Kearney A, Patel D, Yang J, Inel D, Vinod V, Cesano A, Wang B, Roh KH, Qi LS, Marincola FM. Yang Z, et al. Among authors: inel d. J Transl Med. 2021 Nov 7;19(1):459. doi: 10.1186/s12967-021-03132-6. J Transl Med. 2021. PMID: 34743703 Free PMC article.