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Chemically Synthesized Alcaligenes Lipid A as an Adjuvant to Augment Immune Responses to Haemophilus Influenzae Type B Conjugate Vaccine.
Liu Z, Hosomi K, Shimoyama A, Yoshii K, Sun X, Lan H, Wang Y, Yamaura H, Kenneth D, Saika A, Nagatake T, Kiyono H, Fukase K, Kunisawa J. Liu Z, et al. Among authors: yoshii k. Front Pharmacol. 2021 Oct 22;12:763657. doi: 10.3389/fphar.2021.763657. eCollection 2021. Front Pharmacol. 2021. PMID: 34744743 Free PMC article.
Adjuvant Activity of Synthetic Lipid A of Alcaligenes, a Gut-Associated Lymphoid Tissue-Resident Commensal Bacterium, to Augment Antigen-Specific IgG and Th17 Responses in Systemic Vaccine.
Wang Y, Hosomi K, Shimoyama A, Yoshii K, Yamaura H, Nagatake T, Nishino T, Kiyono H, Fukase K, Kunisawa J. Wang Y, et al. Among authors: yoshii k. Vaccines (Basel). 2020 Jul 20;8(3):395. doi: 10.3390/vaccines8030395. Vaccines (Basel). 2020. PMID: 32698404 Free PMC article.
Lipopolysaccharide Derived From the Lymphoid-Resident Commensal Bacteria Alcaligenes faecalis Functions as an Effective Nasal Adjuvant to Augment IgA Antibody and Th17 Cell Responses.
Wang Y, Hosomi K, Shimoyama A, Yoshii K, Nagatake T, Fujimoto Y, Kiyono H, Fukase K, Kunisawa J. Wang Y, et al. Among authors: yoshii k. Front Immunol. 2021 Jul 1;12:699349. doi: 10.3389/fimmu.2021.699349. eCollection 2021. Front Immunol. 2021. PMID: 34276692 Free PMC article.
TLR4 agonist activity of Alcaligenes lipid a utilizes MyD88 and TRIF signaling pathways for efficient antigen presentation and T cell differentiation by dendritic cells.
Sun X, Hosomi K, Shimoyama A, Yoshii K, Lan H, Wang Y, Yamaura H, Nagatake T, Ishii KJ, Akira S, Kiyono H, Fukase K, Kunisawa J. Sun X, et al. Among authors: yoshii k. Int Immunopharmacol. 2023 Apr;117:109852. doi: 10.1016/j.intimp.2023.109852. Epub 2023 Feb 18. Int Immunopharmacol. 2023. PMID: 36806039 Free article.
QcrC is a potential target for antibody therapy and vaccination to control Campylobacter jejuni infection by suppressing its energy metabolism.
Hosomi K, Hatanaka N, Hinenoya A, Adachi J, Tojima Y, Furuta M, Uchiyama K, Morita M, Nagatake T, Saika A, Kawai S, Yoshii K, Kondo S, Yamasaki S, Kunisawa J. Hosomi K, et al. Among authors: yoshii k. Front Microbiol. 2024 Jul 2;15:1415893. doi: 10.3389/fmicb.2024.1415893. eCollection 2024. Front Microbiol. 2024. PMID: 39015740 Free PMC article.
448 results