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Inhibition of FGFR Reactivates IFNγ Signaling in Tumor Cells to Enhance the Combined Antitumor Activity of Lenvatinib with Anti-PD-1 Antibodies.
Adachi Y, Kamiyama H, Ichikawa K, Fukushima S, Ozawa Y, Yamaguchi S, Goda S, Kimura T, Kodama K, Matsuki M, Miyano SW, Yokoi A, Kato Y, Funahashi Y. Adachi Y, et al. Among authors: ichikawa k. Cancer Res. 2022 Jan 15;82(2):292-306. doi: 10.1158/0008-5472.CAN-20-2426. Epub 2021 Nov 9. Cancer Res. 2022. PMID: 34753772 Free PMC article.
Discovery of a potent and selective Axl inhibitor in preclinical model.
Inoue S, Yamane Y, Tsukamoto S, Azuma H, Nagao S, Murai N, Nishibata K, Fukushima S, Ichikawa K, Nakagawa T, Hata Sugi N, Ito D, Kato Y, Goto A, Kakiuchi D, Ueno T, Matsui J, Matsushima T. Inoue S, et al. Among authors: ichikawa k. Bioorg Med Chem. 2021 Jun 1;39:116137. doi: 10.1016/j.bmc.2021.116137. Epub 2021 Apr 21. Bioorg Med Chem. 2021. PMID: 33930844
Discovery of 5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine derivatives as novel selective Axl inhibitors.
Inoue S, Yamane Y, Tsukamoto S, Murai N, Azuma H, Nagao S, Nishibata K, Fukushima S, Ichikawa K, Nakagawa T, Hata Sugi N, Ito D, Kato Y, Goto A, Kakiuchi D, Ueno T, Matsui J, Matsushima T. Inoue S, et al. Among authors: ichikawa k. Bioorg Med Chem Lett. 2021 Sep 15;48:128247. doi: 10.1016/j.bmcl.2021.128247. Epub 2021 Jul 13. Bioorg Med Chem Lett. 2021. PMID: 34271070
ER-851, a Novel Selective Inhibitor of AXL, Overcomes Resistance to Antimitotic Drugs.
Tsukamoto S, Sugi NH, Nishibata K, Nakazawa Y, Ito D, Fukushima S, Nakagawa T, Ichikawa K, Kato Y, Kakiuchi D, Goto A, Itoh-Yagi M, Aota T, Inoue S, Yamane Y, Murai N, Azuma H, Nagao S, Sasai K, Akagi T, Imai T, Matsui J, Matsushima T. Tsukamoto S, et al. Among authors: ichikawa k. Mol Cancer Ther. 2023 Jan 3;22(1):12-24. doi: 10.1158/1535-7163.MCT-21-0879. Mol Cancer Ther. 2023. PMID: 36279567
Discovery of FHD-286, a First-in-Class, Orally Bioavailable, Allosteric Dual Inhibitor of the Brahma Homologue (BRM) and Brahma-Related Gene 1 (BRG1) ATPase Activity for the Treatment of SWItch/Sucrose Non-Fermentable (SWI/SNF) Dependent Cancers.
Vaswani RG, Huang DS, Anthony N, Xu L, Centore R, Schiller S, Li Z, Fan H, Setser J, Zawadzke LE, Davenport Y, Chen X, Barnash K, Adam A, Ichikawa K, Huang L, Gu CH, Voigt J, Millan D, Chan HM, Decicco C, Hentemann M, Bellon SF, Wilson KJ. Vaswani RG, et al. Among authors: ichikawa k. J Med Chem. 2025 Jan 12. doi: 10.1021/acs.jmedchem.4c02535. Online ahead of print. J Med Chem. 2025. PMID: 39801091
Ultrasound-Guided Repair of the Anterior Talofibular Ligament With or Without Gould Augmentation Is Safe and Improves Clinical Outcomes for Chronic Lateral Ankle Instability: A Case Series of 49 Patients.
Hattori S, Onishi K, Okada T, Umanes MM, Ichikawa K, Takazawa S, Yamada S, Kato Y, Hogan MV, Ohuchi H. Hattori S, et al. Among authors: ichikawa k. J ISAKOS. 2025 Jan 9:100386. doi: 10.1016/j.jisako.2025.100386. Online ahead of print. J ISAKOS. 2025. PMID: 39798604
1,514 results