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Leveraging machine learning essentiality predictions and chemogenomic interactions to identify antifungal targets.
Fu C, Zhang X, Veri AO, Iyer KR, Lash E, Xue A, Yan H, Revie NM, Wong C, Lin ZY, Polvi EJ, Liston SD, VanderSluis B, Hou J, Yashiroda Y, Gingras AC, Boone C, O'Meara TR, O'Meara MJ, Noble S, Robbins N, Myers CL, Cowen LE. Fu C, et al. Among authors: hou j. Nat Commun. 2021 Nov 11;12(1):6497. doi: 10.1038/s41467-021-26850-3. Nat Commun. 2021. PMID: 34764269 Free PMC article.
Complex modifier landscape underlying genetic background effects.
Hou J, Tan G, Fink GR, Andrews BJ, Boone C. Hou J, et al. Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):5045-5054. doi: 10.1073/pnas.1820915116. Epub 2019 Feb 25. Proc Natl Acad Sci U S A. 2019. PMID: 30804202 Free PMC article.
Systematic analysis of bypass suppression of essential genes.
van Leeuwen J, Pons C, Tan G, Wang ZY, Hou J, Weile J, Gebbia M, Liang W, Shuteriqi E, Li Z, Lopes M, Ušaj M, Dos Santos Lopes A, van Lieshout N, Myers CL, Roth FP, Aloy P, Andrews BJ, Boone C. van Leeuwen J, et al. Among authors: hou j. Mol Syst Biol. 2020 Sep;16(9):e9828. doi: 10.15252/msb.20209828. Mol Syst Biol. 2020. PMID: 32939983 Free PMC article.
Environmental robustness of the global yeast genetic interaction network.
Costanzo M, Hou J, Messier V, Nelson J, Rahman M, VanderSluis B, Wang W, Pons C, Ross C, Ušaj M, San Luis BJ, Shuteriqi E, Koch EN, Aloy P, Myers CL, Boone C, Andrews B. Costanzo M, et al. Among authors: hou j. Science. 2021 May 7;372(6542):eabf8424. doi: 10.1126/science.abf8424. Science. 2021. PMID: 33958448 Free PMC article.
11,030 results
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