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Non-Native Amino Acid Click Chemistry-Based Technology for Site-Specific Polysaccharide Conjugation to a Bacterial Protein Serving as Both Carrier and Vaccine Antigen.
Kapoor N, Uchiyama S, Pill L, Bautista L, Sedra A, Yin L, Regan M, Chu E, Rabara T, Wong M, Davey P, Fairman J, Nizet V. Kapoor N, et al. Among authors: fairman j. ACS Omega. 2022 Jul 11;7(28):24111-24120. doi: 10.1021/acsomega.1c07360. eCollection 2022 Jul 19. ACS Omega. 2022. PMID: 35874267 Free PMC article.
Addition of Lauryldimethylamine N-Oxide (LDAO) to a Copper-Free Click Chemistry Reaction Improves the Conjugation Efficiency of a Cell-Free Generated CRM197 Variant to Clinically Important Streptococcus pneumoniae Serotypes.
Bautista L, Pill-Pepe L, Kapoor N, Snyder S, Chu E, Agarwal P, Sardar M, Arulkumar S, Berges A, Iverson M, Behrens C, Marcq O, Fairman J. Bautista L, et al. Among authors: fairman j. ACS Omega. 2022 Sep 20;7(39):34921-34928. doi: 10.1021/acsomega.2c03481. eCollection 2022 Oct 4. ACS Omega. 2022. PMID: 36211053 Free PMC article.
Non-clinical immunological comparison of a Next-Generation 24-valent pneumococcal conjugate vaccine (VAX-24) using site-specific carrier protein conjugation to the current standard of care (PCV13 and PPV23).
Fairman J, Agarwal P, Barbanel S, Behrens C, Berges A, Burky J, Davey P, Fernsten P, Grainger C, Guo S, Iki S, Iverson M, Kane M, Kapoor N, Marcq O, Migone TS, Sauer P, Wassil J. Fairman J, et al. Vaccine. 2021 May 27;39(23):3197-3206. doi: 10.1016/j.vaccine.2021.03.070. Epub 2021 May 6. Vaccine. 2021. PMID: 33965258 Free article.
160 results