Chen YM - Search Results

1

Hippocampal MSK1 regulates the behavioral and biological responses of mice to chronic social defeat stress: Involving of the BDNF-CREB signaling and neurogenesis.

Ji CH, Gu JH, Liu Y, Tang WQ, Guan W, Huang J, Chen YM, Xu DW, Jiang B. Ji CH, et al. Among authors: chen ym. Biochem Pharmacol. 2022 Jan;195:114836. doi: 10.1016/j.bcp.2021.114836. Epub 2021 Nov 11. Biochem Pharmacol. 2022. PMID: 34774532

2

The Selective SIK2 Inhibitor ARN-3236 Produces Strong Antidepressant-Like Efficacy in Mice via the Hippocampal CRTC1-CREB-BDNF Pathway.

Liu Y, Tang W, Ji C, Gu J, Chen Y, Huang J, Zhao X, Sun Y, Wang C, Guan W, Liu J, Jiang B. Liu Y, et al. Front Pharmacol. 2021 Jan 14;11:624429. doi: 10.3389/fphar.2020.624429. eCollection 2020. Front Pharmacol. 2021. PMID: 33519490 Free PMC article.

3

Hippocampal miR-206-3p participates in the pathogenesis of depression via regulating the expression of BDNF.

Guan W, Xu DW, Ji CH, Wang CN, Liu Y, Tang WQ, Gu JH, Chen YM, Huang J, Liu JF, Jiang B. Guan W, et al. Among authors: chen ym. Pharmacol Res. 2021 Dec;174:105932. doi: 10.1016/j.phrs.2021.105932. Epub 2021 Oct 8. Pharmacol Res. 2021. PMID: 34628001

4

Virus-mediated decrease of LKB1 activity in the mPFC diminishes stress-induced depressive-like behaviors in mice.

Tang WQ, Liu Y, Ji CH, Gu JH, Chen YM, Huang J, Guan W, Xu DW, Jiang B. Tang WQ, et al. Among authors: chen ym. Biochem Pharmacol. 2022 Mar;197:114885. doi: 10.1016/j.bcp.2021.114885. Epub 2021 Dec 27. Biochem Pharmacol. 2022. PMID: 34968488

5

Hippocampal F3/Contactin plays a role in chronic stress-induced depressive-like effects and the antidepressant actions of vortioxetine in mice.

Chen YM, Fan H, Huang J, Shi TS, Li WY, Wang CN, Jiang B, Liu JF. Chen YM, et al. Biochem Pharmacol. 2022 Aug;202:115097. doi: 10.1016/j.bcp.2022.115097. Epub 2022 May 21. Biochem Pharmacol. 2022. PMID: 35609645

6

Salt-inducible kinase 1-CREB-regulated transcription coactivator 1 signalling in the paraventricular nucleus of the hypothalamus plays a role in depression by regulating the hypothalamic-pituitary-adrenal axis.

Wang Y, Liu L, Gu JH, Wang CN, Guan W, Liu Y, Tang WQ, Ji CH, Chen YM, Huang J, Li WY, Shi TS, Chen WJ, Zhu BL, Jiang B. Wang Y, et al. Among authors: chen ym, chen wj. Mol Psychiatry. 2024 Jun;29(6):1660-1670. doi: 10.1038/s41380-022-01881-4. Epub 2022 Nov 25. Mol Psychiatry. 2024. PMID: 36434056

7

The salt-inducible kinases inhibitor HG-9-91-01 exhibits antidepressant-like actions in mice exposed to chronic unpredictable mild stress.

Huang J, Fan H, Chen YM, Wang CN, Guan W, Li WY, Shi TS, Chen WJ, Zhu BL, Liu JF, Jiang B. Huang J, et al. Among authors: chen ym, chen wj. Neuropharmacology. 2023 Apr 1;227:109437. doi: 10.1016/j.neuropharm.2023.109437. Epub 2023 Jan 23. Neuropharmacology. 2023. PMID: 36702294

8

Activation of mTORC1 Signaling Cascade in Hippocampus and Medial Prefrontal Cortex Is Required for Antidepressant Actions of Vortioxetine in Mice.

Li WY, Shi TS, Huang J, Chen YM, Guan W, Jiang B, Wang CN. Li WY, et al. Among authors: chen ym. Int J Neuropsychopharmacol. 2023 Oct 19;26(10):655-668. doi: 10.1093/ijnp/pyad017. Int J Neuropsychopharmacol. 2023. PMID: 37025079 Free PMC article.

9

The antidepressant-like effects of escitalopram in mice require salt-inducible kinase 1 and CREB-regulated transcription co-activator 1 in the paraventricular nucleus of the hypothalamus.

Shi TS, Li WY, Chen YM, Huang J, Guan W, Xu DW, Jiang B. Shi TS, et al. Among authors: chen ym. J Affect Disord. 2023 Oct 1;338:228-238. doi: 10.1016/j.jad.2023.05.085. Epub 2023 May 29. J Affect Disord. 2023. PMID: 37257779

10

QRFP and GPR103 in the paraventricular nucleus play a role in chronic stress-induced depressive-like symptomatology by enhancing the hypothalamic-pituitary-adrenal axis.

Chen YM, Huang J, Fan H, Li WY, Shi TS, Zhao J, Wang CN, Chen WJ, Zhu BL, Qian JJ, Guan W, Jiang B. Chen YM, et al. Among authors: chen wj. Neuropharmacology. 2025 Jan 1;262:110198. doi: 10.1016/j.neuropharm.2024.110198. Epub 2024 Oct 21. Neuropharmacology. 2025. PMID: 39442911

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