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Peptide-YY3-36/glucagon-like peptide-1 combination treatment of obese diabetic mice improves insulin sensitivity associated with recovered pancreatic β-cell function and synergistic activation of discrete hypothalamic and brainstem neuronal circuitries.
Boland BB, Laker RC, O'Brien S, Sitaula S, Sermadiras I, Nielsen JC, Barkholt P, Roostalu U, Hecksher-Sørensen J, Sejthen SR, Thorbek DD, Suckow A, Burmeister N, Oldham S, Will S, Howard VG, Gill BM, Newton P, Naylor J, Hornigold DC, Austin J, Lantier L, McGuinness OP, Trevaskis JL, Grimsby JS, Rhodes CJ. Boland BB, et al. Among authors: thorbek dd. Mol Metab. 2022 Jan;55:101392. doi: 10.1016/j.molmet.2021.101392. Epub 2021 Nov 12. Mol Metab. 2022. PMID: 34781035 Free PMC article.
Whole-brain activation signatures of weight-lowering drugs.
Hansen HH, Perens J, Roostalu U, Skytte JL, Salinas CG, Barkholt P, Thorbek DD, Rigbolt KTG, Vrang N, Jelsing J, Hecksher-Sørensen J. Hansen HH, et al. Among authors: thorbek dd. Mol Metab. 2021 May;47:101171. doi: 10.1016/j.molmet.2021.101171. Epub 2021 Jan 30. Mol Metab. 2021. PMID: 33529728 Free PMC article.
Quantitative whole-brain 3D imaging of tyrosine hydroxylase-labeled neuron architecture in the mouse MPTP model of Parkinson's disease.
Roostalu U, Salinas CBG, Thorbek DD, Skytte JL, Fabricius K, Barkholt P, John LM, Jurtz VI, Knudsen LB, Jelsing J, Vrang N, Hansen HH, Hecksher-Sørensen J. Roostalu U, et al. Among authors: thorbek dd. Dis Model Mech. 2019 Nov 22;12(11):dmm042200. doi: 10.1242/dmm.042200. Dis Model Mech. 2019. PMID: 31704726 Free PMC article.