Zhao DD - Search Results

1

A novel HSF1 activator ameliorates non-alcoholic steatohepatitis by stimulating mitochondrial adaptive oxidation.

Rao Y, Li C, Hu YT, Xu YH, Song BB, Guo SY, Jiang Z, Zhao DD, Chen SB, Tan JH, Huang SL, Li QJ, Wang XJ, Zhang YJ, Ye JM, Huang ZS. Rao Y, et al. Among authors: zhao dd. Br J Pharmacol. 2022 Apr;179(7):1411-1432. doi: 10.1111/bph.15727. Epub 2022 Feb 9. Br J Pharmacol. 2022. PMID: 34783017 Free article.

2

Gut Akkermansia muciniphila ameliorates metabolic dysfunction-associated fatty liver disease by regulating the metabolism of L-aspartate via gut-liver axis.

Rao Y, Kuang Z, Li C, Guo S, Xu Y, Zhao D, Hu Y, Song B, Jiang Z, Ge Z, Liu X, Li C, Chen S, Ye J, Huang Z, Lu Y. Rao Y, et al. Gut Microbes. 2021 Jan-Dec;13(1):1-19. doi: 10.1080/19490976.2021.1927633. Gut Microbes. 2021. PMID: 34030573 Free PMC article.

3

Palladium oxidative addition complex-enabled synthesis of amino-substituted indolyl-4(3H)-quinazolinones and their antitumor activity evaluation.

Jiang Z, Zhao DD, Hu YT, Rao Y, Guo SY, Xu YH, Li Q, Huang ZS. Jiang Z, et al. Among authors: zhao dd. Org Biomol Chem. 2022 Jan 19;20(3):553-557. doi: 10.1039/d1ob02307a. Org Biomol Chem. 2022. PMID: 34932056

4

Design and Synthesis of Bouchardatine Derivatives as a Novel AMP-Activated Protein Kinase Activator for the Treatment of Colorectal Cancer.

Xu YH, Hu YT, Xu SM, Song BB, Yuan H, Zhao DD, Guo SY, Jiang Z, Wei LY, Rao Y, Tan JH, Huang SL, Li QJ, Chen SB, Huang ZS. Xu YH, et al. Among authors: zhao dd. J Med Chem. 2023 Jun 8;66(11):7387-7404. doi: 10.1021/acs.jmedchem.3c00085. Epub 2023 May 30. J Med Chem. 2023. PMID: 37253101

5

Design, synthesis and evaluation of 2-pyrimidinylindole derivatives as anti-obesity agents by regulating lipid metabolism.

Guo SY, Wei LY, Song BB, Hu YT, Jiang Z, Zhao DD, Xu YH, Lin YW, Xu SM, Chen SB, Huang ZS. Guo SY, et al. Among authors: zhao dd. Eur J Med Chem. 2023 Nov 15;260:115729. doi: 10.1016/j.ejmech.2023.115729. Epub 2023 Aug 19. Eur J Med Chem. 2023. PMID: 37607439

6

Development of Novel N-Acylhydrazone Derivatives with High Anti-obesity Activity and Improved Safety by Exploring the Pharmaceutical Properties of Aldehyde Group.

Jiang Z, Hu YT, Guo SY, Li YX, Zhao DD, Wei LY, Lin YW, Xu SM, Huang SL, Li Q, Tan JH, Rao Y, Chen SB, Huang ZS. Jiang Z, et al. Among authors: zhao dd. J Med Chem. 2024 Jul 25;67(14):12439-12458. doi: 10.1021/acs.jmedchem.4c01242. Epub 2024 Jul 12. J Med Chem. 2024. PMID: 38996004

7

Design, synthesis and structure-activity relationship of novel 2-pyrimidinylindole derivatives as orally available anti-obesity agents.

Wei LY, Lin YW, Luo JC, Li YX, Hu YT, Guo SY, Jiang Z, Zhao DD, Chen SB, Huang ZS. Wei LY, et al. Among authors: zhao dd. Eur J Med Chem. 2024 Nov 5;277:116773. doi: 10.1016/j.ejmech.2024.116773. Epub 2024 Aug 16. Eur J Med Chem. 2024. PMID: 39163779

8

L-aspartate ameliorates diet-induced obesity by increasing adipocyte energy expenditure.

Guo SY, Hu YT, Rao Y, Jiang Z, Li C, Lin YW, Xu SM, Zhao DD, Wei LY, Huang SL, Li QJ, Tan JH, Chen SB, Huang ZS. Guo SY, et al. Among authors: zhao dd. Diabetes Obes Metab. 2025 Feb;27(2):606-618. doi: 10.1111/dom.16053. Epub 2024 Nov 11. Diabetes Obes Metab. 2025. PMID: 39529440

9

Combining idebenone and rosuvastatin prevents atherosclerosis by suppressing oxidative stress and NLRP3 inflammasome activation.

Yu W, Jiang W, Wu W, Wang G, Zhao D, Yan C, Lin P. Yu W, et al. Eur J Pharmacol. 2023 Sep 15;955:175911. doi: 10.1016/j.ejphar.2023.175911. Epub 2023 Jul 13. Eur J Pharmacol. 2023. PMID: 37451421

10

Effects of salinity on growth, physiology, biochemistry and gut microbiota of juvenile grass carp (Ctenopharyngodon idella).

Liu D, Zhang Z, Song Y, Yang J, Lu Y, Lai W, Wu Z, Zhao D, Lin H, Zhang Y, Zhang J, Li S. Liu D, et al. Aquat Toxicol. 2023 May;258:106482. doi: 10.1016/j.aquatox.2023.106482. Epub 2023 Mar 9. Aquat Toxicol. 2023. PMID: 36924593

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