Roybal KT - Search Results

1

Synthetic biology: at the crossroads of genetic engineering and human therapeutics-a Keystone Symposia report.

Cable J, Leonard JN, Lu TK, Xie Z, Chang MW, Fernández LÁ, Lora JM, Kaufman HL, Quintana FJ, Geiger R, F Lesser C, Lynch JP, Hava DL, Cornish VW, Lee GK, DiAndreth B, Fero M, Srivastava R, De Coster T, Roybal KT, Rackham OJL, Kiani S, Zhu I, Hernandez-Lopez RA, Guo T, Chen WCW. Cable J, et al. Among authors: roybal kt. Ann N Y Acad Sci. 2021 Dec;1506(1):98-117. doi: 10.1111/nyas.14710. Epub 2021 Nov 16. Ann N Y Acad Sci. 2021. PMID: 34786712 Review.

2

Synthetic biology approaches to engineer T cells.

Wu CY, Rupp LJ, Roybal KT, Lim WA. Wu CY, et al. Among authors: roybal kt. Curr Opin Immunol. 2015 Aug;35:123-30. doi: 10.1016/j.coi.2015.06.015. Epub 2015 Jul 25. Curr Opin Immunol. 2015. PMID: 26218616 Free PMC article. Review.

3

Refining cell therapy.

Roybal KT. Roybal KT. Science. 2018 Mar 9;359(6380):1112-1113. doi: 10.1126/science.aat0962. Epub 2018 Mar 8. Science. 2018. PMID: 29590036 No abstract available.

4

Precise T cell recognition programs designed by transcriptionally linking multiple receptors.

Williams JZ, Allen GM, Shah D, Sterin IS, Kim KH, Garcia VP, Shavey GE, Yu W, Puig-Saus C, Tsoi J, Ribas A, Roybal KT, Lim WA. Williams JZ, et al. Among authors: roybal kt. Science. 2020 Nov 27;370(6520):1099-1104. doi: 10.1126/science.abc6270. Science. 2020. PMID: 33243890 Free PMC article.

5

DNA scaffolds enable efficient and tunable functionalization of biomaterials for immune cell modulation.

Huang X, Williams JZ, Chang R, Li Z, Burnett CE, Hernandez-Lopez R, Setiady I, Gai E, Patterson DM, Yu W, Roybal KT, Lim WA, Desai TA. Huang X, et al. Among authors: roybal kt. Nat Nanotechnol. 2021 Feb;16(2):214-223. doi: 10.1038/s41565-020-00813-z. Epub 2020 Dec 14. Nat Nanotechnol. 2021. PMID: 33318641 Free PMC article.

6

Modular design of synthetic receptors for programmed gene regulation in cell therapies.

Zhu I, Liu R, Garcia JM, Hyrenius-Wittsten A, Piraner DI, Alavi J, Israni DV, Liu B, Khalil AS, Roybal KT. Zhu I, et al. Among authors: roybal kt. Cell. 2022 Apr 14;185(8):1431-1443.e16. doi: 10.1016/j.cell.2022.03.023. Cell. 2022. PMID: 35427499 Free PMC article.

7

Antigen-Dependent Inducible T-Cell Reporter System for PET Imaging of Breast Cancer and Glioblastoma.

Shin J, Parker MFL, Zhu I, Alanizi A, Rodriguez CI, Liu R, Watchmaker PB, Kalita M, Blecha J, Luu J, Wright B, Lapi SE, Flavell RR, Okada H, Tlsty TD, Roybal KT, Wilson DM. Shin J, et al. Among authors: roybal kt. J Nucl Med. 2023 Jan;64(1):137-144. doi: 10.2967/jnumed.122.264284. Epub 2022 Aug 18. J Nucl Med. 2023. PMID: 35981900 Free PMC article.

8

Multidimensional control of therapeutic human cell function with synthetic gene circuits.

Li HS, Israni DV, Gagnon KA, Gan KA, Raymond MH, Sander JD, Roybal KT, Joung JK, Wong WW, Khalil AS. Li HS, et al. Among authors: roybal kt. Science. 2022 Dec 16;378(6625):1227-1234. doi: 10.1126/science.ade0156. Epub 2022 Dec 15. Science. 2022. PMID: 36520914 Free PMC article.

9

Synthesizing a Smarter CAR T Cell: Advanced Engineering of T-cell Immunotherapies.

Zhu I, Piraner DI, Roybal KT. Zhu I, et al. Among authors: roybal kt. Cancer Immunol Res. 2023 Aug 3;11(8):1030-1043. doi: 10.1158/2326-6066.CIR-22-0962. Cancer Immunol Res. 2023. PMID: 37429007 Free PMC article.

10

Naturally occurring T cell mutations enhance engineered T cell therapies.

Garcia J, Daniels J, Lee Y, Zhu I, Cheng K, Liu Q, Goodman D, Burnett C, Law C, Thienpont C, Alavi J, Azimi C, Montgomery G, Roybal KT, Choi J. Garcia J, et al. Among authors: roybal kt. Nature. 2024 Feb;626(7999):626-634. doi: 10.1038/s41586-024-07018-7. Epub 2024 Feb 7. Nature. 2024. PMID: 38326614

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