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mTOR activation in CD8+ cells contributes to disease activity of rheumatoid arthritis and increases therapeutic response to TNF inhibitors.
Zhang M, Iwata S, Sonomoto K, Ueno M, Fujita Y, Anan J, Miyazaki Y, Ohkubo N, Sumikawa MH, Todoroki Y, Miyata H, Nagayasu A, Kanda R, Hao H, Trimova G, Lee S, Nakayamada S, Sakata K, Tanaka Y. Zhang M, et al. Among authors: sakata k. Rheumatology (Oxford). 2022 Jul 6;61(7):3010-3022. doi: 10.1093/rheumatology/keab834. Rheumatology (Oxford). 2022. PMID: 34791054
Tofacitinib, a JAK inhibitor, inhibits human B cell activation in vitro.
Wang SP, Iwata S, Nakayamada S, Sakata K, Yamaoka K, Tanaka Y. Wang SP, et al. Among authors: sakata k. Ann Rheum Dis. 2014 Dec;73(12):2213-5. doi: 10.1136/annrheumdis-2014-205615. Epub 2014 Aug 25. Ann Rheum Dis. 2014. PMID: 25157177 No abstract available.
Histamine inhibits differentiation of skin fibroblasts into myofibroblasts.
Lin L, Yamagata K, Nakayamada S, Sawamukai N, Yamaoka K, Sakata K, Nakano K, Tanaka Y. Lin L, et al. Among authors: sakata k. Biochem Biophys Res Commun. 2015 Jul 31;463(3):434-9. doi: 10.1016/j.bbrc.2015.05.094. Epub 2015 May 31. Biochem Biophys Res Commun. 2015. PMID: 26036574
1,992 results