Holvey-Bates EG - Search Results

1

The ubiquitin E3 ligase FBXO22 degrades PD-L1 and sensitizes cancer cells to DNA damage.

De S, Holvey-Bates EG, Mahen K, Willard B, Stark GR. De S, et al. Among authors: holvey bates eg. Proc Natl Acad Sci U S A. 2021 Nov 23;118(47):e2112674118. doi: 10.1073/pnas.2112674118. Proc Natl Acad Sci U S A. 2021. PMID: 34795058 Free PMC article.

2

IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage.

Cheon H, Holvey-Bates EG, Schoggins JW, Forster S, Hertzog P, Imanaka N, Rice CM, Jackson MW, Junk DJ, Stark GR. Cheon H, et al. Among authors: holvey bates eg. EMBO J. 2013 Oct 16;32(20):2751-63. doi: 10.1038/emboj.2013.203. Epub 2013 Sep 24. EMBO J. 2013. PMID: 24065129 Free PMC article.

3

Cell crowding induces interferon regulatory factor 9, which confers resistance to chemotherapeutic drugs.

Kolosenko I, Fryknäs M, Forsberg S, Johnsson P, Cheon H, Holvey-Bates EG, Edsbäcker E, Pellegrini P, Rassoolzadeh H, Brnjic S, Larsson R, Stark GR, Grandér D, Linder S, Tamm KP, De Milito A. Kolosenko I, et al. Among authors: holvey bates eg. Int J Cancer. 2015 Feb 15;136(4):E51-61. doi: 10.1002/ijc.29161. Epub 2014 Sep 4. Int J Cancer. 2015. PMID: 25156627

4

OAS-RNase L innate immune pathway mediates the cytotoxicity of a DNA-demethylating drug.

Banerjee S, Gusho E, Gaughan C, Dong B, Gu X, Holvey-Bates E, Talukdar M, Li Y, Weiss SR, Sicheri F, Saunthararajah Y, Stark GR, Silverman RH. Banerjee S, et al. Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):5071-5076. doi: 10.1073/pnas.1815071116. Epub 2019 Feb 27. Proc Natl Acad Sci U S A. 2019. PMID: 30814222 Free PMC article.

5

Suppressing PARylation by 2',5'-oligoadenylate synthetase 1 inhibits DNA damage-induced cell death.

Kondratova AA, Cheon H, Dong B, Holvey-Bates EG, Hasipek M, Taran I, Gaughan C, Jha BK, Silverman RH, Stark GR. Kondratova AA, et al. Among authors: holvey bates eg. EMBO J. 2020 Jun 2;39(11):e101573. doi: 10.15252/embj.2019101573. Epub 2020 Apr 23. EMBO J. 2020. PMID: 32323871 Free PMC article.

6

A virus-induced conformational switch of STAT1-STAT2 dimers boosts antiviral defenses.

Wang Y, Song Q, Huang W, Lin Y, Wang X, Wang C, Willard B, Zhao C, Nan J, Holvey-Bates E, Wang Z, Taylor D, Yang J, Stark GR. Wang Y, et al. Cell Res. 2021 Feb;31(2):206-218. doi: 10.1038/s41422-020-0386-6. Epub 2020 Aug 5. Cell Res. 2021. PMID: 32759968 Free PMC article.

7

Suppressing PARylation by 2',5'-oligoadenylate synthetase 1 inhibits DNA damage-induced cell death.

Kondratova A, Cheon H, Dong B, Holvey-Bates EG, Hasipek M, Taran I, Gaughan C, Jha BK, Silverman RH, Stark GR. Kondratova A, et al. Among authors: holvey bates eg. EMBO J. 2020 Oct 15;39(20):e106593. doi: 10.15252/embj.2020106593. EMBO J. 2020. PMID: 33058249 Free PMC article.

8

PD-L1 sustains chronic, cancer cell-intrinsic responses to type I interferon, enhancing resistance to DNA damage.

Cheon H, Holvey-Bates EG, McGrail DJ, Stark GR. Cheon H, et al. Among authors: holvey bates eg. Proc Natl Acad Sci U S A. 2021 Nov 23;118(47):e2112258118. doi: 10.1073/pnas.2112258118. Proc Natl Acad Sci U S A. 2021. PMID: 34799452 Free PMC article.

9

STAT2 hinders STING intracellular trafficking and reshapes its activation in response to DNA damage.

Wang C, Nan J, Holvey-Bates E, Chen X, Wightman S, Latif MB, Zhao J, Li X, Sen GC, Stark GR, Wang Y. Wang C, et al. Proc Natl Acad Sci U S A. 2023 Apr 18;120(16):e2216953120. doi: 10.1073/pnas.2216953120. Epub 2023 Apr 10. Proc Natl Acad Sci U S A. 2023. PMID: 37036972 Free PMC article.

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