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Page 1
Individualized VDJ recombination predisposes the available Ig sequence space.
Slabodkin A, Chernigovskaya M, Mikocziova I, Akbar R, Scheffer L, Pavlović M, Bashour H, Snapkov I, Mehta BB, Weber CR, Gutierrez-Marcos J, Sollid LM, Haff IH, Sandve GK, Robert PA, Greiff V. Slabodkin A, et al. Among authors: haff ih. Genome Res. 2021 Dec;31(12):2209-2224. doi: 10.1101/gr.275373.121. Epub 2021 Nov 23. Genome Res. 2021. PMID: 34815307 Free PMC article.
The immuneML ecosystem for machine learning analysis of adaptive immune receptor repertoires.
Pavlović M, Scheffer L, Motwani K, Kanduri C, Kompova R, Vazov N, Waagan K, Bernal FLM, Costa AA, Corrie B, Akbar R, Al Hajj GS, Balaban G, Brusko TM, Chernigovskaya M, Christley S, Cowell LG, Frank R, Grytten I, Gundersen S, Haff IH, Hovig E, Hsieh PH, Klambauer G, Kuijjer ML, Lund-Andersen C, Martini A, Minotto T, Pensar J, Rand K, Riccardi E, Robert PA, Rocha A, Slabodkin A, Snapkov I, Sollid LM, Titov D, Weber CR, Widrich M, Yaari G, Greiff V, Sandve GK. Pavlović M, et al. Among authors: haff ih. Nat Mach Intell. 2021 Nov;3(11):936-944. doi: 10.1038/s42256-021-00413-z. Epub 2021 Nov 16. Nat Mach Intell. 2021. PMID: 37396030 Free PMC article.
Predictability of antigen binding based on short motifs in the antibody CDRH3.
Scheffer L, Reber EE, Mehta BB, Pavlović M, Chernigovskaya M, Richardson E, Akbar R, Lund-Johansen F, Greiff V, Haff IH, Sandve GK. Scheffer L, et al. Among authors: haff ih. Brief Bioinform. 2024 Sep 23;25(6):bbae537. doi: 10.1093/bib/bbae537. Brief Bioinform. 2024. PMID: 39438077 Free PMC article.
Unconstrained generation of synthetic antibody-antigen structures to guide machine learning methodology for antibody specificity prediction.
Robert PA, Akbar R, Frank R, Pavlović M, Widrich M, Snapkov I, Slabodkin A, Chernigovskaya M, Scheffer L, Smorodina E, Rawat P, Mehta BB, Vu MH, Mathisen IF, Prósz A, Abram K, Olar A, Miho E, Haug DTT, Lund-Johansen F, Hochreiter S, Haff IH, Klambauer G, Sandve GK, Greiff V. Robert PA, et al. Among authors: haff ih. Nat Comput Sci. 2022 Dec;2(12):845-865. doi: 10.1038/s43588-022-00372-4. Epub 2022 Dec 19. Nat Comput Sci. 2022. PMID: 38177393