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Acquired Resistance to Antiangiogenic Therapies in Hepatocellular Carcinoma Is Mediated by Yes-Associated Protein 1 Activation and Transient Expansion of Stem-Like Cancer Cells.
Castven D, Czauderna C, Becker D, Pereira S, Schmitt J, Weinmann A, Shah V, Hajduk J, Keggenhoff F, Binder H, Keck T, Heilmann-Heimbach S, Wörns MA, Thorgeirsson SS, Breuhahn K, Galle PR, Marquardt JU. Castven D, et al. Among authors: binder h. Hepatol Commun. 2022 May;6(5):1140-1156. doi: 10.1002/hep4.1869. Epub 2021 Nov 24. Hepatol Commun. 2022. PMID: 34817932 Free PMC article.
Translating bioinformatics in oncology: guilt-by-profiling analysis and identification of KIF18B and CDCA3 as novel driver genes in carcinogenesis.
Itzel T, Scholz P, Maass T, Krupp M, Marquardt JU, Strand S, Becker D, Staib F, Binder H, Roessler S, Wang XW, Thorgeirsson S, Müller M, Galle PR, Teufel A. Itzel T, et al. Among authors: binder h. Bioinformatics. 2015 Jan 15;31(2):216-24. doi: 10.1093/bioinformatics/btu586. Epub 2014 Sep 18. Bioinformatics. 2015. PMID: 25236463 Free PMC article.
Epigenetic modifications precede molecular alterations and drive human hepatocarcinogenesis.
Czauderna C, Poplawski A, O'Rourke CJ, Castven D, Pérez-Aguilar B, Becker D, Heilmann-Heimbach S, Odenthal M, Amer W, Schmiel M, Drebber U, Binder H, Ridder DA, Schindeldecker M, Straub BK, Galle PR, Andersen JB, Thorgeirsson SS, Park YN, Marquardt JU. Czauderna C, et al. Among authors: binder h. JCI Insight. 2021 Sep 8;6(17):e146196. doi: 10.1172/jci.insight.146196. JCI Insight. 2021. PMID: 34375307 Free PMC article.
T-cell exhaustion and residency dynamics inform clinical outcomes in hepatocellular carcinoma.
Barsch M, Salié H, Schlaak AE, Zhang Z, Hess M, Mayer LS, Tauber C, Otto-Mora P, Ohtani T, Nilsson T, Wischer L, Winkler F, Manne S, Rech A, Schmitt-Graeff A, Bronsert P, Hofmann M, Neumann-Haefelin C, Boettler T, Fichtner-Feigl S, van Boemmel F, Berg T, Rimassa L, Di Tommaso L, Saeed A, D'Alessio A, Pinato DJ, Bettinger D, Binder H, John Wherry E, Schultheiss M, Thimme R, Bengsch B. Barsch M, et al. Among authors: binder h. J Hepatol. 2022 Aug;77(2):397-409. doi: 10.1016/j.jhep.2022.02.032. Epub 2022 Apr 1. J Hepatol. 2022. PMID: 35367533
Structured Early detection of Asymptomatic Liver Cirrhosis: Results of the population-based liver screening program SEAL.
Labenz C, Arslanow A, Nguyen-Tat M, Nagel M, Wörns MA, Reichert MC, Heil FJ, Mainz D, Zimper G, Römer B, Binder H, Farin-Glattacker E, Fichtner U, Graf E, Stelzer D, Van Ewijk R, Ortner J, Velthuis L, Lammert F, Galle PR. Labenz C, et al. Among authors: binder h. J Hepatol. 2022 Sep;77(3):695-701. doi: 10.1016/j.jhep.2022.04.009. Epub 2022 Apr 23. J Hepatol. 2022. PMID: 35472313
961 results