Laufer S - Search Results

1

High-Throughput Screening Platform in Postnatal Heart Cells and Chemical Probe Toolbox to Assess Cardiomyocyte Proliferation.

Carrillo García C, Becker C, Forster M, Lohmann S, Freitag P, Laufer S, Sievers S, Fleischmann BK, Hesse M, Schade D. Carrillo García C, et al. Among authors: laufer s. J Med Chem. 2022 Jan 27;65(2):1505-1524. doi: 10.1021/acs.jmedchem.1c01173. Epub 2021 Nov 24. J Med Chem. 2022. PMID: 34818008

2

From imidazoles to pyrimidines: new inhibitors of cytokine release.

Laufer SA, Wagner GK. Laufer SA, et al. J Med Chem. 2002 Jun 20;45(13):2733-40. doi: 10.1021/jm011098a. J Med Chem. 2002. PMID: 12061876

3

Imidazole inhibitors of cytokine release: probing substituents in the 2 position.

Laufer SA, Striegel HG, Wagner GK. Laufer SA, et al. J Med Chem. 2002 Oct 10;45(21):4695-705. doi: 10.1021/jm020873z. J Med Chem. 2002. PMID: 12361396

4

Tetrasubstituted imidazole inhibitors of cytokine release: probing substituents in the N-1 position.

Laufer SA, Zimmermann W, Ruff KJ. Laufer SA, et al. J Med Chem. 2004 Dec 2;47(25):6311-25. doi: 10.1021/jm0496584. J Med Chem. 2004. PMID: 15566301

5

Synthesis and biological testing of purine derivatives as potential ATP-competitive kinase inhibitors.

Laufer SA, Domeyer DM, Scior TR, Albrecht W, Hauser DR. Laufer SA, et al. J Med Chem. 2005 Feb 10;48(3):710-22. doi: 10.1021/jm0408767. J Med Chem. 2005. PMID: 15689155

6

New approaches to the treatment of inflammatory disorders small molecule inhibitors of p38 MAP kinase.

Peifer C, Wagner G, Laufer S. Peifer C, et al. Among authors: laufer s. Curr Top Med Chem. 2006;6(2):113-49. doi: 10.2174/156802606775270323. Curr Top Med Chem. 2006. PMID: 16454763 Review.

7

Design, synthesis, and biological evaluation of phenylamino-substituted 6,11-dihydro-dibenzo[b,e]oxepin-11-ones and dibenzo[a,d]cycloheptan-5-ones: novel p38 MAP kinase inhibitors.

Laufer SA, Ahrens GM, Karcher SC, Hering JS, Niess R. Laufer SA, et al. J Med Chem. 2006 Dec 28;49(26):7912-5. doi: 10.1021/jm061072p. J Med Chem. 2006. PMID: 17181176

8

From five- to six-membered rings: 3,4-diarylquinolinone as lead for novel p38MAP kinase inhibitors.

Peifer C, Kinkel K, Abadleh M, Schollmeyer D, Laufer S. Peifer C, et al. Among authors: laufer s. J Med Chem. 2007 Mar 22;50(6):1213-21. doi: 10.1021/jm061097o. Epub 2007 Feb 27. J Med Chem. 2007. PMID: 17323937

9

Synthesis, biological testing, and binding mode prediction of 6,9-diarylpurin-8-ones as p38 MAP kinase inhibitors.

Hauser DR, Scior T, Domeyer DM, Kammerer B, Laufer SA. Hauser DR, et al. J Med Chem. 2007 May 3;50(9):2060-6. doi: 10.1021/jm061061w. Epub 2007 Apr 6. J Med Chem. 2007. PMID: 17411025

10

Implications for selectivity of 3,4-diarylquinolinones as p38alphaMAP kinase inhibitors.

Peifer C, Urich R, Schattel V, Abadleh M, Röttig M, Kohlbacher O, Laufer S. Peifer C, et al. Among authors: laufer s. Bioorg Med Chem Lett. 2008 Feb 15;18(4):1431-5. doi: 10.1016/j.bmcl.2007.12.073. Epub 2008 Jan 5. Bioorg Med Chem Lett. 2008. PMID: 18207396

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