Meiler J - Search Results

1

Binding of Natural Peptide Ligands to the Neuropeptide Y₅ Receptor.

Rudolf S, Kaempf K, Vu O, Meiler J, Beck-Sickinger AG, Coin I. Rudolf S, et al. Among authors: meiler j. Angew Chem Int Ed Engl. 2022 Jan 26;61(5):e202108738. doi: 10.1002/anie.202108738. Epub 2021 Dec 16. Angew Chem Int Ed Engl. 2022. PMID: 34822209 Free PMC article.

2

Selective mode of action of guanidine-containing non-peptides at human NPFF receptors.

Findeisen M, Würker C, Rathmann D, Meier R, Meiler J, Olsson R, Beck-Sickinger AG. Findeisen M, et al. Among authors: meiler j. J Med Chem. 2012 Jul 12;55(13):6124-36. doi: 10.1021/jm300535s. Epub 2012 Jun 26. J Med Chem. 2012. PMID: 22708927 Free PMC article.

3

Ligand-mimicking receptor variant discloses binding and activation mode of prolactin-releasing peptide.

Rathmann D, Lindner D, DeLuca SH, Kaufmann KW, Meiler J, Beck-Sickinger AG. Rathmann D, et al. Among authors: meiler j. J Biol Chem. 2012 Sep 14;287(38):32181-94. doi: 10.1074/jbc.M112.349852. Epub 2012 Jul 9. J Biol Chem. 2012. PMID: 22778259 Free PMC article.

4

The activity of prolactin releasing peptide correlates with its helicity.

Deluca SH, Rathmann D, Beck-Sickinger AG, Meiler J. Deluca SH, et al. Among authors: meiler j. Biopolymers. 2013 May;99(5):314-25. doi: 10.1002/bip.22162. Biopolymers. 2013. PMID: 23426574 Free PMC article.

5

Pancreatic polypeptide is recognized by two hydrophobic domains of the human Y4 receptor binding pocket.

Pedragosa-Badia X, Sliwoski GR, Dong Nguyen E, Lindner D, Stichel J, Kaufmann KW, Meiler J, Beck-Sickinger AG. Pedragosa-Badia X, et al. Among authors: meiler j. J Biol Chem. 2014 Feb 28;289(9):5846-59. doi: 10.1074/jbc.M113.502021. Epub 2013 Dec 27. J Biol Chem. 2014. PMID: 24375409 Free PMC article.

6

Position and length of fatty acids strongly affect receptor selectivity pattern of human pancreatic polypeptide analogues.

Mäde V, Bellmann-Sickert K, Kaiser A, Meiler J, Beck-Sickinger AG. Mäde V, et al. Among authors: meiler j. ChemMedChem. 2014 Nov;9(11):2463-74. doi: 10.1002/cmdc.201402235. Epub 2014 Aug 22. ChemMedChem. 2014. PMID: 25156249 Free PMC article.

7

Integrating solid-state NMR and computational modeling to investigate the structure and dynamics of membrane-associated ghrelin.

Vortmeier G, DeLuca SH, Els-Heindl S, Chollet C, Scheidt HA, Beck-Sickinger AG, Meiler J, Huster D. Vortmeier G, et al. Among authors: meiler j. PLoS One. 2015 Mar 24;10(3):e0122444. doi: 10.1371/journal.pone.0122444. eCollection 2015. PLoS One. 2015. PMID: 25803439 Free PMC article.

8

Unwinding of the C-Terminal Residues of Neuropeptide Y is critical for Y₂ Receptor Binding and Activation.

Kaiser A, Müller P, Zellmann T, Scheidt HA, Thomas L, Bosse M, Meier R, Meiler J, Huster D, Beck-Sickinger AG, Schmidt P. Kaiser A, et al. Among authors: meiler j. Angew Chem Int Ed Engl. 2015 Jun 15;54(25):7446-9. doi: 10.1002/anie.201411688. Epub 2015 Apr 29. Angew Chem Int Ed Engl. 2015. PMID: 25924821 Free PMC article.

9

Discovery of Small-Molecule Modulators of the Human Y4 Receptor.

Sliwoski G, Schubert M, Stichel J, Weaver D, Beck-Sickinger AG, Meiler J. Sliwoski G, et al. Among authors: meiler j. PLoS One. 2016 Jun 13;11(6):e0157146. doi: 10.1371/journal.pone.0157146. eCollection 2016. PLoS One. 2016. PMID: 27294784 Free PMC article.

10

A Deep Hydrophobic Binding Cavity is the Main Interaction for Different Y₂ R Antagonists.

Burkert K, Zellmann T, Meier R, Kaiser A, Stichel J, Meiler J, Mittapalli GK, Roberts E, Beck-Sickinger AG. Burkert K, et al. Among authors: meiler j. ChemMedChem. 2017 Jan 5;12(1):75-85. doi: 10.1002/cmdc.201600433. Epub 2016 Nov 30. ChemMedChem. 2017. PMID: 27874262

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