Roh EJ - Search Results

1

AKF-D52, a Synthetic Phenoxypyrimidine-Urea Derivative, Triggers Extrinsic/Intrinsic Apoptosis and Cytoprotective Autophagy in Human Non-Small Cell Lung Cancer Cells.

Gil HS, Lee JH, Farag AK, Hassan AHE, Chung KS, Choi JH, Roh EJ, Lee KT. Gil HS, et al. Among authors: roh ej. Cancers (Basel). 2021 Nov 22;13(22):5849. doi: 10.3390/cancers13225849. Cancers (Basel). 2021. PMID: 34831003 Free PMC article.

2

Targeting EGFR/HER2 tyrosine kinases with a new potent series of 6-substituted 4-anilinoquinazoline hybrids: Design, synthesis, kinase assay, cell-based assay, and molecular docking.

Elkamhawy A, Farag AK, Viswanath AN, Bedair TM, Leem DG, Lee KT, Pae AN, Roh EJ. Elkamhawy A, et al. Among authors: roh ej. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5147-54. doi: 10.1016/j.bmcl.2015.10.003. Epub 2015 Oct 9. Bioorg Med Chem Lett. 2015. PMID: 26475520

3

Discovery of 1-(3-(benzyloxy)pyridin-2-yl)-3-(2-(piperazin-1-yl)ethyl)urea: A new modulator for amyloid beta-induced mitochondrial dysfunction.

Elkamhawy A, Park JE, Hassan AHE, Ra H, Pae AN, Lee J, Park BG, Moon B, Park HM, Roh EJ. Elkamhawy A, et al. Among authors: roh ej. Eur J Med Chem. 2017 Mar 10;128:56-69. doi: 10.1016/j.ejmech.2016.12.057. Epub 2016 Dec 29. Eur J Med Chem. 2017. PMID: 28152427

4

Design, synthesis, biological evaluation and molecular modelling of 2-(2-aryloxyphenyl)-1,4-dihydroisoquinolin-3(2H)-ones: A novel class of TSPO ligands modulating amyloid-β-induced mPTP opening.

Elkamhawy A, Park JE, Hassan AHE, Pae AN, Lee J, Park BG, Paik S, Do J, Park JH, Park KD, Moon B, Park WK, Cho H, Jeong DY, Roh EJ. Elkamhawy A, et al. Among authors: roh ej. Eur J Pharm Sci. 2017 Jun 15;104:366-381. doi: 10.1016/j.ejps.2017.04.015. Epub 2017 Apr 21. Eur J Pharm Sci. 2017. PMID: 28435076

5

Synthesis and evaluation of new pyridyl/pyrazinyl thiourea derivatives: Neuroprotection against amyloid-β-induced toxicity.

Park JE, Elkamhawy A, Hassan AHE, Pae AN, Lee J, Paik S, Park BG, Roh EJ. Park JE, et al. Among authors: roh ej. Eur J Med Chem. 2017 Dec 1;141:322-334. doi: 10.1016/j.ejmech.2017.09.043. Epub 2017 Sep 22. Eur J Med Chem. 2017. PMID: 29031076

6

Hit discovery of 4-amino-N-(4-(3-(trifluoromethyl)phenoxy)pyrimidin-5-yl)benzamide: A novel EGFR inhibitor from a designed small library.

Elkamhawy A, Paik S, Hassan AHE, Lee YS, Roh EJ. Elkamhawy A, et al. Among authors: roh ej. Bioorg Chem. 2017 Dec;75:393-405. doi: 10.1016/j.bioorg.2017.10.009. Epub 2017 Nov 5. Bioorg Chem. 2017. PMID: 29102722

7

Novel LCK/FMS inhibitors based on phenoxypyrimidine scaffold as potential treatment for inflammatory disorders.

Farag AK, Elkamhawy A, Londhe AM, Lee KT, Pae AN, Roh EJ. Farag AK, et al. Among authors: roh ej. Eur J Med Chem. 2017 Dec 1;141:657-675. doi: 10.1016/j.ejmech.2017.10.003. Epub 2017 Oct 4. Eur J Med Chem. 2017. PMID: 29107425

8

Synthesis and evaluation of 2-(3-arylureido)pyridines and 2-(3-arylureido)pyrazines as potential modulators of Aβ-induced mitochondrial dysfunction in Alzheimer's disease.

Elkamhawy A, Park JE, Hassan AHE, Pae AN, Lee J, Park BG, Roh EJ. Elkamhawy A, et al. Among authors: roh ej. Eur J Med Chem. 2018 Jan 20;144:529-543. doi: 10.1016/j.ejmech.2017.12.045. Epub 2017 Dec 14. Eur J Med Chem. 2018. PMID: 29288949

9

Repositioning of the antipsychotic trifluoperazine: Synthesis, biological evaluation and in silico study of trifluoperazine analogs as anti-glioblastoma agents.

Kang S, Lee JM, Jeon B, Elkamhawy A, Paik S, Hong J, Oh SJ, Paek SH, Lee CJ, Hassan AHE, Kang SS, Roh EJ. Kang S, et al. Among authors: roh ej. Eur J Med Chem. 2018 May 10;151:186-198. doi: 10.1016/j.ejmech.2018.03.055. Epub 2018 Mar 23. Eur J Med Chem. 2018. PMID: 29614416

10

Death-associated protein kinase (DAPK) family modulators: Current and future therapeutic outcomes.

Farag AK, Roh EJ. Farag AK, et al. Among authors: roh ej. Med Res Rev. 2019 Jan;39(1):349-385. doi: 10.1002/med.21518. Epub 2018 Jun 27. Med Res Rev. 2019. PMID: 29949198 Review.

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