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Substrate specificity studies of the cysteine peptidases falcipain-2 and falcipain-3 from Plasmodium falciparum and demonstration of their kininogenase activity.
Cotrin SS, Gouvêa IE, Melo PM, Bagnaresi P, Assis DM, Araújo MS, Juliano MA, Gazarini ML, Rosenthal PJ, Juliano L, Carmona AK. Cotrin SS, et al. Among authors: gazarini ml. Mol Biochem Parasitol. 2013 Feb;187(2):111-6. doi: 10.1016/j.molbiopara.2013.01.002. Epub 2013 Jan 24. Mol Biochem Parasitol. 2013. PMID: 23354130
Specific calpain activity evaluation in Plasmodium parasites.
Gomes MM, Budu A, Ventura PD, Bagnaresi P, Cotrin SS, Cunha RL, Carmona AK, Juliano L, Gazarini ML. Gomes MM, et al. Among authors: gazarini ml. Anal Biochem. 2015 Jan 1;468:22-7. doi: 10.1016/j.ab.2014.09.005. Epub 2014 Oct 2. Anal Biochem. 2015. PMID: 25281458
Calmidazolium evokes high calcium fluctuations in Plasmodium falciparum.
Budu A, Gomes MM, Melo PM, El Chamy Maluf S, Bagnaresi P, Azevedo MF, Carmona AK, Gazarini ML. Budu A, et al. Among authors: gazarini ml. Cell Signal. 2016 Mar;28(3):125-135. doi: 10.1016/j.cellsig.2015.12.003. Epub 2015 Dec 10. Cell Signal. 2016. PMID: 26689736
KBE009: An antimalarial bestatin-like inhibitor of the Plasmodium falciparum M1 aminopeptidase discovered in an Ugi multicomponent reaction-derived peptidomimetic library.
González-Bacerio J, Maluf SEC, Méndez Y, Pascual I, Florent I, Melo PMS, Budu A, Ferreira JC, Moreno E, Carmona AK, Rivera DG, Alonso Del Rivero M, Gazarini ML. González-Bacerio J, et al. Among authors: gazarini ml. Bioorg Med Chem. 2017 Sep 1;25(17):4628-4636. doi: 10.1016/j.bmc.2017.06.047. Epub 2017 Jul 4. Bioorg Med Chem. 2017. PMID: 28728898
42 results