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KBE009: An antimalarial bestatin-like inhibitor of the Plasmodium falciparum M1 aminopeptidase discovered in an Ugi multicomponent reaction-derived peptidomimetic library.
González-Bacerio J, Maluf SEC, Méndez Y, Pascual I, Florent I, Melo PMS, Budu A, Ferreira JC, Moreno E, Carmona AK, Rivera DG, Alonso Del Rivero M, Gazarini ML. González-Bacerio J, et al. Bioorg Med Chem. 2017 Sep 1;25(17):4628-4636. doi: 10.1016/j.bmc.2017.06.047. Epub 2017 Jul 4. Bioorg Med Chem. 2017. PMID: 28728898
Discovery of potent and selective inhibitors of the Escherichia coli M1-aminopeptidase via multicomponent solid-phase synthesis of tetrazole-peptidomimetics.
Méndez Y, De Armas G, Pérez I, Rojas T, Valdés-Tresanco ME, Izquierdo M, Alonso Del Rivero M, Álvarez-Ginarte YM, Valiente PA, Soto C, de León L, Vasco AV, Scott WL, Westermann B, González-Bacerio J, Rivera DG. Méndez Y, et al. Eur J Med Chem. 2019 Feb 1;163:481-499. doi: 10.1016/j.ejmech.2018.11.074. Epub 2018 Dec 1. Eur J Med Chem. 2019. PMID: 30544037 Free article.
Parasite Metalo-aminopeptidases as Targets in Human Infectious Diseases.
Aguado ME, Izquierdo M, González-Matos M, Varela AC, Méndez Y, Del Rivero MA, Rivera DG, González-Bacerio J. Aguado ME, et al. Among authors: gonzalez bacerio j. Curr Drug Targets. 2023;24(5):416-461. doi: 10.2174/1389450124666230224140724. Curr Drug Targets. 2023. PMID: 36825701 Review.
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