Schilter H - Search Results

1

An activity-based bioprobe differentiates a novel small molecule inhibitor from a LOXL2 antibody and provides renewed promise for anti-fibrotic therapeutic strategies.

Findlay A, Turner C, Schilter H, Deodhar M, Zhou W, Perryman L, Foot J, Zahoor A, Yao Y, Hamilton R, Brock M, Raso C, Stolp J, Galati M, Hamprecht D, Charlton B, Jarolimek W. Findlay A, et al. Among authors: schilter h. Clin Transl Med. 2021 Nov;11(11):e572. doi: 10.1002/ctm2.572. Clin Transl Med. 2021. PMID: 34841699 Free PMC article. No abstract available.

2

PXS-4681A, a potent and selective mechanism-based inhibitor of SSAO/VAP-1 with anti-inflammatory effects in vivo.

Foot JS, Yow TT, Schilter H, Buson A, Deodhar M, Findlay AD, Guo L, McDonald IA, Turner CI, Zhou W, Jarolimek W. Foot JS, et al. Among authors: schilter h. J Pharmacol Exp Ther. 2013 Nov;347(2):365-74. doi: 10.1124/jpet.113.207613. Epub 2013 Aug 13. J Pharmacol Exp Ther. 2013. PMID: 23943052

3

The lysyl oxidase like 2/3 enzymatic inhibitor, PXS-5153A, reduces crosslinks and ameliorates fibrosis.

Schilter H, Findlay AD, Perryman L, Yow TT, Moses J, Zahoor A, Turner CI, Deodhar M, Foot JS, Zhou W, Greco A, Joshi A, Rayner B, Townsend S, Buson A, Jarolimek W. Schilter H, et al. J Cell Mol Med. 2019 Mar;23(3):1759-1770. doi: 10.1111/jcmm.14074. Epub 2018 Dec 9. J Cell Mol Med. 2019. PMID: 30536539 Free PMC article.

4

Identification and Optimization of Mechanism-Based Fluoroallylamine Inhibitors of Lysyl Oxidase-like 2/3.

Findlay AD, Foot JS, Buson A, Deodhar M, Jarnicki AG, Hansbro PM, Liu G, Schilter H, Turner CI, Zhou W, Jarolimek W. Findlay AD, et al. Among authors: schilter h. J Med Chem. 2019 Nov 14;62(21):9874-9889. doi: 10.1021/acs.jmedchem.9b01283. Epub 2019 Oct 16. J Med Chem. 2019. PMID: 31580073

5

Effects of an anti-inflammatory VAP-1/SSAO inhibitor, PXS-4728A, on pulmonary neutrophil migration.

Schilter HC, Collison A, Russo RC, Foot JS, Yow TT, Vieira AT, Tavares LD, Mattes J, Teixeira MM, Jarolimek W. Schilter HC, et al. Respir Res. 2015 Mar 20;16(1):42. doi: 10.1186/s12931-015-0200-z. Respir Res. 2015. PMID: 25889951 Free PMC article.

6

Semicarbazide-sensitive amine oxidase (SSAO) inhibition ameliorates kidney fibrosis in a unilateral ureteral obstruction murine model.

Wong M, Saad S, Zhang J, Gross S, Jarolimek W, Schilter H, Chen JA, Gill AJ, Pollock CA, Wong MG. Wong M, et al. Among authors: schilter h. Am J Physiol Renal Physiol. 2014 Oct 15;307(8):F908-16. doi: 10.1152/ajprenal.00698.2013. Epub 2014 Aug 20. Am J Physiol Renal Physiol. 2014. PMID: 25143459 Free article.

7

The mannose-6-phosphate analogue, PXS64, inhibits fibrosis via TGF-β1 pathway in human lung fibroblasts.

Schilter H, Cantemir-Stone CZ, Leksa V, Ohradanova-Repic A, Findlay AD, Deodhar M, Stockinger H, Song X, Molloy M, Marsh CB, Jarolimek W. Schilter H, et al. Immunol Lett. 2015 Jun;165(2):90-101. doi: 10.1016/j.imlet.2015.04.003. Epub 2015 Apr 27. Immunol Lett. 2015. PMID: 25929803 Free article.

8

Semicarbazide-sensitive amine oxidase inhibition ameliorates albuminuria and glomerulosclerosis but does not improve tubulointerstitial fibrosis in diabetic nephropathy.

Wong MY, Saad S, Wong MG, Stangenberg S, Jarolimek W, Schilter H, Zaky A, Gill A, Pollock C. Wong MY, et al. Among authors: schilter h. PLoS One. 2020 Jun 18;15(6):e0234617. doi: 10.1371/journal.pone.0234617. eCollection 2020. PLoS One. 2020. PMID: 32555665 Free PMC article.

9

The inhibitor of semicarbazide-sensitive amine oxidase, PXS-4728A, ameliorates key features of chronic obstructive pulmonary disease in a mouse model.

Jarnicki AG, Schilter H, Liu G, Wheeldon K, Essilfie AT, Foot JS, Yow TT, Jarolimek W, Hansbro PM. Jarnicki AG, et al. Among authors: schilter h. Br J Pharmacol. 2016 Nov;173(22):3161-3175. doi: 10.1111/bph.13573. Epub 2016 Oct 12. Br J Pharmacol. 2016. PMID: 27495192 Free PMC article.

10

Lysyl oxidase-like 2 inhibition ameliorates glomerulosclerosis and albuminuria in diabetic nephropathy.

Stangenberg S, Saad S, Schilter HC, Zaky A, Gill A, Pollock CA, Wong MG. Stangenberg S, et al. Among authors: schilter hc. Sci Rep. 2018 Jun 21;8(1):9423. doi: 10.1038/s41598-018-27462-6. Sci Rep. 2018. PMID: 29930330 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

17 results

Search Page

Filters