Castilho A - Search Results

1

Reteplase Fc-fusions produced in N. benthamiana are able to dissolve blood clots ex vivo.

Izadi S, Jalali Javaran M, Rashidi Monfared S, Castilho A. Izadi S, et al. Among authors: castilho a. PLoS One. 2021 Nov 30;16(11):e0260796. doi: 10.1371/journal.pone.0260796. eCollection 2021. PLoS One. 2021. PMID: 34847186 Free PMC article.

2

Significant impact of single N-glycan residues on the biological activity of Fc-based antibody-like fragments.

Jez J, Antes B, Castilho A, Kainer M, Wiederkum S, Grass J, Rüker F, Woisetschläger M, Steinkellner H. Jez J, et al. Among authors: castilho a. J Biol Chem. 2012 Jul 13;287(29):24313-9. doi: 10.1074/jbc.M112.360701. Epub 2012 May 15. J Biol Chem. 2012. PMID: 22589538 Free PMC article.

3

Generation of biologically active multi-sialylated recombinant human EPOFc in plants.

Castilho A, Neumann L, Gattinger P, Strasser R, Vorauer-Uhl K, Sterovsky T, Altmann F, Steinkellner H. Castilho A, et al. PLoS One. 2013;8(1):e54836. doi: 10.1371/journal.pone.0054836. Epub 2013 Jan 25. PLoS One. 2013. PMID: 23372778 Free PMC article.

4

Transient Expression of Mammalian Genes in N. benthamiana to Modulate N-Glycosylation.

Castilho A, Steinkellner H. Castilho A, et al. Methods Mol Biol. 2016;1385:99-113. doi: 10.1007/978-1-4939-3289-4_7. Methods Mol Biol. 2016. PMID: 26614284

5

Engineering the interactions between a plant-produced HIV antibody and human Fc receptors.

Stelter S, Paul MJ, Teh AY, Grandits M, Altmann F, Vanier J, Bardor M, Castilho A, Allen RL, Ma JK. Stelter S, et al. Among authors: castilho a. Plant Biotechnol J. 2020 Feb;18(2):402-414. doi: 10.1111/pbi.13207. Epub 2019 Aug 10. Plant Biotechnol J. 2020. PMID: 31301102 Free PMC article.

6

BGAL1 depletion boosts the level of β-galactosylation of N- and O-glycans in N. benthamiana.

Kriechbaum R, Ziaee E, Grünwald-Gruber C, Buscaill P, van der Hoorn RAL, Castilho A. Kriechbaum R, et al. Among authors: castilho a. Plant Biotechnol J. 2020 Jul;18(7):1537-1549. doi: 10.1111/pbi.13316. Epub 2020 Jan 11. Plant Biotechnol J. 2020. PMID: 31837192 Free PMC article.

7

Generation of enzymatically competent SARS-CoV-2 decoy receptor ACE2-Fc in glycoengineered Nicotiana benthamiana.

Castilho A, Schwestka J, Kienzl NF, Vavra U, Grünwald-Gruber C, Izadi S, Hiremath C, Niederhöfer J, Laurent E, Monteil V, Mirazimi A, Wirnsberger G, Stadlmann J, Stöger E, Mach L, Strasser R. Castilho A, et al. Biotechnol J. 2021 Jun;16(6):e2000566. doi: 10.1002/biot.202000566. Epub 2021 Feb 12. Biotechnol J. 2021. PMID: 33481336 Free PMC article.

8

The Instability of Dimeric Fc-Fusions Expressed in Plants Can Be Solved by Monomeric Fc Technology.

Gattinger P, Izadi S, Grünwald-Gruber C, Kallolimath S, Castilho A. Gattinger P, et al. Among authors: castilho a. Front Plant Sci. 2021 Jul 9;12:671728. doi: 10.3389/fpls.2021.671728. eCollection 2021. Front Plant Sci. 2021. PMID: 34305971 Free PMC article.

9

Assessment of transient expression strategies to sialylate recombinant proteins in N. benthamiana.

Izadi S, Kunnummel V, Steinkellner H, Werner S, Castilho A. Izadi S, et al. Among authors: castilho a. J Biotechnol. 2023 Mar 10;365:48-53. doi: 10.1016/j.jbiotec.2023.02.004. Epub 2023 Feb 15. J Biotechnol. 2023. PMID: 36805356 Free article. Review.

10

In planta deglycosylation improves the SARS-CoV-2 neutralization activity of recombinant ACE2-Fc.

Izadi S, Vavra U, Melnik S, Grünwald-Gruber C, Föderl-Höbenreich E, Sack M, Zatloukal K, Glössl J, Stöger E, Mach L, Castilho A, Strasser R. Izadi S, et al. Among authors: castilho a. Front Bioeng Biotechnol. 2023 May 3;11:1180044. doi: 10.3389/fbioe.2023.1180044. eCollection 2023. Front Bioeng Biotechnol. 2023. PMID: 37207124 Free PMC article.

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