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387 results

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Page 1
A new SPRING in lipid metabolism.
Hendrix S, Zelcer N. Hendrix S, et al. Curr Opin Lipidol. 2023 Oct 1;34(5):201-207. doi: 10.1097/MOL.0000000000000894. Epub 2023 Aug 3. Curr Opin Lipidol. 2023. PMID: 37548386 Review.
Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism.
Loregger A, Raaben M, Nieuwenhuis J, Tan JME, Jae LT, van den Hengel LG, Hendrix S, van den Berg M, Scheij S, Song JY, Huijbers IJ, Kroese LJ, Ottenhoff R, van Weeghel M, van de Sluis B, Brummelkamp T, Zelcer N. Loregger A, et al. Among authors: hendrix s. Nat Commun. 2020 Feb 28;11(1):1128. doi: 10.1038/s41467-020-14811-1. Nat Commun. 2020. PMID: 32111832 Free PMC article.
SPRING is a Dedicated Licensing Factor for SREBP-Specific Activation by S1P.
Hendrix S, Tan JME, Ndoj K, Kingma J, Valiloo M, Zijlstra LF, Ottenhoff R, Seidah NG, Loregger A, Kober DL, Zelcer N. Hendrix S, et al. Mol Cell Biol. 2024;44(4):123-137. doi: 10.1080/10985549.2024.2348711. Epub 2024 May 15. Mol Cell Biol. 2024. PMID: 38747374 Free article.
Glutamine sensing licenses cholesterol synthesis.
Garcia BM, Melchinger P, Medeiros T, Hendrix S, Prabhu K, Corrado M, Kingma J, Gorbatenko A, Deshwal S, Veronese M, Scorrano L, Pearce E, Giavalisco P, Zelcer N, Pernas L. Garcia BM, et al. Among authors: hendrix s. EMBO J. 2024 Dec;43(23):5837-5856. doi: 10.1038/s44318-024-00269-0. Epub 2024 Oct 21. EMBO J. 2024. PMID: 39433901 Free PMC article.
Key considerations for combination therapy in Alzheimer's clinical trials: Perspectives from an expert advisory board convened by the Alzheimer's drug discovery foundation.
Cummings J, Gold M, Mintun M, Irizarry M, von Eschenbach A, Hendrix S, Berry D, Sampaio C, Sink K, Landen J, Kivipelto M, Grundman M, Arnold SE, Green A, Partrick K, Nisenbaum L, Burstein A, Fillit H. Cummings J, et al. Among authors: hendrix s. J Prev Alzheimers Dis. 2025 Jan;12(1):100001. doi: 10.1016/j.tjpad.2024.100001. Epub 2025 Jan 1. J Prev Alzheimers Dis. 2025. PMID: 39800453 Free article.
Results of the ACTION-Galactosemia Kids Study to Evaluate the Effects of Govorestat in Pediatric Patients with Classic Galactosemia.
Bailey E, Phan H, Ahmad A, Thomas J, Ames EG, Pritchard AB, Quinonez SC, Wang S, Dayley C, Salt A, Pick C, Durrant A, Johnson S, Nicodemus-Johnson J, Dickson SP, Perfetti R, Hendrix SB, Shendelman S. Bailey E, et al. Among authors: hendrix sb. J Clin Pharmacol. 2024 Nov 21. doi: 10.1002/jcph.6170. Online ahead of print. J Clin Pharmacol. 2024. PMID: 39569553
387 results