Sisodia SS - Search Results

1

Gut microbiota-driven brain Aβ amyloidosis in mice requires microglia.

Dodiya HB, Lutz HL, Weigle IQ, Patel P, Michalkiewicz J, Roman-Santiago CJ, Zhang CM, Liang Y, Srinath A, Zhang X, Xia J, Olszewski M, Zhang X, Schipma MJ, Chang EB, Tanzi RE, Gilbert JA, Sisodia SS. Dodiya HB, et al. Among authors: sisodia ss. J Exp Med. 2022 Jan 3;219(1):e20200895. doi: 10.1084/jem.20200895. Epub 2021 Dec 2. J Exp Med. 2022. PMID: 34854884 Free PMC article.

2

Alzheimer's disease: genetic studies and transgenic models.

Price DL, Tanzi RE, Borchelt DR, Sisodia SS. Price DL, et al. Among authors: sisodia ss. Annu Rev Genet. 1998;32:461-93. doi: 10.1146/annurev.genet.32.1.461. Annu Rev Genet. 1998. PMID: 9928488 Review.

3

Presenilin 1 mutants impair the self-renewal and differentiation of adult murine subventricular zone-neuronal progenitors via cell-autonomous mechanisms involving notch signaling.

Veeraraghavalu K, Choi SH, Zhang X, Sisodia SS. Veeraraghavalu K, et al. Among authors: sisodia ss. J Neurosci. 2010 May 19;30(20):6903-15. doi: 10.1523/JNEUROSCI.0527-10.2010. J Neurosci. 2010. PMID: 20484632 Free PMC article.

4

Modulation of gamma-secretase reduces beta-amyloid deposition in a transgenic mouse model of Alzheimer's disease.

Kounnas MZ, Danks AM, Cheng S, Tyree C, Ackerman E, Zhang X, Ahn K, Nguyen P, Comer D, Mao L, Yu C, Pleynet D, Digregorio PJ, Velicelebi G, Stauderman KA, Comer WT, Mobley WC, Li YM, Sisodia SS, Tanzi RE, Wagner SL. Kounnas MZ, et al. Among authors: sisodia ss. Neuron. 2010 Sep 9;67(5):769-80. doi: 10.1016/j.neuron.2010.08.018. Neuron. 2010. PMID: 20826309 Free PMC article.

5

Identification of NEEP21 as a ß-amyloid precursor protein-interacting protein in vivo that modulates amyloidogenic processing in vitro.

Norstrom EM, Zhang C, Tanzi R, Sisodia SS. Norstrom EM, et al. Among authors: sisodia ss. J Neurosci. 2010 Nov 17;30(46):15677-85. doi: 10.1523/JNEUROSCI.4464-10.2010. J Neurosci. 2010. PMID: 21084623 Free PMC article.

6

A role for presenilins in autophagy revisited: normal acidification of lysosomes in cells lacking PSEN1 and PSEN2.

Zhang X, Garbett K, Veeraraghavalu K, Wilburn B, Gilmore R, Mirnics K, Sisodia SS. Zhang X, et al. Among authors: sisodia ss. J Neurosci. 2012 Jun 20;32(25):8633-48. doi: 10.1523/JNEUROSCI.0556-12.2012. J Neurosci. 2012. PMID: 22723704 Free PMC article.

7

Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models".

Veeraraghavalu K, Zhang C, Miller S, Hefendehl JK, Rajapaksha TW, Ulrich J, Jucker M, Holtzman DM, Tanzi RE, Vassar R, Sisodia SS. Veeraraghavalu K, et al. Among authors: sisodia ss. Science. 2013 May 24;340(6135):924-f. doi: 10.1126/science.1235505. Science. 2013. PMID: 23704555

8

Endogenous expression of FAD-linked PS1 impairs proliferation, neuronal differentiation and survival of adult hippocampal progenitors.

Veeraraghavalu K, Choi SH, Zhang X, Sisodia SS. Veeraraghavalu K, et al. Among authors: sisodia ss. Mol Neurodegener. 2013 Oct 20;8:41. doi: 10.1186/1750-1326-8-41. Mol Neurodegener. 2013. PMID: 24138759 Free PMC article.

9

Soluble γ-secretase modulators selectively inhibit the production of the 42-amino acid amyloid β peptide variant and augment the production of multiple carboxy-truncated amyloid β species.

Wagner SL, Zhang C, Cheng S, Nguyen P, Zhang X, Rynearson KD, Wang R, Li Y, Sisodia SS, Mobley WC, Tanzi RE. Wagner SL, et al. Among authors: sisodia ss. Biochemistry. 2014 Feb 4;53(4):702-13. doi: 10.1021/bi401537v. Epub 2014 Jan 22. Biochemistry. 2014. PMID: 24401146 Free PMC article.

10

Age-dependent, non-cell-autonomous deposition of amyloid from synthesis of β-amyloid by cells other than excitatory neurons.

Veeraraghavalu K, Zhang C, Zhang X, Tanzi RE, Sisodia SS. Veeraraghavalu K, et al. Among authors: sisodia ss. J Neurosci. 2014 Mar 5;34(10):3668-73. doi: 10.1523/JNEUROSCI.5079-13.2014. J Neurosci. 2014. PMID: 24599465 Free PMC article.

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