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People critically ill with COVID-19 exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 lung viral burden.
Cillo AR, Somasundaram A, Shan F, Cardello C, Workman CJ, Kitsios GD, Ruffin AT, Kunning S, Lampenfeld C, Onkar S, Grebinoski S, Deshmukh G, Methe B, Liu C, Nambulli S, Andrews LP, Duprex WP, Joglekar AV, Benos PV, Ray P, Ray A, McVerry BJ, Zhang Y, Lee JS, Das J, Singh H, Morris A, Bruno TC, Vignali DAA. Cillo AR, et al. Among authors: das j. Cell Rep Med. 2021 Dec 21;2(12):100476. doi: 10.1016/j.xcrm.2021.100476. Epub 2021 Dec 2. Cell Rep Med. 2021. PMID: 34873589 Free PMC article.
Bifurcated monocyte states are predictive of mortality in severe COVID-19.
Cillo AR, Somasundaram A, Shan F, Cardello C, Workman CJ, Kitsios GD, Ruffin A, Kunning S, Lampenfeld C, Onkar S, Grebinoski S, Deshmukh G, Methe B, Liu C, Nambulli S, Andrews L, Duprex WP, Joglekar AV, Benos PV, Ray P, Ray A, McVerry BJ, Zhang Y, Lee JS, Das J, Singh H, Morris A, Bruno TC, Vignali DAA. Cillo AR, et al. Among authors: das j. bioRxiv [Preprint]. 2021 Feb 10:2021.02.10.430499. doi: 10.1101/2021.02.10.430499. bioRxiv. 2021. PMID: 33594364 Free PMC article. Preprint.
Antibodies targeting conserved non-canonical antigens and endemic coronaviruses associate with favorable outcomes in severe COVID-19.
Peddireddy SP, Rahman SA, Cillo AR, Vijay GM, Somasundaram A, Workman CJ, Bain W, McVerry BJ, Methe B, Lee JS, Ray P, Ray A, Bruno TC, Vignali DAA, Kitsios GD, Morris A, Singh H, Sarkar A, Das J. Peddireddy SP, et al. Among authors: das j. Cell Rep. 2022 Jun 28;39(13):111020. doi: 10.1016/j.celrep.2022.111020. Epub 2022 Jun 13. Cell Rep. 2022. PMID: 35738278 Free PMC article.
Lipidomic signatures align with inflammatory patterns and outcomes in critical illness.
Wu J, Cyr A, Gruen DS, Lovelace TC, Benos PV, Das J, Kar UK, Chen T, Guyette FX, Yazer MH, Daley BJ, Miller RS, Harbrecht BG, Claridge JA, Phelan HA, Zuckerbraun BS, Neal MD, Johansson PI, Stensballe J, Namas RA, Vodovotz Y, Sperry JL, Billiar TR; PAMPer study group. Wu J, et al. Among authors: das j. Nat Commun. 2022 Nov 10;13(1):6789. doi: 10.1038/s41467-022-34420-4. Nat Commun. 2022. PMID: 36357394 Free PMC article.
Altered AP-1, RUNX and EGR chromatin dynamics drive fibrotic lung disease.
Valenzi E, Jia M, Gerges P, Fan J, Tabib T, Behara R, Zhou Y, Sembrat J, Das J, Benos PV, Singh H, Lafyatis R. Valenzi E, et al. Among authors: das j. bioRxiv [Preprint]. 2024 Oct 28:2024.10.23.619858. doi: 10.1101/2024.10.23.619858. bioRxiv. 2024. PMID: 39554071 Free PMC article. Preprint.
Co-immunization of DNA and Protein in the Same Anatomical Sites Induces Superior Protective Immune Responses against SHIV Challenge.
Felber BK, Lu Z, Hu X, Valentin A, Rosati M, Remmel CAL, Weiner JA, Carpenter MC, Faircloth K, Stanfield-Oakley S, Williams WB, Shen X, Tomaras GD, LaBranche CC, Montefiori D, Trinh HV, Rao M, Alam MS, Vandergrift NA, Saunders KO, Wang Y, Rountree W, Das J, Alter G, Reed SG, Aye PP, Schiro F, Pahar B, Dufour JP, Veazey RS, Marx PA, Venzon DJ, Shaw GM, Ferrari G, Ackerman ME, Haynes BF, Pavlakis GN. Felber BK, et al. Among authors: das j. Cell Rep. 2020 May 12;31(6):107624. doi: 10.1016/j.celrep.2020.107624. Cell Rep. 2020. PMID: 32402293 Free PMC article.
1,954 results