Potter BVL - Search Results

1

Small Molecule CD38 Inhibitors: Synthesis of 8-Amino-N1-inosine 5'-monophosphate, Analogues and Early Structure-Activity Relationship.

Watt JM, Graeff R, Potter BVL. Watt JM, et al. Among authors: potter bvl. Molecules. 2021 Nov 26;26(23):7165. doi: 10.3390/molecules26237165. Molecules. 2021. PMID: 34885748 Free PMC article.

2

First enzymatic synthesis of an N1-cyclised cADPR (cyclic-ADP ribose) analogue with a hypoxanthine partial structure: discovery of a membrane permeant cADPR agonist.

Wagner GK, Black S, Guse AH, Potter BV. Wagner GK, et al. Chem Commun (Camb). 2003 Aug 7;(15):1944-5. doi: 10.1039/b305660k. Chem Commun (Camb). 2003. PMID: 12932045

3

Aplysia californica mediated cyclisation of novel 3'-modified NAD+ analogues: a role for hydrogen bonding in the recognition of cyclic adenosine 5'-diphosphate ribose.

Mort CJ, Migaud ME, Galione A, Potter BV. Mort CJ, et al. Bioorg Med Chem. 2004 Jan 15;12(2):475-87. doi: 10.1016/j.bmc.2003.10.012. Bioorg Med Chem. 2004. PMID: 14723966

4

Unusual entry to the novel 8-halo-N1-ribosyl hypoxanthine system by degradation of a cyclic adenosine-5'-diphosphate ribose analogue.

Moreau C, Woodman TJ, Potter BV. Moreau C, et al. Chem Commun (Camb). 2006 Mar 14;(10):1127-9. doi: 10.1039/b517916e. Epub 2006 Jan 25. Chem Commun (Camb). 2006. PMID: 16514461

5

Structural determinants for N1/N7 cyclization of nicotinamide hypoxanthine 5'-dinucleotide (NHD+) derivatives by ADP-ribosyl cyclase from aplysia californica: Ca2+-mobilizing activity of 8-substituted cyclic inosine 5'-diphosphoribose analogues in T-lymphocytes.

Moreau C, Wagner GK, Weber K, Guse AH, Potter BV. Moreau C, et al. J Med Chem. 2006 Aug 24;49(17):5162-76. doi: 10.1021/jm060275a. J Med Chem. 2006. PMID: 16913705

6

Catalysis-associated conformational changes revealed by human CD38 complexed with a non-hydrolyzable substrate analog.

Liu Q, Kriksunov IA, Moreau C, Graeff R, Potter BV, Lee HC, Hao Q. Liu Q, et al. J Biol Chem. 2007 Aug 24;282(34):24825-32. doi: 10.1074/jbc.M701653200. Epub 2007 Jun 25. J Biol Chem. 2007. PMID: 17591784 Free article.

7

Chemoenzymatic synthesis of 7-deaza cyclic adenosine 5'-diphosphate ribose analogues, membrane-permeant modulators of intracellular calcium release.

Zhang B, Bailey VC, Potter BV. Zhang B, et al. J Org Chem. 2008 Mar 7;73(5):1693-703. doi: 10.1021/jo071236p. Epub 2008 Jan 30. J Org Chem. 2008. PMID: 18229937

8

2'-deoxy cyclic adenosine 5'-diphosphate ribose derivatives: importance of the 2'-hydroxyl motif for the antagonistic activity of 8-substituted cADPR derivatives.

Zhang B, Wagner GK, Weber K, Garnham C, Morgan AJ, Galione A, Guse AH, Potter BV. Zhang B, et al. J Med Chem. 2008 Mar 27;51(6):1623-36. doi: 10.1021/jm7010386. Epub 2008 Feb 28. J Med Chem. 2008. PMID: 18303825

9

Structural basis for enzymatic evolution from a dedicated ADP-ribosyl cyclase to a multifunctional NAD hydrolase.

Liu Q, Graeff R, Kriksunov IA, Jiang H, Zhang B, Oppenheimer N, Lin H, Potter BV, Lee HC, Hao Q. Liu Q, et al. J Biol Chem. 2009 Oct 2;284(40):27637-45. doi: 10.1074/jbc.M109.031005. Epub 2009 Jul 28. J Biol Chem. 2009. PMID: 19640846 Free PMC article.

10

Synthesis of cyclic adenosine 5'-diphosphate ribose analogues: a C2'endo/syn "southern" ribose conformation underlies activity at the sea urchin cADPR receptor.

Moreau C, Ashamu GA, Bailey VC, Galione A, Guse AH, Potter BV. Moreau C, et al. Org Biomol Chem. 2011 Jan 7;9(1):278-90. doi: 10.1039/c0ob00396d. Epub 2010 Oct 25. Org Biomol Chem. 2011. PMID: 20976353 Free PMC article.

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