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Using multivariable Mendelian randomization to estimate the causal effect of bone mineral density on osteoarthritis risk, independently of body mass index.
Hartley A, Sanderson E, Granell R, Paternoster L, Zheng J, Smith GD, Southam L, Hatzikotoulas K, Boer CG, van Meurs J, Zeggini E; Genetics of Osteoarthritis Consortium; Gregson CL, Tobias JH. Hartley A, et al. Among authors: boer cg. Int J Epidemiol. 2022 Aug 10;51(4):1254-1267. doi: 10.1093/ije/dyab251. Int J Epidemiol. 2022. PMID: 34897459 Free PMC article.
Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis.
Castaño-Betancourt MC, Evans DS, Ramos YF, Boer CG, Metrustry S, Liu Y, den Hollander W, van Rooij J, Kraus VB, Yau MS, Mitchell BD, Muir K, Hofman A, Doherty M, Doherty S, Zhang W, Kraaij R, Rivadeneira F, Barrett-Connor E, Maciewicz RA, Arden N, Nelissen RG, Kloppenburg M, Jordan JM, Nevitt MC, Slagboom EP, Hart DJ, Lafeber F, Styrkarsdottir U, Zeggini E, Evangelou E, Spector TD, Uitterlinden AG, Lane NE, Meulenbelt I, Valdes AM, van Meurs JB. Castaño-Betancourt MC, et al. Among authors: boer cg. PLoS Genet. 2016 Oct 4;12(10):e1006260. doi: 10.1371/journal.pgen.1006260. eCollection 2016 Oct. PLoS Genet. 2016. PMID: 27701424 Free PMC article.
Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus.
Medina-Gomez C, Kemp JP, Dimou NL, Kreiner E, Chesi A, Zemel BS, Bønnelykke K, Boer CG, Ahluwalia TS, Bisgaard H, Evangelou E, Heppe DHM, Bonewald LF, Gorski JP, Ghanbari M, Demissie S, Duque G, Maurano MT, Kiel DP, Hsu YH, C J van der Eerden B, Ackert-Bicknell C, Reppe S, Gautvik KM, Raastad T, Karasik D, van de Peppel J, Jaddoe VWV, Uitterlinden AG, Tobias JH, Grant SFA, Bagos PG, Evans DM, Rivadeneira F. Medina-Gomez C, et al. Among authors: boer cg. Nat Commun. 2017 Jul 25;8(1):121. doi: 10.1038/s41467-017-00108-3. Nat Commun. 2017. PMID: 28743860 Free PMC article.
Genome-wide association and functional studies identify a role for matrix Gla protein in osteoarthritis of the hand.
den Hollander W, Boer CG, Hart DJ, Yau MS, Ramos YFM, Metrustry S, Broer L, Deelen J, Cupples LA, Rivadeneira F, Kloppenburg M, Peters M, Spector TD, Hofman A, Slagboom PE, Nelissen RGHH, Uitterlinden AG, Felson DT, Valdes AM, Meulenbelt I, van Meurs JJB. den Hollander W, et al. Among authors: boer cg. Ann Rheum Dis. 2017 Dec;76(12):2046-2053. doi: 10.1136/annrheumdis-2017-211214. Epub 2017 Aug 30. Ann Rheum Dis. 2017. PMID: 28855172 Free PMC article.
Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects.
Medina-Gomez C, Kemp JP, Trajanoska K, Luan J, Chesi A, Ahluwalia TS, Mook-Kanamori DO, Ham A, Hartwig FP, Evans DS, Joro R, Nedeljkovic I, Zheng HF, Zhu K, Atalay M, Liu CT, Nethander M, Broer L, Porleifsson G, Mullin BH, Handelman SK, Nalls MA, Jessen LE, Heppe DHM, Richards JB, Wang C, Chawes B, Schraut KE, Amin N, Wareham N, Karasik D, Van der Velde N, Ikram MA, Zemel BS, Zhou Y, Carlsson CJ, Liu Y, McGuigan FE, Boer CG, Bønnelykke K, Ralston SH, Robbins JA, Walsh JP, Zillikens MC, Langenberg C, Li-Gao R, Williams FMK, Harris TB, Akesson K, Jackson RD, Sigurdsson G, den Heijer M, van der Eerden BCJ, van de Peppel J, Spector TD, Pennell C, Horta BL, Felix JF, Zhao JH, Wilson SG, de Mutsert R, Bisgaard H, Styrkársdóttir U, Jaddoe VW, Orwoll E, Lakka TA, Scott R, Grant SFA, Lorentzon M, van Duijn CM, Wilson JF, Stefansson K, Psaty BM, Kiel DP, Ohlsson C, Ntzani E, van Wijnen AJ, Forgetta V, Ghanbari M, Logan JG, Williams GR, Bassett JHD, Croucher PI, Evangelou E, Uitterlinden AG, Ackert-Bicknell CL, Tobias JH, Evans DM, Rivadeneira F. Medina-Gomez C, et al. Among authors: boer cg. Am J Hum Genet. 2018 Jan 4;102(1):88-102. doi: 10.1016/j.ajhg.2017.12.005. Am J Hum Genet. 2018. PMID: 29304378 Free PMC article.
Development of a prediction model for future risk of radiographic hip osteoarthritis.
Saberi Hosnijeh F, Kavousi M, Boer CG, Uitterlinden AG, Hofman A, Reijman M, Oei EHG, Bierma-Zeinstra SM, van Meurs JBJ. Saberi Hosnijeh F, et al. Among authors: boer cg. Osteoarthritis Cartilage. 2018 Apr;26(4):540-546. doi: 10.1016/j.joca.2018.01.015. Epub 2018 Jan 31. Osteoarthritis Cartilage. 2018. PMID: 29382605 Free article.
A systematic analysis highlights multiple long non-coding RNAs associated with cardiometabolic disorders.
Ghanbari M, Peters MJ, de Vries PS, Boer CG, van Rooij JGJ, Lee YC, Kumar V, Uitterlinden AG, Ikram MA, Wijmenga C, Ordovas JM, Smith CE, van Meurs JBJ, Erkeland SJ, Franco OH, Dehghan A. Ghanbari M, et al. Among authors: boer cg. J Hum Genet. 2018 Apr;63(4):431-446. doi: 10.1038/s10038-017-0403-x. Epub 2018 Jan 30. J Hum Genet. 2018. PMID: 29382920 Free PMC article.
Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis.
Zengini E, Hatzikotoulas K, Tachmazidou I, Steinberg J, Hartwig FP, Southam L, Hackinger S, Boer CG, Styrkarsdottir U, Gilly A, Suveges D, Killian B, Ingvarsson T, Jonsson H, Babis GC, McCaskie A, Uitterlinden AG, van Meurs JBJ, Thorsteinsdottir U, Stefansson K, Davey Smith G, Wilkinson JM, Zeggini E. Zengini E, et al. Among authors: boer cg. Nat Genet. 2018 Apr;50(4):549-558. doi: 10.1038/s41588-018-0079-y. Epub 2018 Mar 20. Nat Genet. 2018. PMID: 29559693 Free PMC article.
Genome-wide association study identifies nine novel loci for 2D:4D finger ratio, a putative retrospective biomarker of testosterone exposure in utero.
Warrington NM, Shevroja E, Hemani G, Hysi PG, Jiang Y, Auton A, Boer CG, Mangino M, Wang CA, Kemp JP, McMahon G, Medina-Gomez C, Hickey M, Trajanoska K, Wolke D, Ikram MA; 23andMe Research Team; Montgomery GW, Felix JF, Wright MJ, Mackey DA, Jaddoe VW, Martin NG, Tung JY, Davey Smith G, Pennell CE, Spector TD, van Meurs J, Rivadeneira F, Medland SE, Evans DM. Warrington NM, et al. Among authors: boer cg. Hum Mol Genet. 2018 Jun 1;27(11):2025-2038. doi: 10.1093/hmg/ddy121. Hum Mol Genet. 2018. PMID: 29659830 Free PMC article.
Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain.
Suri P, Palmer MR, Tsepilov YA, Freidin MB, Boer CG, Yau MS, Evans DS, Gelemanovic A, Bartz TM, Nethander M, Arbeeva L, Karssen L, Neogi T, Campbell A, Mellstrom D, Ohlsson C, Marshall LM, Orwoll E, Uitterlinden A, Rotter JI, Lauc G, Psaty BM, Karlsson MK, Lane NE, Jarvik GP, Polasek O, Hochberg M, Jordan JM, Van Meurs JBJ, Jackson R, Nielson CM, Mitchell BD, Smith BH, Hayward C, Smith NL, Aulchenko YS, Williams FMK. Suri P, et al. Among authors: boer cg. PLoS Genet. 2018 Sep 27;14(9):e1007601. doi: 10.1371/journal.pgen.1007601. eCollection 2018 Sep. PLoS Genet. 2018. PMID: 30261039 Free PMC article.
83 results